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Prescription requiredLupin LabCARDIAC

Lupibose 62.5

Bosentan (62.5mg)

₹1,753MRP ₹1,8455% offIn stock
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Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.

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Lupibose 62.5 is used for pulmonary arterial hypertension (PAH).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Bosentan (62.5mg)
Available variants: NA 10`S
Best price: ₹1,753
MRP: ₹1,845
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Lupibose 62.5

Lupibose 62.5 contains Bosentan (62.5mg). It belongs to the Cardiovascular agent class of medicines.

Uses of Lupibose 62.5

Pulmonary arterial hypertension (PAH)

Key benefits

  • In Pulmonary arterial hypertension (PAH) Lupibose 62.5 Tablet is used in pulmonary arterial hypertension to help lower blood pressure in the lungs. It improves exercise ability
  • reduces symptoms like shortness of breath and fatigue
  • and supports better heart and lung function over time.

How Lupibose 62.5 works

Lupibose 62.5 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. Lupibose 62.5 Tablet helps relax these blood vessels and increases the supply of blood to the lungs.

How to take Lupibose 62.5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupibose 62.5 Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Lupibose 62.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can seriously disturb the heart's rhythm and blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lupibose 62.5

Most side effects of Lupibose are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lupibose 62.5

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CAUTION
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Do not stop or change the dose of a heart medicine on your own. Report fainting, a very slow or very fast pulse, or new breathlessness. Keep every follow-up appointment — most of these medicines need periodic blood tests or an ECG.

Do not take Lupibose if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will check that this is suitable for your particular heart condition.

Interactions with other medicines

Heart medicines interact widely. Tell your doctor and pharmacist about everything you take, including herbal products.

How to store Lupibose 62.5

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Lupibose 62.5

Your doctor has prescribed Lupibose 62.5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries). It helps improve your quality of life, exercising ability, and delay disease progression. Notify your doctor if you are pregnant or planning to conceive or breastfeeding. Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver. Do not drive or do anything requiring concentration until you know how Lupibose 62.5 Tablet affects you. Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Lupibose 62.5 Tablet as it is toxic to an unborn baby. Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
CARDIAC
Drug class:
Cardiovascular agent
Chemical class:
Bipyrimidines and oligopyrimidines

Substitutes for Lupibose 62.5

Medicines with the same active ingredient (Bosentan (62.5mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lupibose 62.5
Bosentas 62.5 mg TabletCIPLA LIMITEDtablet · 10`S₹1,11736% cheaper
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Lupibose 62.5 FAQs

What is Lupibose 62.5 used for?
Lupibose 62.5 is commonly used for Pulmonary arterial hypertension (PAH). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lupibose 62.5?
Lupibose 62.5 contains Bosentan (62.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lupibose 62.5?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lupibose 62.5 work?
Lupibose 62.5 Tablet is an endothelin receptor blocker.
Is Lupibose 62.5 a prescription medicine?
Yes. Lupibose 62.5 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lupibose 62.5?
The side effects reported most often with Lupibose are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lupibose 62.5 be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lupibose.
Can I drink alcohol while taking Lupibose 62.5?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Lupibose 62.5?
If you miss a dose of Lupibose 62.5 Tablet, take it as soon as possible.
Is Lupibose 62.5 habit forming?
No. Lupibose 62.5 is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Lupibose 62.5?
Bosentas 62.5 mg Tablet has the same active ingredient and strength and is listed from ₹1,117 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Lupibose 62.5 cost on PingMeDoc Pharmacy?
Lupibose 62.5 starts at ₹1,753 (MRP ₹1,845) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lupibose 62.5?
Lupibose 62.5 is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lupibose 62.5 delivered?
Lupibose 62.5 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lupibose 62.5, Quick facts

Salt
Bosentan (62.5mg)
Best price
₹1,753
MRP
₹1,845
Prescription
Required (Rx)
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
CARDIAC
Drug class
Cardiovascular agent
Chemical class
Bipyrimidines and oligopyrimidines
Action class
Endothelin Receptor Antagonists (ERAs)
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lupibose 62.5.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.