Actibile 150 mg Tablet
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
₹286.49
Prescription required
Prescription requiredZydus Healthcare PharmaANTI DIABETIC
Siglyn M 50/500 Tablet
Sitagliptin (50mg) + Metformin (500mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Siglyn M 50/500 Tablet is used for treatment of Type 2 diabetes mellitus.
Licensed pharmacyPharmacist-verified order
Key details
Salt: Sitagliptin (50mg) + Metformin (500mg)
Available variants: tablet 50mg + 500mg 10`S
Price: ₹113 (₹11.34 per tablet)
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Siglyn M 50/500 Tablet in Bangladesh
27 brands registered in Bangladesh with the same salt, strength and form.
- Glipita M 50/500Beximco Pharmaceuticals Ltd.
- Glucodip-M XR 500Sun Pharmaceuticals (EZ) Ltd., Narayanganj
- JanmetThe ACME Laboratories Ltd.
- M-SIT XR 50/500 TABLETNIPRO JMI Pharma Limited
- MesicomVeritas Pharmaceuticals Ltd.
- N-SitametNavana Pharmaceuticals Ltd.
- Radiglip-M 50 mg/500 mgRadiant Pharmaceuticals Ltd.
- SB-Metsita 500/50Sunman-Birdem Pharma Ltd.
- SGN PlusPacific Pharmaceuticals Ltd.
- SiglimetSquare Pharmaceuticals PLC, Pabna
- Siglimet 50/500Square Lifesciences Limited, Pabna
- Siglimet 50/500 TabletSquare Pharmaceuticals PLC, Gazipur
Show all 27 brandsShow fewer
- Sigtil-MThe White Horse Pharmaceuticals Ltd.
- Silinor-M 50/500Healthcare Pharmaceuticals Ltd.
- Sitacret MRenata PLC
- Sitafit 500Team Pharmaceuticals Ltd.
- Sitagil M 500/500 ER TabIncepta Pharmaceuticals Ltd.
- Sitaglap MEuro Pharma Ltd.
- Sitalia M 500Delta Pharma PLC.
- Sitastar-M 500Goodman Pharmaceuticals Ltd
- Sitavia-M 50/500Sharif Pharmaceuticals Ltd.
- Sitazid M 50/500Eskayef Pharmaceuticals Ltd., Tongi,Gazipur
- Sitomet 50/500Advanced Chemical Industries PLC.
- Sliptin-MDrug International Ltd.
- Sliptin-M 500 ERDrug International Ltd., Gopalpur
- Sucosit-M TabletGlobe Pharmaceuticals Ltd.
- Taglimet 50/500Ibn Sina Pharmaceutical Ind. Ltd.
Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.
Compare medicine alternatives
Medicines with the same active ingredient and strength as Siglyn M 50/500 Tablet.
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Siglyn M 50/500 Tablet
tablet - 50mg + 500mg - 10 S
₹113
₹11.34 per tablet
- Galitz M 500 Tablet
SAAN LAB LLP · tablet - 500mg + 50mg - 10 S · Rx
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- Suitglip -M XR 50/500 mg Tablet
IPCA LABORATORIES LTD` · tablet - 50mg + 500mg - 10 S · Rx
₹109
₹10.85 per tablet
- Ziomet Life 50/500 Tablet
LIFELINE HEALTHCARE · tablet - 50mg + 500mg - 15 S · Rx
₹165
₹11.00 per tablet
Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Siglyn M 50/500 Tablet. The brand name, manufacturer, inactive ingredients and price can differ, and so can release form, so a substitute is not automatically interchangeable.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Siglyn M 50/500 Tablet
Siglyn M 50/500 Tablet contains Sitagliptin (50mg) + Metformin (500mg). It belongs to the DPP-4 inhibitor and Biguanide class of medicines.
Uses of Siglyn M 50/500 Tablet
Treatment of Type 2 diabetes mellitus
Benefits of Siglyn M 50/500 Tablet
- In Type 2 diabetes
- Siglyn M 50/500 strengthens the body's own after-meal insulin response, so sugar spikes after eating are smaller. It does this without pushing sugar too low on its own and without causing weight gain.
How Siglyn M 50/500 Tablet works
Siglyn M 50/500 Tablet PR is a combination of two medicines: sitagliptin and metformin. Sitagliptin helps your pancreas produce more insulin, facilitates effective use of insulin by the body, and reduces excess sugar that your liver makes. Metformin is a biguanide that lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.
How to take Siglyn M 50/500 Tablet
Use it as advised by your doctor or check the label for directions before use. Siglyn M 50/500 Tablet PR should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Siglyn M 50/500 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Siglyn M 50/500 Tablet
Most side effects of Siglyn M 50/500 are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Headache
- Sore throat
- Blocked or runny nose
- Nausea
- Stomach pain
- Loose motions
- Metallic taste
- Loss of appetite
- Flatulence
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Siglyn M 50/500 Tablet
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyUNSAFE
- Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
- Breast feedingUNSAFE
- Not recommended while breastfeeding.
- DrivingCONSULT YOUR DOCTOR
- Ask your doctor whether it is safe for you to drive on this medicine.
- KidneyCONSULT YOUR DOCTOR
- Consult your doctor if you have kidney disease.
- LiverUNSAFE
- Not recommended if you have significant liver disease.
Warnings and precautions
Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.
Do not take Siglyn M 50/500 if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Interactions with other medicines
Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.
How to store Siglyn M 50/500 Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Quick tips for Siglyn M 50/500 Tablet
- Take Siglyn M 50/500 Tablet PR with food to lower your chance of having an upset stomach.
- Take it in addition to regular exercise and a healthy diet to lower blood sugar levels.
- The chances of weight gain and low blood sugar are lower than with other diabetes medicines.
- Monitor your blood sugar level regularly while you are taking this medicine.
- Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Related lab tests
People taking Siglyn M 50/500 are often asked to check these from time to time. Your doctor decides which and how often.
Manufacturer and class
- Manufacturer:
- ZYDUS HEALTHCARE PHARMA
- Therapeutic class:
- ANTI DIABETIC
- Drug class:
- DPP-4 inhibitor and Biguanide
Substitutes for Siglyn M 50/500 Tablet
Medicines with the same active ingredient (Sitagliptin (50mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Siglyn M 50/500 Tablet |
|---|---|---|---|
| Galitz M 500 TabletSAAN LAB LLP | tablet · 10`S | ₹99 | 12% cheaper |
| Suitglip -M XR 50/500 mg TabletIPCA LABORATORIES LTD` | tablet · 10`S | ₹109 | 4% cheaper |
| Sitamax M 50/500 mg TabletAJANTA PHARMA | tablet · 10`S | ₹111 | 2% cheaper |
| Sitavas M 50/500 mg TabletCRESHA LIFESCIENCES | tablet · 10S | ₹112 | 2% cheaper |
| Ziasit 100 mg TabletSTATURE LIFE SCIENCES PRIVATE | tablet · 10`S | ₹112 | 1% cheaper |
| Macsita M XR 50/500Macleods Pharmaceuticals Pvt Ltd | 10S | ₹119 | 5% more |
| Sita OD Met 50/500 TabletMacleods Pharmaceuticals Pvt Ltd | tablet · 10`S | ₹120 | 6% more |
| Alsita M 50 TabletALKEM LAB | tablet · 10`S | ₹121 | 7% more |
| Sita OD Msr 100/500 TabletMacleods Pharmaceuticals Pvt Ltd | tablet · 10`S | ₹128 | 13% more |
| Sitaearth M 500 TabletD EARTH PHARMACEUTICALS | tablet · 10`S | ₹134 | 18% more |
| Ziomet Life 50/500 TabletLIFELINE HEALTHCARE | tablet · 15`S | ₹165 | 45% more |
| Sugaray - M 50/500 mg TabletLLOYD HEALTHCARE | tablet · 15`S | ₹168 | 48% more |
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Siglyn M 50/500 Tablet FAQs
What is Siglyn M 50/500 Tablet used for?
Siglyn M 50/500 Tablet is commonly used for Treatment of Type 2 diabetes mellitus. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Siglyn M 50/500 Tablet?
Type 2 diabetes: Siglyn M 50/500 strengthens the body's own after-meal insulin response, so sugar spikes after eating are smaller. It does this without pushing sugar too low on its own and without causing weight gain.
What is the salt in Siglyn M 50/500 Tablet?
Siglyn M 50/500 Tablet contains Sitagliptin (50mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Siglyn M 50/500 Tablet?
Use it as advised by your doctor or check the label for directions before use. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Siglyn M 50/500 Tablet work?
Siglyn M 50/500 Tablet PR is a combination of two medicines: sitagliptin and metformin.
Is Siglyn M 50/500 Tablet a prescription medicine?
Yes. Siglyn M 50/500 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Siglyn M 50/500 Tablet?
The side effects reported most often with Siglyn M 50/500 are Headache, Sore throat, Blocked or runny nose, Nausea, Stomach pain. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Siglyn M 50/500 Tablet be taken during pregnancy?
Siglyn M 50/500 Tablet is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Siglyn M 50/500.
Can I drink alcohol while taking Siglyn M 50/500 Tablet?
No. Do not drink alcohol while taking Siglyn M 50/500 Tablet.
What if I miss a dose of Siglyn M 50/500 Tablet?
If you miss a dose of Siglyn M 50/500 Tablet PR, take it as soon as possible.
Is Siglyn M 50/500 Tablet habit forming?
No. Siglyn M 50/500 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Siglyn M 50/500 Tablet?
Galitz M 500 Tablet has the same active ingredient and strength and is listed from ₹99 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Siglyn M 50/500 Tablet cost on PingMeDoc Pharmacy?
Siglyn M 50/500 Tablet starts at ₹113 on PingMeDoc Pharmacy. Available in tablet 50mg + 500mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Siglyn M 50/500 Tablet?
Siglyn M 50/500 Tablet is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Siglyn M 50/500 Tablet delivered?
Siglyn M 50/500 Tablet is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.
Siglyn M 50/500 Tablet, Quick facts
- Salt
- Sitagliptin (50mg) + Metformin (500mg)
- Form
- tablet
- Price
- ₹113 (₹11.34 per tablet)
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- ZYDUS HEALTHCARE PHARMA
- Manufacturer
- ZYDUS HEALTHCARE PHARMA
- Therapeutic class
- ANTI DIABETIC
- Drug class
- DPP-4 inhibitor and Biguanide
- Habit forming
- No
- Variants
- tablet 50mg + 500mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Siglyn M 50/500 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.