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Prescription requiredPristine Pearl PharmaANTI DIABETIC

Glymiprl 1000 Tablet

Glimepiride (2mg) + Metformin (500mg)

Glymiprl 1000 Tablet is used for treatment of Type 2 diabetes mellitus Hormone replacement therapy.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

₹33₹3.28 per tablet
100% genuine medicinesPharmacist-verified orderDelivered across India

Key details

Salt: Glimepiride (2mg) + Metformin (500mg)
Available variants: tablet tablet 10`S
Best price: ₹33 (₹3.28 per tablet)
Prescription: Required
Manufacturer: PRISTINE PEARL PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Glymiprl 1000 Tablet

Glymiprl 1000 Tablet contains Glimepiride (2mg) + Metformin (500mg).

Uses of Glymiprl 1000 Tablet

Treatment of Type 2 diabetes mellitus Hormone replacement therapy

Key benefits

  • In Treatment of Type 2 diabetes mellitus Glymiprl M 2mg/500mg Tablet is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level
  • you will reduce the risk of getting any of the serious complications of diabetes
  • such as kidney damage
  • eye damage
  • nerve problems
  • and loss of limbs. Taking this medicine regularly
  • along with proper diet and exercise
  • will help you live a normal
  • healthy life. In Hormone replacement therapy In patients already controlled on separate treatment with glimepiride and metformin
  • this combination may be used as a replacement to simplify treatment while maintaining blood sugar control. It is indicated in adults 18 years and older. Show More

How Glymiprl 1000 Tablet works

Glymiprl M 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

How to take Glymiprl 1000 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glymiprl M 2mg/500mg Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Glymiprl M 2mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

Taking more Glymiprl than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Glymiprl 1000 Tablet

Most side effects of Glymiprl are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glymiprl 1000 Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving CAUTION
KidneyKidney UNSAFE
LiverLiver UNSAFE
Habit formingNo

Interactions with other medicines

Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Glymiprl. Some combinations can change how Glymiprl works or raise the chance of side effects.

How to store Glymiprl 1000 Tablet

Store Glymiprl below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.

Expert advice for Glymiprl 1000 Tablet

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glymiprl M 2mg/500mg Tablet. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glymiprl M 2mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:
PRISTINE PEARL PHARMA
Therapeutic class:
ANTI DIABETIC

Substitutes for Glymiprl 1000 Tablet

Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Glymiprl 1000 Tablet
Ozomet G2 TabletOZONE PHARMACEUTICALS LTDtablet · 15`S₹5567% more
Glucobeat G2 TabletSAAN LAB LLPtablet · 10`S₹6185% more
Glytime M 1 mg TabletXYRIS LIFE SCIENCES PVT LTDtablet · 10`S₹6186% more
Glimedose M1 TabletMSV LIFESCIENCEStablet · 10`S₹6598% more
Biopride M2 TabletLIVIDUS PHARMACEUTICALS PVT LTD.`tablet · 10`S₹70114% more
Gilmet 2FIZIKS LIFE SCIENCE10`S₹79140% more
Glytime M 2 mg TabletXYRIS LIFE SCIENCES PVT LTDtablet · 10`S₹80143% more
Glycomet Gp 1 ForteUSV Ltd10`S₹96192% more
Glynamic M2 TabletFUSION HEALTH CAREtablet · 10`S₹113244% more
Yogamet gm 2 TabletHIGLANCEtablet · 10`S₹118259% more
Humiglim 1 mg TabletVERSE LIFESCIENCEStablet · 30`S₹120266% more
Diapride M 1MICRO LABS15`S₹152363% more
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Glymiprl 1000 Tablet FAQs

What is Glymiprl 1000 Tablet used for?
Glymiprl 1000 Tablet is commonly used for Treatment of Type 2 diabetes mellitus Hormone replacement therapy. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Glymiprl 1000 Tablet?
Glymiprl 1000 Tablet contains Glimepiride (2mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Glymiprl 1000 Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Glymiprl 1000 Tablet work?
Glymiprl M 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin.
Is Glymiprl 1000 Tablet a prescription medicine?
Yes. Glymiprl 1000 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Glymiprl 1000 Tablet?
The side effects reported most often with Glymiprl are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Glymiprl 1000 Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Glymiprl.
Can I drink alcohol while taking Glymiprl 1000 Tablet?
Alcohol UNSAFE
What if I miss a dose of Glymiprl 1000 Tablet?
If you miss a dose of Glymiprl M 2mg/500mg Tablet, take it as soon as possible.
Is Glymiprl 1000 Tablet habit forming?
No. Glymiprl 1000 Tablet is not known to be habit forming when taken as prescribed.
How much does Glymiprl 1000 Tablet cost on PingMeDoc Pharmacy?
Glymiprl 1000 Tablet starts at ₹33 on PingMeDoc Pharmacy. Available in tablet tablet 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Glymiprl 1000 Tablet?
Glymiprl 1000 Tablet is manufactured by PRISTINE PEARL PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Glymiprl 1000 Tablet delivered?
Glymiprl 1000 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Glymiprl 1000 Tablet, Quick facts

Salt
Glimepiride (2mg) + Metformin (500mg)
Form
tablet
Best price
₹33 (₹3.28 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
PRISTINE PEARL PHARMA
Manufacturer
PRISTINE PEARL PHARMA
Therapeutic class
ANTI DIABETIC
Habit forming
No
Variants
tablet tablet 10`S
Delivery
Standard across India

References

The information on Glymiprl 1000 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  2. National List of Essential Medicines (NLEM) 2022, Government of India.
  3. Manufacturer's package insert / prescribing information for Glymiprl 1000 Tablet.
  4. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

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Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.