Gemerdapa 5/2/500 Tablet

Composition of Gemerdapa 5/2/500 Tablet

Gemerdapa 5/2/500 Tablet contains Dapagliflozin 5 mg + Glimepiride 2 mg + Metformin 500 mg (as Metformin HCl) per tablet. It belongs to the SGLT2 inhibitor + Sulfonylurea + Biguanide class of medicines.

Uses of Gemerdapa 5/2/500 Tablet

Type 2 diabetes mellitus: to improve blood glucose control in adults when diet and exercise alone or current therapy is inadequate.

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin sensitivity
• Reduces glucose reabsorption leading to glucose loss in urine
• Helps achieve better HbA1c control with combination therapy
• May support modest weight reduction (dapagliflozin component)

How Gemerdapa 5/2/500 Tablet works

Metformin decreases hepatic glucose production and improves insulin sensitivity. Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells. Dapagliflozin (an SGLT2 inhibitor) increases urinary glucose excretion by reducing glucose reabsorption in the kidneys.

How to take Gemerdapa 5/2/500 Tablet

Oral tablet; take exactly as prescribed by the doctor, usually once daily with food (preferably with the first main meal) to reduce stomach upset. Swallow whole with water; do not crush/chew. Monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Gemerdapa 5/2/500 as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Gemerdapa 5/2/500 than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Gemerdapa 5/2/500 Tablet

Most side effects of Gemerdapa 5/2/500 are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• nausea
• vomiting
• diarrhoea
• abdominal discomfort
• headache
• dizziness
• increased urination
• thirst
• genital fungal infection
• urinary tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Gemerdapa 5/2/500 Tablet

Warnings and precautions

Risk of hypoglycaemia (higher with missed meals, alcohol, heavy exercise or with other antidiabetics); metformin-associated lactic acidosis (seek urgent care for rapid breathing, severe weakness, abdominal pain); stop metformin temporarily before/after iodinated contrast procedures and during severe illness/dehydration; dapagliflozin may cause dehydration/low BP, ketoacidosis (can occur with normal sugars), serious genital infections; monitor renal function—use not recommended in severe kidney impairment; caution in elderly and those on diuretics; not for type 1 diabetes.

Interactions with other medicines

Insulin/other sulfonylureas (increased hypoglycaemia), diuretics (increased dehydration/hypotension), ACE inhibitors/ARBs (may enhance glucose lowering), corticosteroids and sympathomimetics (raise glucose), rifampicin (may reduce glimepiride effect), azole antifungals/clarithromycin (may increase glimepiride effect), alcohol (increases hypoglycaemia and lactic acidosis risk), iodinated contrast media (lactic acidosis risk with metformin), carbonic anhydrase inhibitors like topiramate (may increase acidosis risk)

How to store Gemerdapa 5/2/500 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Manufacturer and class

Manufacturer:

SUN PHARMA

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + Sulfonylurea + Biguanide