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Prescription requiredKarnataka Antibiotics & PharmaAnti-hypertensive and Diuretic

Lotace 50-H

Losartan (50mg) + Hydrochlorothiazide (12.5mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Losartar H₹85View
  • Zaart-H Tablet₹90View
  • Cosart H Tablet₹92View

Lotace 50-H is used for lotace H Tablet is used in the treatment of high blood pressure.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Losartan (50mg) + Hydrochlorothiazide (12.5mg)
Available variants: NA 10`S
Best price: ₹64
MRP: ₹68
Prescription: Required
Manufacturer: KARNATAKA ANTIBIOTICS & PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Lotace 50-H

Lotace 50-H contains Losartan (50mg) + Hydrochlorothiazide (12.5mg). It belongs to the Angiotensin receptor blocker / ACE inhibitor and Water tablet class of medicines.

Uses of Lotace 50-H

Lotace H Tablet is used in the treatment of high blood pressure.

Key benefits

  • Protects the kidneys in diabetes
  • Reduces the long-term risk of stroke and heart attack
  • Usually taken once a day
  • Relieves swelling and breathlessness caused by fluid
  • Long-established blood pressure treatment
  • Inexpensive and once daily

How Lotace 50-H works

Lotace H Tablet is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

How to take Lotace 50-H

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lotace H Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. It can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lotace 50-H

Most side effects of Lotace 50-H are mild and settle as the body adjusts. Reported side effects include:

  • Nausea Taste change Stomach upset Diarrhea Headache Dizziness Weakness Decreased blood pressure Increased blood uric acid Increased blood lipid level Glucose intolerance Electrolyte imbalance

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lotace 50-H

PregnancyLotace H Tablet is unsafe to use during pregnancy.<br>There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
BreastfeedingLotace H Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholTaking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyLotace H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Lotace H Tablet may be needed. Please consult your doctor.<br>Use of Lotace H Tablet is not recommended in patients with severe kidney disease.
LiverLotace H Tablet should be used with caution in patients with liver disease. Dose adjustment of Lotace H Tablet may be needed. Please consult your doctor.
Habit formingNo

Warnings and precautions

Stand up slowly for the first few days — dizziness on rising is common when you start or your dose goes up. Stop and seek urgent care if your lips, tongue, face or throat swell, or you have difficulty breathing. A persistent dry, tickly cough can be caused by the ACE inhibitor group; tell your doctor rather than stopping on your own, as an alternative exists. Your doctor will check your kidney function and potassium after starting and after any dose change. Do not use salt substitutes containing potassium without asking your doctor. Take it in the morning so that passing urine does not disturb your sleep. Your doctor will check your salts and kidney function with blood tests — do not skip them. Report muscle cramps, marked weakness, confusion or an irregular heartbeat; these can be signs your potassium or sodium has fallen. In hot weather or during an illness with vomiting or loose motions, tell your doctor — you may become dehydrated quickly.

Do not take Lotace 50-H if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Anti-inflammatory painkillers reduce the effect and can harm the kidneys when combined. Potassium supplements, potassium-sparing water tablets and salt substitutes can push potassium too high. Lithium levels rise when taken with these medicines. Anti-inflammatory painkillers blunt the effect and can strain the kidneys. Lithium and digoxin levels are affected; tell your doctor if you take either. Potassium-sparing types must not be combined with potassium supplements without supervision.

How to store Lotace 50-H

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Lotace 50-H

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Lotace 50-H Tablet for the treatment of high blood pressure.</li> <li><div>It can be taken with or without food.</div></li> <li><div>Lotace 50-H Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.</div></li> <li>It may cause dizziness. Get up slowly when rising from a sitting or lying position. </li> <li>Use of Lotace 50-H Tablet during pregnancy or breastfeeding is unsafe.</li> <li>It may also decrease the risk of stroke and heart attacks.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
KARNATAKA ANTIBIOTICS & PHARMA
Therapeutic class:
Anti-hypertensive and Diuretic
Drug class:
Angiotensin receptor blocker / ACE inhibitor and Water tablet

Substitutes for Lotace 50-H

Medicines with the same active ingredient (Losartan (50mg) + Hydrochlorothiazide (12.5mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lotace 50-H
Losartar HSHRRISHTI HEALTHCARE PRODUCTS(I) PVT LTD10`S₹8533% more
Zaart-H Tablet1X10₹9040% more
Cosart H Tablet1X10₹9243% more
Losanorm 50 HIPCA LABORATORIES LTD`10`S₹11579% more
Angizaar H 15S TabletMICRO LABStablet · 15`S₹248287% more
Revas HALEMBIC PHARMATABLET · 15`S₹251291% more
Losar H TabletTorrent Pharmaceuticals Ltdtablet · 15 Tablet₹281338% more
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Lotace 50-H FAQs

What is Lotace 50-H used for?
Lotace 50-H is commonly used for Lotace H Tablet is used in the treatment of high blood pressure. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lotace 50-H?
Lotace 50-H contains Losartan (50mg) + Hydrochlorothiazide (12.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lotace 50-H?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lotace 50-H work?
Lotace H Tablet is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively.
Is Lotace 50-H a prescription medicine?
Yes. Lotace 50-H is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lotace 50-H?
The side effects reported most often with Lotace 50-H are Nausea Taste change Stomach upset Diarrhea Headache Dizziness Weakness Decreased blood pressure Increased blood uric acid Increased blood lipid level Glucose intolerance Electrolyte imbalance. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lotace 50-H be taken during pregnancy?
Lotace H Tablet is unsafe to use during pregnancy.<br>There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening... Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lotace 50-H.
Can I drink alcohol while taking Lotace 50-H?
Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure.
What if I miss a dose of Lotace 50-H?
Take it as soon as you remember.
Is Lotace 50-H habit forming?
No. Lotace 50-H is not known to be habit forming when taken as prescribed.
How much does Lotace 50-H cost on PingMeDoc Pharmacy?
Lotace 50-H starts at ₹64 (MRP ₹68) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lotace 50-H?
Lotace 50-H is manufactured by KARNATAKA ANTIBIOTICS & PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lotace 50-H delivered?
Lotace 50-H is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lotace 50-H, Quick facts

Salt
Losartan (50mg) + Hydrochlorothiazide (12.5mg)
Best price
₹64
MRP
₹68
Prescription
Required (Rx)
Schedule
Schedule H
Brand
KARNATAKA ANTIBIOTICS & PHARMA
Manufacturer
KARNATAKA ANTIBIOTICS & PHARMA
Therapeutic class
Anti-hypertensive and Diuretic
Drug class
Angiotensin receptor blocker / ACE inhibitor and Water tablet
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Lotace 50-H is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lotace 50-H.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.