Toujeo 300U/ML Cartridge Injection

Composition of Toujeo 300U/ML Cartridge Injection

Toujeo 300U/ML Cartridge Injection contains Insulin glargine 300 units/mL (U-300) solution for injection. It belongs to the Long-acting insulin analogue (basal insulin) class of medicines.

Uses of Toujeo 300U/ML Cartridge Injection

Treatment of diabetes mellitus to improve glycaemic control in adults; used as a long-acting (basal) insulin in type 1 diabetes (with mealtime insulin) and type 2 diabetes (alone or with other antidiabetic medicines) as prescribed.

Key benefits

• Provides 24-hour basal insulin coverage
• Helps control fasting blood glucose
• Once-daily dosing for many patients
• Reduces risk of hyperglycaemia when used regularly
• Supports overall HbA1c control as part of diabetes management

How Toujeo 300U/ML Cartridge Injection works

Insulin glargine is a long-acting insulin analogue. After subcutaneous injection, it forms a depot in the tissue and is slowly released, providing a steady basal insulin level that lowers blood glucose by increasing peripheral glucose uptake and reducing hepatic glucose production.

How to take Toujeo 300U/ML Cartridge Injection

For subcutaneous use only. Inject once daily at the same time each day (as advised by the doctor) into abdomen, thigh or upper arm; rotate injection sites. Do not inject into a vein or muscle and do not mix/dilute with other insulins. Follow prescribed dose and titration based on blood glucose; use the compatible insulin pen/device for Toujeo cartridges as instructed.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Toujeo 300U/ML Cartridge as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Toujeo 300U/ML Cartridge than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Toujeo 300U/ML Cartridge Injection

Most side effects of Toujeo 300U/ML Cartridge are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia (low blood sugar)
• injection site reactions (pain
• redness
• swelling
• itching)
• weight gain
• lipodystrophy (skin thickening or pitting at injection site)
• rash
• peripheral oedema

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Toujeo 300U/ML Cartridge Injection

Warnings and precautions

Risk of hypoglycaemia—monitor blood glucose regularly and carry fast-acting sugar. Use caution in renal/hepatic impairment, elderly, irregular meals, increased exercise, or alcohol use. Do not use during episodes of hypoglycaemia. Not for treatment of diabetic ketoacidosis (use short-acting insulin). Switching from other insulins should be done under medical supervision (dose differences between U-100 and U-300). Seek urgent care for severe allergic reaction. Use proper injection technique and site rotation to reduce lipodystrophy.

Interactions with other medicines

Other antidiabetic drugs (additive hypoglycaemia),ACE inhibitors/ARBs (may increase hypoglycaemia risk),beta-blockers (may mask hypoglycaemia symptoms),corticosteroids/thyroid hormones/sympathomimetics (may increase blood glucose),thiazide diuretics (may increase blood glucose),alcohol (can increase risk of hypoglycaemia),pioglitazone/other TZDs (risk of fluid retention/heart failure when used with insulin)

How to store Toujeo 300U/ML Cartridge Injection

Store unopened cartridges refrigerated at 2–8°C; do not freeze and keep away from freezer compartment. Protect from light; keep in outer carton. After first use, keep at room temperature (do not refrigerate) below 30°C, away from heat/light, and use within the period stated on the label/device instructions; do not use if solution is cloudy or contains particles.

Manufacturer and class

Manufacturer:

SANOFI INDIA LTD

Therapeutic class:

Antidiabetic

Drug class:

Long-acting insulin analogue (basal insulin)