Duotrol Tablet

Composition of Duotrol Tablet

Duotrol Tablet contains Glibenclamide (5mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.

Uses of Duotrol Tablet

• reduces diarrhea symptoms
• restores bowel movements
• effective relief

Key benefits

• In Type 2 diabetes mellitus Type 2 diabetes mellitus is a long-term condition where the body cannot effectively regulate blood sugar levels. Duotrol Tablet is used to control high blood sugar by increasing insulin release and reducing glucose production in the liver. This helps maintain stable blood sugar levels
• lowers the risk of complications
• and supports better day-to-day energy and health in people with diabetes.

How Duotrol Tablet works

Sulfonylurea that stimulates pancreatic insulin release and improves sensitivity.; Decreases hepatic glucose production and improves insulin sensitivity; acts in liver and gut.

How to take Duotrol Tablet

Take 1 tablet after each loose stool, up to 4 tablets daily

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Duotrol Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Duotrol Tablet

Most side effects of Duotrol are mild and settle as the body adjusts. Reported side effects include:

• Low blood sugar
• weight gain.; GI upset (nausea
• diarrhea); rare risk of lactic acidosis.

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Duotrol Tablet

Warnings and precautions

Carry sugar source for hypoglycemia; review during illness or fasting.; Inform clinician about kidney problems; withhold around iodinated contrast when advised.

Do not take Duotrol if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Duotrol Tablet

Store below 25°C; protect from moisture.

Expert advice for Duotrol Tablet

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Duotrol Tablet. Take it with food to lower your chance of having an upset stomach. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Duotrol Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice). Take it with food to lower your chance of having an upset stomach. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Duotrol Tablet. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Duotrol Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

USV LIMITED

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea and Biguanide