
Biscor 5MG Suppositories
S.S.Enterprises - 5 mg - 5 S
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Nifedipine (0.3%w/w) + Lignocaine (1.5%w/w)
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Loxheal is used for loxheal Cream is used in the treatment of piles.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Loxheal contains Nifedipine (0.3%w/w) + Lignocaine (1.5%w/w). It belongs to the Calcium channel blocker and First-aid agent class of medicines.
Loxheal Cream is used in the treatment of piles.
Loxheal Cream is a combination of two medicines: Lidocaine/Lignocaine and Nifedipine which treats piles. Lidocaine/Lignocaine is a local anesthetic. It works by blocking pain signals from the nerves to brain which decreases pain sensation. Nifedipine is a calcium channel blocker (CCB). It works in anal fissure by blocking the action of calcium on blood vessels of anus. As a result, blood vessels are relaxed which allows fissure (tear) to heal and relieves pain.
Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause a severe fall in blood pressure and a dangerously slow or irregular heartbeat. It is unlikely from external use. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Loxheal are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Loxheal Cream may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Loxheal Cream is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | Alcohol may worsen the side effects of this medicine. Limit it. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Ankle swelling is the commonest reason people stop this medicine — tell your doctor, as there are ways to manage it. Tell your doctor if your chest pain becomes more frequent or more severe after starting. Swollen, tender or overgrown gums should be reported; good brushing and regular dental care reduce the risk. For external use only, unless the pack says otherwise. See a doctor for a deep, dirty or heavily bleeding wound, an animal bite, or any wound showing signs of infection. Check that your tetanus cover is current after any dirty or penetrating wound.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with very low blood pressure or with severe narrowing of the aortic valve. Not for use on large burns or deep wounds without medical advice.
Grapefruit juice raises the level of some of these medicines in the blood — avoid it. Tell your doctor about other blood pressure medicines, and about simvastatin in particular. No significant interactions are expected.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Raising your legs when sitting, and reducing salt, helps with ankle swelling. Do not stop suddenly without asking your doctor. Clean the wound first, then apply, and keep it covered and dry.

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The information on Loxheal is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.