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Prescription requiredAristo Pharmaceuticals Pvt LtdAntibiotic
Monocef-Sb 375 mg
Ceftriaxone + Sulbactam
₹88MRP ₹935% offIn stock
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Monocef-Sb 375 mg is used for this medicine is used in the treatment of bacterial infection, chest infection, urinary infection, ear and throat infection, typhoid, throat infection and skin infection.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Ceftriaxone + Sulbactam
Available variants: injection 375 mg INJ
Best price: ₹88
MRP: ₹93
Prescription: Required
Manufacturer: ARISTO PHARMACEUTICALS PVT LTD
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Monocef-Sb 375 mg
Monocef-Sb 375 mg contains Ceftriaxone + Sulbactam. It belongs to the Cephalosporin and Penicillin class of medicines.
Uses of Monocef-Sb 375 mg
- Bacterial infection
- Chest infection
- Urinary infection
- Ear
- Throat infection
- Typhoid
- Skin infection
Benefits of Monocef-Sb 375 mg
- In Bacterial infection
- Monocef-Sb kills a wide range of bacteria by breaking down their cell walls, bringing the infection under control. Finishing the full course prevents it coming back.
- In Chest infection
- Monocef-Sb treats bacterial infections of the chest, easing the cough, fever and breathlessness as the bacteria are cleared.
- In Urinary infection
- Monocef-Sb clears the bacteria behind burning, frequency and pain on passing urine.
- In Ear and throat infection
- Monocef-Sb treats bacterial infections of the ear, throat and sinuses, relieving the pain and fever they cause.
- In Typhoid
- Monocef-Sb kills the typhoid bacteria in the blood and gut, bringing down the fever and preventing the complications of untreated typhoid.
- In Throat infection
- Monocef-Sb clears the bacteria behind a sore throat or tonsillitis, so the pain, fever and difficulty swallowing settle.
- In Skin infection
- Monocef-Sb clears bacterial infections of the skin and soft tissue, bringing down the redness, swelling and pain.
How Monocef-Sb 375 mg works
This medicine combines 2 active ingredients: Ceftriaxone and Sulbactam. Ceftriaxone kills the bacteria causing your infection by destroying the cell wall that holds them together. Sulbactam kills the bacteria causing your infection by breaking down the wall they need to survive.
How to take Monocef-Sb 375 mg
This is given by a doctor or a nurse. Do not attempt to inject it yourself unless you have been trained and told to. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause vomiting, severe loose motions and, rarely, fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Monocef-Sb 375 mg
Most side effects of Monocef-Sb are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Loose motions
- Nausea
- Stomach pain
- Rash
- Thrush
- Vomiting
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Monocef-Sb 375 mg
- AlcoholCAUTION
- Alcohol may worsen the side effects of this medicine. Limit it.
- PregnancyCONSULT YOUR DOCTOR
- Consult your doctor before using this in pregnancy.
- Breast feedingCONSULT YOUR DOCTOR
- Consult your doctor before using this while breastfeeding.
- DrivingSAFE
- Not expected to affect your ability to drive.
- KidneyCONSULT YOUR DOCTOR
- Consult your doctor if you have kidney disease.
- LiverCAUTION
- Use with caution if you have liver disease. Your doctor may adjust the dose or monitor your liver function.
Warnings and precautions
Finish the whole course even after you feel better — stopping early breeds resistant bacteria. Tell your doctor if you have ever had a severe reaction to penicillin; a small proportion of people react to both groups. Report severe or watery loose motions during or after the course rather than treating them yourself. Several medicines in this group are on Schedule H1 precisely because overuse drives antibiotic resistance. Take it only when a doctor has prescribed it for you. Finish the whole course even after you feel better. Stopping early lets the strongest bacteria survive, and they are the ones that come back resistant. Stop and seek emergency care for swelling of the face or throat, difficulty breathing, or a widespread rash — a penicillin allergy can be serious. Tell every doctor and pharmacist if you have ever reacted to penicillin. Tell your doctor if loose motions become severe or watery, or continue after the course — this needs attention rather than an anti-diarrhoeal. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.
Do not take Monocef-Sb if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to cephalosporin antibiotics. Not for anyone with a known penicillin allergy.
Interactions with other medicines
Antacids, iron and zinc reduce absorption — separate them by a couple of hours. Tell your doctor if you take a blood thinner. May reduce the reliability of the oral contraceptive pill if you have vomiting or loose motions — use additional precautions during the course. Tell your doctor if you take methotrexate or a blood thinner.
How to store Monocef-Sb 375 mg
Store as printed on the carton — some injections need refrigeration and must not be frozen. Keep out of the reach of children.
Quick tips for Monocef-Sb 375 mg
- Space the doses evenly and complete the course.
- Keep the reconstituted syrup as the pharmacist instructed and discard it after the stated number of days.
- Space the doses evenly through the day so the level stays steady.
- Take a probiotic a few hours apart if loose motions trouble you, and drink plenty of fluids.
- Never use a leftover antibiotic, or someone else's, for a new illness.
Manufacturer and class
- Manufacturer:
- ARISTO PHARMACEUTICALS PVT LTD
- Therapeutic class:
- Antibiotic
- Drug class:
- Cephalosporin and Penicillin
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Monocef-Sb 375 mg FAQs
What is Monocef-Sb 375 mg used for?
Monocef-Sb 375 mg is commonly used for bacterial infection, chest infection, urinary infection, ear and throat infection, typhoid, throat infection and skin infection. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Monocef-Sb 375 mg?
Bacterial infection: Monocef-Sb kills a wide range of bacteria by breaking down their cell walls, bringing the infection under control. Finishing the full course prevents it coming back. It is also used for chest infection, urinary infection, ear and throat infection.
What is the salt in Monocef-Sb 375 mg?
Monocef-Sb 375 mg contains Ceftriaxone + Sulbactam. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Monocef-Sb 375 mg?
This is given by a doctor or a nurse. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Monocef-Sb 375 mg work?
This medicine combines 2 active ingredients: Ceftriaxone and Sulbactam.
Is Monocef-Sb 375 mg a prescription medicine?
Yes. Monocef-Sb 375 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Monocef-Sb 375 mg?
The side effects reported most often with Monocef-Sb are Loose motions, Nausea, Stomach pain, Rash, Thrush. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Monocef-Sb 375 mg be taken during pregnancy?
Consult your doctor before taking Monocef-Sb 375 mg in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Monocef-Sb.
Can I drink alcohol while taking Monocef-Sb 375 mg?
Limit alcohol while taking Monocef-Sb 375 mg; it can worsen the side effects.
What if I miss a dose of Monocef-Sb 375 mg?
Take it as soon as you remember.
Is Monocef-Sb 375 mg habit forming?
No. Monocef-Sb 375 mg is not known to be habit forming when taken as prescribed.
How much does Monocef-Sb 375 mg cost on PingMeDoc Pharmacy?
Monocef-Sb 375 mg starts at ₹88 (MRP ₹93) on PingMeDoc Pharmacy. Available in injection 375 mg INJ. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Monocef-Sb 375 mg?
Monocef-Sb 375 mg is manufactured by ARISTO PHARMACEUTICALS PVT LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Monocef-Sb 375 mg delivered?
Monocef-Sb 375 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Monocef-Sb 375 mg, Quick facts
- Salt
- Ceftriaxone + Sulbactam
- Form
- injection
- Best price
- ₹88
- MRP
- ₹93
- Prescription
- Required (Rx)
- Brand
- ARISTO PHARMACEUTICALS PVT LTD
- Manufacturer
- ARISTO PHARMACEUTICALS PVT LTD
- Therapeutic class
- Antibiotic
- Drug class
- Cephalosporin and Penicillin
- Habit forming
- No
- Variants
- injection 375 mg INJ
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Monocef-Sb 375 mg.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.