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Torrent Pharmaceuticals Ltd - 100 G
Furosemide (20mg) + Spironolactone (50mg)
Amifru-S Tablet is used for treatment of Resistant Hypertension (high blood pressure) Treatment of Chronic Heart Failure Treatment of Liver cirrhosis with edema.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Amifru-S Tablet contains Furosemide (20mg) + Spironolactone (50mg).
Treatment of Resistant Hypertension (high blood pressure) Treatment of Chronic Heart Failure Treatment of Liver cirrhosis with edema
Amifru-S Tablet contains two medicines: furosemide and spironolactone, which act on different parts of the kidney to remove excess fluid. Furosemide is a short-acting loop diuretic that helps the kidneys eliminate sodium, chloride, and water through urine, thereby reducing fluid overload and blood pressure. Spironolactone is a long-acting aldosterone antagonist that promotes the excretion of sodium and water while conserving potassium, helping maintain electrolyte balance and preventing potassium loss during treatment.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amifru-S Tablet should be taken with or after food. Avoid Amifru-S Tablet with dietary sodium.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Amifru-S Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Amifru-S than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Amifru-S are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol CONSULT YOUR DOCTOR |
| Driving | Driving UNSAFE |
| Kidney | Kidney UNSAFE |
| Liver | Liver CAUTION |
| Habit forming | No |
Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Amifru-S. Some combinations can change how Amifru-S works or raise the chance of side effects.
Store Amifru-S below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.
Amifru-S Tablet helps remove excess water from your body. Take it in the morning with breakfast to avoid getting up at night to urinate. It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away. Your doctor may regularly monitor your blood pressure, kidney function, and the level of salts such as potassium and sodium in your blood while you're taking this medication.
Medicines with the same active ingredient (Furosemide (20mg) + Spironolactone (50mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Amifru-S Tablet |
|---|---|---|---|
| Lasilactone 50 TabletSANOFI INDIA LTD | tablet · 10 Tablet | ₹65 | 100% more |

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The information on Amifru-S Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.