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Prescription requiredCipla LimitedAnti-emetic and Anti-ulcer agent
Neksium 20 Tablet
Domperidone (30mg) + Esomeprazole (20mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Neksium 20 Tablet is used for this medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, acidity, acid reflux, stomach ulcer and heartburn.
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Key details
Salt: Domperidone (30mg) + Esomeprazole (20mg)
Available variants: tablet 30mg + 20mg 15`S
Price: ₹165 (₹10.98 per tablet)
Prescription: Required
Manufacturer: CIPLA LIMITED
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Neksium 20 Tablet
Neksium 20 Tablet contains Domperidone (30mg) + Esomeprazole (20mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.
Uses of Neksium 20 Tablet
- Nausea
- Vomiting
- Bloating
- Slow stomach emptying
- Acidity
- Acid reflux
- Stomach ulcer
- Heartburn
Benefits of Neksium 20 Tablet
- In Nausea
- Neksium blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy.
- In Vomiting
- Neksium stops vomiting so that fluids and other medicines stay down, preventing the dehydration that repeated vomiting causes.
- In Bloating
- Neksium helps the stomach empty more quickly, easing the bloating and early fullness that follow a meal.
- In Slow stomach emptying
- Neksium strengthens the stomach's movements so food passes through more normally, relieving nausea, fullness and reflux.
- In Acidity
- Neksium switches off the pumps in the stomach lining that make acid, so there is far less acid to cause burning and discomfort.
- In Acid reflux
- Neksium reduces the acid that rises into the food pipe, relieving heartburn and giving an inflamed food pipe time to heal.
- In Stomach ulcer
- Neksium lowers stomach acid enough for an ulcer to heal and, with antibiotics when needed, helps clear the infection behind it.
- In Heartburn
- Neksium prevents the burning behind the breastbone that comes after meals or at night, so you can eat and sleep comfortably.
How Neksium 20 Tablet works
Neksium D 20 Capsules is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (ppi) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
How to take Neksium 20 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esonix-DSR Capsule is to be taken empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Neksium 20 Tablet
Most side effects of Neksium are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Dry mouth
- Drowsiness
- Headache
- Loose motions
- Restlessness
- Nausea
- Stomach pain
- Flatulence
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Neksium 20 Tablet
- AlcoholCAUTION
- Caution is advised when consuming alcohol with Neksium D 20 Capsules . Please consult your doctor.
- PregnancyUNSAFE
- Neksium D 20 Capsules may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
- Breast feedingSAFE
- Neksium D 20 Capsules is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
- DrivingCAUTION
- May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
- KidneyCAUTION
- Esonix-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Esonix-DSR Capsule may be needed. Please consult your doctor.
- LiverUNSAFE
- Esonix-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Esonix-DSR Capsule may be needed. Please consult your doctor.Use of Esonix-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Warnings and precautions
Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.
Do not take Neksium if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.
Interactions with other medicines
Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.
How to store Neksium 20 Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Quick tips for Neksium 20 Tablet
- Take it shortly before meals for bloating and early fullness.
- Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.
- Take it before breakfast, not after a meal.
- Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking.
- These do as much as the tablet for reflux.
Manufacturer and class
- Manufacturer:
- CIPLA LIMITED
- Therapeutic class:
- Anti-emetic and Anti-ulcer agent
- Drug class:
- Anti-emetic / prokinetic and Proton pump inhibitor
Substitutes for Neksium 20 Tablet
Medicines with the same active ingredient (Domperidone (30mg) + Esomeprazole (20mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Neksium 20 Tablet |
|---|---|---|---|
| Esomefa DSR Capsule | capsule · 10 | ₹130 | 21% cheaper |
| Esomac D 20 CapsuleCIPLA LIMITED | capsule · 10`S | ₹133 | 19% cheaper |
| Nexpro Rd 20 CapsuleTorrent Pharmaceuticals Ltd | capsule · 10`S | ₹147 | 11% cheaper |
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Neksium 20 Tablet FAQs
What is Neksium 20 Tablet used for?
Neksium 20 Tablet is commonly used for nausea, vomiting, bloating, slow stomach emptying, acidity, acid reflux, stomach ulcer and heartburn. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Neksium 20 Tablet?
Nausea: Neksium blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy. It is also used for vomiting, bloating, slow stomach emptying.
What is the salt in Neksium 20 Tablet?
Neksium 20 Tablet contains Domperidone (30mg) + Esomeprazole (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Neksium 20 Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Neksium 20 Tablet work?
Neksium D 20 Capsules is a combination of two medicines: Domperidone and Esomeprazole.
Is Neksium 20 Tablet a prescription medicine?
Yes. Neksium 20 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Neksium 20 Tablet?
The side effects reported most often with Neksium are Dry mouth, Drowsiness, Headache, Loose motions, Restlessness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Neksium 20 Tablet be taken during pregnancy?
Neksium 20 Tablet is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Neksium.
Can I drink alcohol while taking Neksium 20 Tablet?
Limit alcohol while taking Neksium 20 Tablet; it can worsen the side effects.
What if I miss a dose of Neksium 20 Tablet?
Take it as soon as you remember.
Is Neksium 20 Tablet habit forming?
No. Neksium 20 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Neksium 20 Tablet?
Esomefa DSR Capsule has the same active ingredient and strength and is listed from ₹130 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Neksium 20 Tablet cost on PingMeDoc Pharmacy?
Neksium 20 Tablet starts at ₹165 on PingMeDoc Pharmacy. Available in tablet 30mg + 20mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Neksium 20 Tablet?
Neksium 20 Tablet is manufactured by CIPLA LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Neksium 20 Tablet delivered?
Neksium 20 Tablet is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.
Neksium 20 Tablet, Quick facts
- Salt
- Domperidone (30mg) + Esomeprazole (20mg)
- Form
- tablet
- Price
- ₹165 (₹10.98 per tablet)
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- CIPLA LIMITED
- Manufacturer
- CIPLA LIMITED
- Therapeutic class
- Anti-emetic and Anti-ulcer agent
- Drug class
- Anti-emetic / prokinetic and Proton pump inhibitor
- Habit forming
- No
- Variants
- tablet 30mg + 20mg 15`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Neksium 20 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.