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Prescription requiredSachio Pharma Pvt LtdGASTRO INTESTINAL

Nexchio Rd Capsule

Domperidone (30mg) + Esomeprazole (40mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Blupraz-D Capsule₹71View
  • Stopflux-D Capsule₹72View
  • Esowave D Capsule₹79View

Nexchio Rd Capsule is used for treatment of Gastroesophageal reflux disease (Acid reflux).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Domperidone (30mg) + Esomeprazole (40mg)
Available variants: capsule 30mg + 40mg 10`S
Best price: ₹133 (₹13.27 per capsule)
MRP: ₹140
Prescription: Required
Manufacturer: SACHIO PHARMA PVT LTD

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Nexchio Rd Capsule.

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Nexchio Rd Capsule

capsule - 30mg + 40mg - 10 S

₹133

₹13.27 per capsule

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Nexchio Rd Capsule. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Nexchio Rd Capsule

Nexchio Rd Capsule contains Domperidone (30mg) + Esomeprazole (40mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.

Uses of Nexchio Rd Capsule

Treatment of Gastroesophageal reflux disease (Acid reflux)

Benefits of Nexchio Rd Capsule

In Nausea
Nexchio Rd blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy.
In Vomiting
Nexchio Rd stops vomiting so that fluids and other medicines stay down, preventing the dehydration that repeated vomiting causes.
In Bloating
Nexchio Rd helps the stomach empty more quickly, easing the bloating and early fullness that follow a meal.
In Slow stomach emptying
Nexchio Rd strengthens the stomach's movements so food passes through more normally, relieving nausea, fullness and reflux.
In Acidity
Nexchio Rd switches off the pumps in the stomach lining that make acid, so there is far less acid to cause burning and discomfort.
In Acid reflux
Nexchio Rd reduces the acid that rises into the food pipe, relieving heartburn and giving an inflamed food pipe time to heal.
In Stomach ulcer
Nexchio Rd lowers stomach acid enough for an ulcer to heal and, with antibiotics when needed, helps clear the infection behind it.
In Heartburn
Nexchio Rd prevents the burning behind the breastbone that comes after meals or at night, so you can eat and sleep comfortably.

How Nexchio Rd Capsule works

Nexchio RD 30mg/40mg Capsule is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic that works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and heartburn.

How to take Nexchio Rd Capsule

Take this medicine in the dose and duration as advised by your doctor. Nexchio RD 30mg/40mg Capsule is to be taken on an empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Nexchio RD 30mg/40mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Nexchio Rd Capsule

Most side effects of Nexchio Rd are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Dry mouth
  • Drowsiness
  • Headache
  • Loose motions
  • Restlessness
  • Nausea
  • Stomach pain
  • Flatulence

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Nexchio Rd Capsule

AlcoholUNSAFE
Do not drink alcohol while taking this medicine.
PregnancyCONSULT YOUR DOCTOR
Consult your doctor before using this in pregnancy.
Breast feedingUNSAFE
Not recommended while breastfeeding.
DrivingUNSAFE
Do not drive or operate machinery while taking this medicine.
KidneyCAUTION
Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
LiverUNSAFE
Not recommended if you have significant liver disease.

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.

Do not take Nexchio Rd if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.

How to store Nexchio Rd Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Nexchio Rd Capsule

  • Take Nexchio RD 30mg/40mg Capsule on an empty stomach 30 minutes to 1 hour before the meal.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Long-term use can cause weak bones and a deficiency of minerals such as magnesium.
  • Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Manufacturer and class

Manufacturer:
SACHIO PHARMA PVT LTD
Therapeutic class:
GASTRO INTESTINAL
Drug class:
Anti-emetic / prokinetic and Proton pump inhibitor

Substitutes for Nexchio Rd Capsule

Medicines with the same active ingredient (Domperidone (30mg) + Esomeprazole (40mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Nexchio Rd Capsule
Blupraz-D CapsuleBlue Cross Laboratories Pvt Ltdcapsule · 15`S₹7146% cheaper
Stopflux-D CapsuleAGARAM MEDICAL SERVICEScapsule · 10`S₹7246% cheaper
Esowave D CapsuleMEXICAN WAVE PHARMAcapsule · 10`S₹7941% cheaper
Esomefol Dsr Capsule1X10₹9032% cheaper
Esovag Dsr Capsule1₹9628% cheaper
Esomeza Dsr Capsule1X10₹1237% cheaper
Somerest D CapsuleSTATURE LIFE SCIENCES PRIVATEcapsule · 10`S₹132same price
Nexom Rd Capsule10'S₹1427% more
Sompraz D 20 CapsuleSUN PHARMAcapsule · 15 Capsules₹16927% more
Zosa Dsr CapsuleZuventus Healthcare Ltdcapsule · 15`S₹20756% more
Espra Dsr CapsuleZYDUS HEALTHCARE PHARMAcapsule · 15`S₹21562% more
Neksium D 40/30 mg CapsuleCIPLA LIMITEDcapsule · 15`S₹24081% more
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Nexchio Rd Capsule FAQs

What is Nexchio Rd Capsule used for?
Nexchio Rd Capsule is commonly used for Treatment of Gastroesophageal reflux disease (Acid reflux). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Nexchio Rd Capsule?
Nausea: Nexchio Rd blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy. It is also used for vomiting, bloating, slow stomach emptying.
What is the salt in Nexchio Rd Capsule?
Nexchio Rd Capsule contains Domperidone (30mg) + Esomeprazole (40mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Nexchio Rd Capsule?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Nexchio Rd Capsule work?
Nexchio RD 30mg/40mg Capsule is a combination of two medicines: Domperidone and Esomeprazole.
Is Nexchio Rd Capsule a prescription medicine?
Yes. Nexchio Rd Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Nexchio Rd Capsule?
The side effects reported most often with Nexchio Rd are Dry mouth, Drowsiness, Headache, Loose motions, Restlessness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Nexchio Rd Capsule be taken during pregnancy?
Consult your doctor before taking Nexchio Rd Capsule in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Nexchio Rd.
Can I drink alcohol while taking Nexchio Rd Capsule?
No. Do not drink alcohol while taking Nexchio Rd Capsule.
What if I miss a dose of Nexchio Rd Capsule?
If you miss a dose of Nexchio RD 30mg/40mg Capsule, take it as soon as possible.
Is Nexchio Rd Capsule habit forming?
No. Nexchio Rd Capsule is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Nexchio Rd Capsule?
Blupraz-D Capsule has the same active ingredient and strength and is listed from ₹71 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Nexchio Rd Capsule cost on PingMeDoc Pharmacy?
Nexchio Rd Capsule starts at ₹133 (MRP ₹140) on PingMeDoc Pharmacy. Available in capsule 30mg + 40mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Nexchio Rd Capsule?
Nexchio Rd Capsule is manufactured by SACHIO PHARMA PVT LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Nexchio Rd Capsule delivered?
Nexchio Rd Capsule is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Nexchio Rd Capsule, Quick facts

Salt
Domperidone (30mg) + Esomeprazole (40mg)
Form
capsule
Best price
₹133 (₹13.27 per capsule)
MRP
₹140
Prescription
Required (Rx)
Schedule
Schedule H
Brand
SACHIO PHARMA PVT LTD
Manufacturer
SACHIO PHARMA PVT LTD
Therapeutic class
GASTRO INTESTINAL
Drug class
Anti-emetic / prokinetic and Proton pump inhibitor
Habit forming
No
Variants
capsule 30mg + 40mg 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Nexchio Rd Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.