
Active Retinol Intense Age 1%
Skinnovation - 30 ml
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Retinol 0.5% w/v (in topical serum/solution base)
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Active Retinol 0.5% is used for helps improve signs of photoageing (fine lines, wrinkles), uneven skin tone and texture; supports acne-prone skin by helping prevent comedones; promotes smoother, brighter-looking skin.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Active Retinol 0.5% contains Retinol 0.5% w/v (in topical serum/solution base). It belongs to the Topical retinoid (vitamin A derivative/keratolytic) class of medicines.
Retinol (vitamin A derivative) is converted in skin to retinoic acid, which increases cell turnover and supports collagen synthesis. It helps reduce comedone formation, improves texture, and gradually fades pigmentation and photoageing changes.
For external use only. Apply a pea-sized amount as a thin layer to clean, dry face at night; start 2-3 nights/week and increase as tolerated. Use moisturizer if needed; apply broad-spectrum sunscreen (SPF 30+) every morning. Avoid applying on broken/irritated skin and avoid eye/lip corners.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting, stomach pain and, with some minerals, damage over the longer term. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Active Retinol 0.5% are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Patch test before use. Avoid use on eczematous, sunburnt, or broken skin. Reduce frequency or stop if severe irritation occurs. Do not combine the same night with other strong irritants/exfoliants (AHA/BHA/peels) unless advised. Avoid waxing/laser/abrasive procedures on treated areas due to irritation risk. Use sunscreen daily; limit sun exposure. Keep out of reach of children. Consult a dermatologist if you have very sensitive skin, rosacea, or are using prescription retinoids.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Increased irritation with AHAs/BHAs (glycolic/salicylic), benzoyl peroxide (can inactivate/irritate—separate timing), other retinoids (tretinoin/adapalene/isotretinoin), abrasive scrubs, alcohol-based toners, chemical peels; photosensitizing agents may increase sun sensitivity.
Store below 25°C in a cool, dry place away from direct sunlight and heat. Keep container tightly closed; do not freeze.
People taking Active Retinol 0.5% are often asked to check these from time to time. Your doctor decides which and how often.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.