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Dr Reddys Laboratories Ltd - Tablet - 10 S
Prescription required
Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml)
Zyrcold Dc Syrup is used for symptomatic relief of dry (non-productive) cough associated with common cold/allergy, runny nose, sneezing, nasal congestion and throat irritation.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Zyrcold Dc Syrup contains Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml). It belongs to the Antitussive + Antihistamine (H1 blocker) + Nasal decongestant (alpha-adrenergic agonist) class of medicines.
Dextromethorphan suppresses the cough reflex by acting on the cough center in the brain. Phenylephrine is a nasal decongestant that constricts swollen nasal blood vessels to relieve blockage. Chlorpheniramine is an antihistamine that reduces sneezing, runny nose and watery eyes.
Oral syrup; take as prescribed by a doctor. Measure with a dosing cup/spoon; usually taken 2–3 times daily. Can be taken with or without food; take after food if stomach upset occurs. Do not exceed recommended dose and avoid use for more than a few days unless advised.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Zyrcold DC Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Zyrcold Dc than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Zyrcold Dc are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Avoid |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
May cause marked drowsiness—avoid driving or operating machinery. Do not use with/within 14 days of MAO inhibitors. Use with caution in hypertension, heart disease, thyroid disorder, diabetes, glaucoma, enlarged prostate/urinary retention, liver disease, asthma/COPD. Not recommended in children unless prescribed; overdose can be serious. Seek medical advice if cough persists >7 days, is accompanied by fever/rash, or if breathing difficulty occurs.
MAO inhibitors (serious reactions), SSRIs/SNRIs/TCAs/linezolid/triptans (risk of serotonin syndrome with dextromethorphan), other sedatives/CNS depressants (increased drowsiness), antihypertensives (reduced effect), other decongestants/sympathomimetics (increased BP/heart rate), anticholinergics (increased dryness/urinary retention)
Store below 25°C, protected from light and moisture. Keep bottle tightly closed. Keep out of reach of children.
Take Zyrcold DC Syrup only for the duration advised by your doctor, usually until symptoms improve. Drink plenty of fluids to soothe throat irritation and help relieve symptoms, but Zyrcold DC Syrup should not be used for cough with mucus. Zyrcold DC Syrup may cause drowsiness, so avoid driving or operating machinery until you know how it affects you. Avoid alcohol or other sedative medicines while taking Zyrcold DC Syrup, as they may increase sleepiness. Dry mouth may occur; staying hydrated and including fiber in your diet may help. Avoid combining Zyrcold DC Syrup with other cough or cold medicines unless advised by your doctor. Use with caution if you have high blood pressure or heart disease. Stop and consult your doctor if you experience palpitations or severe headache. Stop taking Zyrcold DC Syrup and seek medical help if you develop rash, facial swelling, or difficulty breathing. Consult your doctor if cough lasts more than one week, keeps recurring, or is accompanied by fever, rash, or persistent headache. Do not take Zyrcold DC Syrup with antidepressants or similar medicines without consulting your doctor, as it may cause serious side effects.
Medicines with the same active ingredient (Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Zyrcold Dc Syrup |
|---|---|---|---|
| Tuscus SyrupHIBISCUS PHARMACEUTICALS PRIVA | syrup · 60ML | ₹78 | 32% more |
| Alex DropsGLENMARK PHARMACEUTICALS | drop · 15ML | ₹82 | 38% more |
| Ambrolite D SyrupTablets India Limited | syrup · 60 Ml | ₹89 | 51% more |
| Pcf SyrupJACSIMS PHARMACEUTICALS | syrup · 100ML | ₹98 | 67% more |
| Ascoril D Junior Cough SyrupGLENMARK PHARMACEUTICALS | syrup · 60 Ml | ₹117 | 98% more |
| Mucopex D SuspensionWALFS PHARMA | suspension · 100ML | ₹131 | 122% more |
| Ascoril D Plus Sugar Free SyrupGLENMARK PHARMACEUTICALS | syrup · 100 Ml | ₹169 | 186% more |

Dr Reddys Laboratories Ltd - Tablet - 10 S
Prescription required
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Prescription required

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The information on Zyrcold Dc Syrup is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.