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Prescription requiredAlkem LabGASTRO INTESTINAL

Nuloc D Capsule

Domperidone (30mg) + Rabeprazole (20mg)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

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Nuloc D Capsule is used for treatment of Gastroesophageal reflux disease (Acid reflux).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Domperidone (30mg) + Rabeprazole (20mg)
Available variants: capsule 30mg + 20mg 10`S
Best price: ₹91 (₹9.09 per capsule)
MRP: ₹96
Prescription: Required
Manufacturer: ALKEM LAB

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

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Nuloc D Capsule

capsule - 30mg + 20mg - 10 S

₹91

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Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Nuloc D Capsule. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Nuloc D Capsule

Nuloc D Capsule contains Domperidone (30mg) + Rabeprazole (20mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.

Uses of Nuloc D Capsule

Treatment of Gastroesophageal reflux disease (Acid reflux)

Key benefits

  • In Treatment of Gastroesophageal reflux disease (Acid reflux) Gastroesophageal reflux disease (GERD) is a condition in which stomach acid flows back into the food pipe (esophagus)
  • causing symptoms like heartburn and irritation. Nuloc-D Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective. Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller
  • more frequent meals; try to lose weight if you are overweight
  • and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

How Nuloc D Capsule works

Nuloc-D Capsule SR is a combination of two medicines: Domperidone and Rabeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and heartburn.

How to take Nuloc D Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nuloc-D Capsule SR is to be taken on an empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Nuloc-D Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Nuloc D Capsule

Most side effects of Nuloc D are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Nuloc D Capsule

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.

Do not take Nuloc D if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.

How to store Nuloc D Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Nuloc D Capsule

Take Nuloc-D Capsule SR one hour before the meal, preferably in the morning. It is a well-tolerated medicine and provides relief for a long time. Inform your doctor if you experience watery diarrhea, fever, or stomach pain that persists. Inform your doctor if you do not feel better after taking it for 14 days, as you may be suffering from some other problem that needs attention. Long-term use can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor. Use Nuloc-D Capsule SR with caution if you are taking Methotrexate or certain Antiviral drugs. Always inform your doctor about these treatments so appropriate monitoring or adjustments can be made. Focus on simple eating habits such as having smaller, more frequent meals, avoiding very spicy or oily foods, and not lying down immediately after eating. Try to identify personal trigger foods, as these can vary from person to person. Maintaining a regular meal routine and a healthy weight can also help reduce symptoms over time.

Manufacturer and class

Manufacturer:
ALKEM LAB
Therapeutic class:
GASTRO INTESTINAL
Drug class:
Anti-emetic / prokinetic and Proton pump inhibitor

Substitutes for Nuloc D Capsule

Medicines with the same active ingredient (Domperidone (30mg) + Rabeprazole (20mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Nuloc D Capsule
Domisave R CapsuleCRESHA LIFESCIENCEScapsule · 10`S₹6825% cheaper
Rabesmile 20 TabletSMILECARE LIFE SCIENCEStablet · 10`S₹7617% cheaper
Rantac Rd CapsuleJB CHEMICALScapsule · 15`S₹848% cheaper
Rare D CapsuleMAAXMUS LIFE SCIENCES PVT LTDcapsule · 10`S₹857% cheaper
Rebozen Dsr Capsule10₹866% cheaper
Ulcerab Dxr CapsuleBIOCEUTICScapsule · 10`S₹866% cheaper
Zaper-Dsr CapsuleMC RIYAVIN BIORESEARCHcapsule · 10`S₹892% cheaper
Aciloc Rd 20 mg TabletCADILA PHARMAtablet · 15₹901% cheaper
Ulciwell Dsr CapsuleREDMAX PHARMAcapsule · 10`S₹921% more
Srizol-D CapsuleSKN ORGANICS (P) LTD.`capsule · 15`S₹965% more
Olez Dsr CapsuleZELLEVEN PHARMAcapsule · 10`S₹999% more
Razuur Dsr CapsuleKLM LABcapsule · 10`S₹10010% more
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Nuloc D Capsule FAQs

What is Nuloc D Capsule used for?
Nuloc D Capsule is commonly used for Treatment of Gastroesophageal reflux disease (Acid reflux). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Nuloc D Capsule?
Nuloc D Capsule contains Domperidone (30mg) + Rabeprazole (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Nuloc D Capsule?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Nuloc D Capsule work?
Nuloc-D Capsule SR is a combination of two medicines: Domperidone and Rabeprazole.
Is Nuloc D Capsule a prescription medicine?
Yes. Nuloc D Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Nuloc D Capsule?
The side effects reported most often with Nuloc D are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Nuloc D Capsule be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Nuloc D.
Can I drink alcohol while taking Nuloc D Capsule?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Nuloc D Capsule?
If you miss a dose of Nuloc-D Capsule SR, take it as soon as possible.
Is Nuloc D Capsule habit forming?
No. Nuloc D Capsule is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Nuloc D Capsule?
Domisave R Capsule has the same active ingredient and strength and is listed from ₹68 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Nuloc D Capsule cost on PingMeDoc Pharmacy?
Nuloc D Capsule starts at ₹91 (MRP ₹96) on PingMeDoc Pharmacy. Available in capsule 30mg + 20mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Nuloc D Capsule?
Nuloc D Capsule is manufactured by ALKEM LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Nuloc D Capsule delivered?
Nuloc D Capsule is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Nuloc D Capsule, Quick facts

Salt
Domperidone (30mg) + Rabeprazole (20mg)
Form
capsule
Best price
₹91 (₹9.09 per capsule)
MRP
₹96
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ALKEM LAB
Manufacturer
ALKEM LAB
Therapeutic class
GASTRO INTESTINAL
Drug class
Anti-emetic / prokinetic and Proton pump inhibitor
Habit forming
No
Variants
capsule 30mg + 20mg 10`S
Delivery
Standard across India

References

The information on Nuloc D Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Nuloc D Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.