Pregalin M SR 75

Composition of Pregalin M SR 75

Pregalin M SR 75 contains Pregabalin 75 mg (sustained release). It belongs to the Gabapentinoid (alpha-2-delta calcium channel ligand) class of medicines.

Uses of Pregalin M SR 75

• Neuropathic (nerve) pain such as diabetic peripheral neuropathy
• post-herpetic neuralgia; may also be used for other neuropathic pain conditions as prescribed

Key benefits

• Relieves neuropathic (nerve) pain
• Reduces burning/tingling sensations
• Improves sleep disturbed by nerve pain
• Sustained-release once-daily dosing convenience

How Pregalin M SR 75 works

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces release of excitatory neurotransmitters and decreases abnormal nerve signaling, thereby relieving neuropathic pain.

How to take Pregalin M SR 75

Tablet (SR): Take exactly as prescribed, usually once daily. Swallow whole with water; do not crush, chew or break. Can be taken with or without food; take at the same time each day. Do not stop suddenly—taper only on doctor’s advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Pregalin M SR as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Pregalin M SR than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Pregalin M SR 75

Most side effects of Pregalin M SR are mild and settle as the body adjusts. Reported side effects include:

• Dizziness
• sleepiness (somnolence)
• blurred vision
• dry mouth
• swelling of hands/feet (peripheral edema)
• weight gain
• fatigue
• headache
• constipation
• difficulty concentrating

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Pregalin M SR 75

Warnings and precautions

May cause dizziness and drowsiness—avoid driving/operating machinery until you know the effect. Do not stop abruptly (risk of withdrawal symptoms). Use with caution in kidney disease (dose adjustment needed), heart failure/edema, history of substance misuse, and in elderly (higher fall risk). Seek urgent help for allergic reactions/angioedema, severe skin rash, new or worsening depression/suicidal thoughts, or breathing difficulty (especially with other sedatives/opioids).

Interactions with other medicines

Alcohol, opioids (e.g., tramadol, morphine), benzodiazepines and other CNS depressants (additive drowsiness/respiratory depression), antihistamines/sedatives, ACE inhibitors (increased risk of angioedema), thiazolidinediones like pioglitazone/rosiglitazone (increased edema/weight gain)

How to store Pregalin M SR 75

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Manufacturer and class

Manufacturer:

TORRENT PHARMACEUTICALS

Therapeutic class:

Neuropathic pain analgesic

Drug class:

Gabapentinoid (alpha-2-delta calcium channel ligand)