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Icarus Healthcare - Tablet - 200mg + 200mg - 10 S
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Prescription required
Glucosamine (750mg) + Diacerein (50mg) + Methyl Sulfonyl Methane (200mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Spon 50 is used for spon 50 Tablet is used in the treatment of osteoarthritis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Spon 50 contains Glucosamine (750mg) + Diacerein (50mg) + Methyl Sulfonyl Methane (200mg). It belongs to the Vitamin and mineral supplement and Non-steroidal anti-inflammatory drug class of medicines.
Spon 50 Tablet is used in the treatment of osteoarthritis.
Spon 50 Tablet is a combination of three medicines: Glucosamine, Diacerein and Methyl Sulfonyl Methane, which treats osteoarthritis. Glucosamine and Diacerein are proteoglycan synthesis stimulators while Methyl Sulfonyl Methane (MSM) is a nutritional supplement. Together, they help in the building of cartilage (the soft tissue around the joints) leading to joint repair. MSM additionally lowers inflammation (swelling) of the joints.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spon 50 Tablet is to be taken with food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting and stomach pain, and with iron can be dangerous, especially in children. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Spon are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Unknown. Human and animal studies are not available. Please consult your doctor. |
|---|---|
| Breastfeeding | No information is available on the use of Spon 50 Tablet during lactation. Please consult your doctor. |
| Alcohol | Interaction with alcohol is unknown. Please consult your doctor. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Spon 50 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Spon 50 Tablet may not be needed in these patients. Please consult your doctor. |
| Liver | Spon 50 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor. |
| Habit forming | No |
A supplement is not a substitute for a balanced diet or for treating the cause of a symptom. Iron makes stools black and can cause constipation — this is expected, but tell your doctor if it troubles you. Keep iron-containing products well out of reach of children; an overdose in a small child is a medical emergency. Check the labels of everything you take so you do not double up on the same nutrient. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Iron, calcium, zinc and magnesium reduce the absorption of thyroid tablets and several antibiotics — separate them by a few hours. Tea and coffee taken with iron reduce how much is absorbed; vitamin C increases it. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it with food unless the pack says otherwise. Have deficiencies confirmed and rechecked by blood test rather than supplementing indefinitely. Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.

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The information on Spon 50 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.