Zensita Trio 1000 Tab 15S

Composition

Metformin (1000mg) + Dapagliflozin (10mg) + Sitagliptin (100mg)

Uses of Zensita Trio 1000 Tab 15S

Type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control when triple therapy is appropriate.

• •Lowers fasting and post-meal blood glucose
• •Improves HbA1c control with triple mechanism
• •Low risk of hypoglycaemia when not combined with insulin/secretagogues
• •May support modest weight loss with SGLT2 inhibitor
• •Convenient once-daily regimen (XR)

How it works

Metformin reduces glucose production by the liver and improves insulin sensitivity. Sitagliptin (a DPP-4 inhibitor) increases incretin levels, enhancing insulin release and reducing glucagon after meals. Dapagliflozin (an SGLT2 inhibitor) increases urinary glucose excretion by blocking glucose reabsorption in the kidneys.

Directions for use

Oral tablet; take exactly as prescribed. Usually taken once daily with food (preferably with the main meal) and swallowed whole (do not crush/chew) if extended-release. Maintain adequate hydration and follow diet/exercise advice; monitor blood glucose as advised.

Side effects

Common side effects of Zensita Trio 1000 Tab 15S may include:

• •Nausea
• •diarrhoea
• •abdominal discomfort