Glimestar-Sm1 Forte Tablet

Composition of Glimestar-Sm1 Forte Tablet

Glimestar-Sm1 Forte Tablet contains Sitagliptin (50mg) + Glimepiride (1mg) + Metformin (1000mg). It belongs to the DPP-4 inhibitor, Sulfonylurea and Biguanide class of medicines.

Uses of Glimestar-Sm1 Forte Tablet

Treatment of Type 2 diabetes mellitus

Key benefits

• In Treatment of Type 2 diabetes mellitus Lowering blood glucose levels is an essential part of managing diabetes as this helps to reduce the risk of serious diabetes-associated complications
• such as kidney damage
• eye damage
• nerve problems
• and loss of limbs. Glimestar-SM1 Forte Tablet helps control high blood glucose (sugar) levels. It also reduces the risk of heart diseases like heart attack or stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal
• healthy life.

How Glimestar-Sm1 Forte Tablet works

Glimestar-SM1 Forte Tablet is a combination of three antidiabetic medications. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood. Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels).

How to take Glimestar-Sm1 Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glimestar-SM1 Forte Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Glimestar-SM1 Forte Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glimestar-Sm1 Forte Tablet

Most side effects of Glimestar-Sm1 Forte are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glimestar-Sm1 Forte Tablet

Warnings and precautions

Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Glimestar-Sm1 Forte if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Glimestar-Sm1 Forte Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Glimestar-Sm1 Forte Tablet

Prefer taking Glimestar-SM1 Forte Tablet after a meal or with a snack, as this will reduce the chance of an upset stomach. Glimestar-SM1 Forte Tablet may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety. If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting. Monitor your blood sugar regularly while taking this medicine. Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.

Manufacturer and class

Manufacturer:

MANKIND (PHARMA)

Therapeutic class:

ANTI DIABETIC

Drug class:

DPP-4 inhibitor, Sulfonylurea and Biguanide