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Prescription requiredAristo Pharmaceuticals Pvt LtdCARDIAC

Amlosafe LS 2.5/2.5

Amlodipine (2.5mg) + Lisinopril (2.5mg)

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Amlosafe LS 2.5/2.5 is used for angina (heart-related chest pain) Treatment of Hypertension (high blood pressure) Arrhythmia Hypertensive emergency Subarachnoid haemorrhage Anal fissure.

Licensed pharmacyPharmacist-verified order

Key details

Salt: Amlodipine (2.5mg) + Lisinopril (2.5mg)
Available variants: NA 10`S
Price: ₹40
Prescription: Required
Manufacturer: ARISTO PHARMACEUTICALS PVT LTD

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Amlosafe LS 2.5/2.5

Amlosafe LS 2.5/2.5 contains Amlodipine (2.5mg) + Lisinopril (2.5mg). It belongs to the Calcium channel blocker and Angiotensin receptor blocker / ACE inhibitor class of medicines.

Uses of Amlosafe LS 2.5/2.5

Angina (heart-related chest pain) Treatment of Hypertension (high blood pressure) Arrhythmia Hypertensive emergency Subarachnoid haemorrhage Anal fissure

Benefits of Amlosafe LS 2.5/2.5

In High blood pressure
Amlosafe LS 2.5/2.5 relaxes the muscle in the walls of your arteries so blood flows with less pressure. Keeping blood pressure down protects you from stroke, heart attack and kidney damage over the years.
In Angina
Amlosafe LS 2.5/2.5 widens the vessels that supply the heart and eases its workload, so you get fewer episodes of chest pain and can do more before pain comes on.
In Heart failure
Amlosafe LS 2.5/2.5 eases the load on a weak heart so it pumps more efficiently, which reduces breathlessness and swelling and lowers the chance of a hospital admission.
In Diabetic kidney disease
Amlosafe LS 2.5/2.5 reduces the pressure inside the kidneys' filters and cuts the protein leaking into the urine, slowing the kidney damage that diabetes causes.

How Amlosafe LS 2.5/2.5 works

Amlosafe 2.5 Tablet is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. In heart-related chest pain (angina), the enhanced blood flow in the body relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.

How to take Amlosafe LS 2.5/2.5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlosafe 2.5 Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Amlosafe 2.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

If you take too much

An overdose of this medicine can cause a severe fall in blood pressure and a dangerously slow or irregular heartbeat. It can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Amlosafe LS 2.5/2.5

Most side effects of Amlosafe LS 2.5/2.5 are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Swelling of the ankles and feet
  • Flushing
  • Headache
  • Palpitations
  • Dizziness
  • Tiredness
  • Dizziness on standing up
  • Raised potassium
  • Dry cough

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Amlosafe LS 2.5/2.5

AlcoholCAUTION
Alcohol may worsen the side effects of this medicine. Limit it.
PregnancyUNSAFE
Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCONSULT YOUR DOCTOR
Consult your doctor if you have kidney disease.
LiverCAUTION
Use with caution if you have liver disease. Your doctor may adjust the dose or monitor your liver function.

Warnings and precautions

Ankle swelling is the commonest reason people stop this medicine — tell your doctor, as there are ways to manage it. Tell your doctor if your chest pain becomes more frequent or more severe after starting. Swollen, tender or overgrown gums should be reported; good brushing and regular dental care reduce the risk. Stand up slowly for the first few days — dizziness on rising is common when you start or your dose goes up. Stop and seek urgent care if your lips, tongue, face or throat swell, or you have difficulty breathing. A persistent dry, tickly cough can be caused by the ACE inhibitor group; tell your doctor rather than stopping on your own, as an alternative exists. Your doctor will check your kidney function and potassium after starting and after any dose change. Do not use salt substitutes containing potassium without asking your doctor.

Do not take Amlosafe LS 2.5/2.5 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with very low blood pressure or with severe narrowing of the aortic valve. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines.

Interactions with other medicines

Grapefruit juice raises the level of some of these medicines in the blood — avoid it. Tell your doctor about other blood pressure medicines, and about simvastatin in particular. Anti-inflammatory painkillers reduce the effect and can harm the kidneys when combined. Potassium supplements, potassium-sparing water tablets and salt substitutes can push potassium too high. Lithium levels rise when taken with these medicines.

How to store Amlosafe LS 2.5/2.5

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Amlosafe LS 2.5/2.5

  • You have been prescribed Amlosafe 2.5 Tablet to improve your blood pressure and/or to reduce the number and severity of angina attacks.
  • Lowering blood pressure reduces the chance of future heart attack and stroke.
  • Take it at the same time every day to help you remember to take it.
  • A sudden drop in your blood pressure may occur, especially when you first start taking Amlosafe 2.5 Tablet.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling.
  • To reduce the swelling, raise your legs while you are sitting down.
  • Talk to your doctor if it does not go away.

People taking Amlosafe LS 2.5/2.5 are often asked to check these from time to time. Your doctor decides which and how often.

Manufacturer and class

Manufacturer:
ARISTO PHARMACEUTICALS PVT LTD
Therapeutic class:
CARDIAC
Drug class:
Calcium channel blocker and Angiotensin receptor blocker / ACE inhibitor
Chemical class:
Dihydropyridine carboxylic acid derivative

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Amlosafe LS 2.5/2.5 FAQs

What is Amlosafe LS 2.5/2.5 used for?
Amlosafe LS 2.5/2.5 is commonly used for Angina (heart-related chest pain) Treatment of Hypertension (high blood pressure) Arrhythmia Hypertensive emergency Subarachnoid haemorrhage Anal fissure. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Amlosafe LS 2.5/2.5?
High blood pressure: Amlosafe LS 2.5/2.5 relaxes the muscle in the walls of your arteries so blood flows with less pressure. Keeping blood pressure down protects you from stroke, heart attack and kidney damage over the years. It is also used for angina, heart failure, diabetic kidney disease.
What is the salt in Amlosafe LS 2.5/2.5?
Amlosafe LS 2.5/2.5 contains Amlodipine (2.5mg) + Lisinopril (2.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Amlosafe LS 2.5/2.5?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Amlosafe LS 2.5/2.5 work?
Amlosafe 2.5 Tablet is a calcium channel blocker.
Is Amlosafe LS 2.5/2.5 a prescription medicine?
Yes. Amlosafe LS 2.5/2.5 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Amlosafe LS 2.5/2.5?
The side effects reported most often with Amlosafe LS 2.5/2.5 are Swelling of the ankles and feet, Flushing, Headache, Palpitations, Dizziness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Amlosafe LS 2.5/2.5 be taken during pregnancy?
Amlosafe LS 2.5/2.5 is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Amlosafe LS 2.5/2.5.
Can I drink alcohol while taking Amlosafe LS 2.5/2.5?
Limit alcohol while taking Amlosafe LS 2.5/2.5; it can worsen the side effects.
What if I miss a dose of Amlosafe LS 2.5/2.5?
If you miss a dose of Amlosafe 2.5 Tablet, take it as soon as possible.
Is Amlosafe LS 2.5/2.5 habit forming?
No. Amlosafe LS 2.5/2.5 is not known to be habit forming when taken as prescribed.
How much does Amlosafe LS 2.5/2.5 cost on PingMeDoc Pharmacy?
Amlosafe LS 2.5/2.5 starts at ₹40 on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Amlosafe LS 2.5/2.5?
Amlosafe LS 2.5/2.5 is manufactured by ARISTO PHARMACEUTICALS PVT LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Amlosafe LS 2.5/2.5 delivered?
Amlosafe LS 2.5/2.5 is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.

Amlosafe LS 2.5/2.5, Quick facts

Salt
Amlodipine (2.5mg) + Lisinopril (2.5mg)
Price
₹40
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ARISTO PHARMACEUTICALS PVT LTD
Manufacturer
ARISTO PHARMACEUTICALS PVT LTD
Therapeutic class
CARDIAC
Drug class
Calcium channel blocker and Angiotensin receptor blocker / ACE inhibitor
Chemical class
Dihydropyridine carboxylic acid derivative
Action class
Calcium Channel Blockers- Dihydropyridines (DHP)
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Amlosafe LS 2.5/2.5.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.