Dapaone S 10/100

Composition of Dapaone S 10/100

Dapaone S 10/100 contains Dapagliflozin 10 mg + Sitagliptin 100 mg (tablet). It belongs to the SGLT2 inhibitor + DPP-4 inhibitor class of medicines.

Uses of Dapaone S 10/100

• Type 2 diabetes mellitus to improve blood sugar control (as an add-on to diet and exercise)
• especially when dual therapy is required

Key benefits

• Lowers fasting and post-meal blood glucose
• Provides dual complementary mechanism for better HbA1c control
• Low risk of hypoglycaemia when used without insulin/sulfonylurea
• May support modest weight loss with dapagliflozin
• Once-daily convenient dosing

How Dapaone S 10/100 works

Dapagliflozin is an SGLT2 inhibitor that increases urinary glucose excretion by reducing glucose reabsorption in the kidneys. Sitagliptin is a DPP-4 inhibitor that increases incretin levels, enhancing insulin release and reducing glucagon in a glucose-dependent manner.

How to take Dapaone S 10/100

Take as prescribed by the doctor, usually once daily by mouth. Can be taken with or without food; take at the same time each day and swallow whole with water. Maintain adequate hydration and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Dapaone S 10/100

Most side effects of Dapaone S 10/100 are mild and settle as the body adjusts. Reported side effects include:

• Genital fungal infection
• urinary tract infection
• increased urination
• thirst
• headache
• nasopharyngitis
• nausea
• diarrhea
• dizziness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Dapaone S 10/100

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Risk of dehydration and low blood pressure; drink fluids and use caution in elderly or those on diuretics. SGLT2 inhibitors can rarely cause ketoacidosis (even with near-normal sugar), serious urinary infections, and Fournier’s gangrene—seek urgent care if symptoms occur. Monitor kidney function; effectiveness reduces with significant renal impairment and may not be recommended at low eGFR. Sitagliptin may rarely cause pancreatitis or severe joint pain; stop and seek medical advice if severe abdominal pain occurs. Risk of hypoglycaemia increases if used with insulin or sulfonylureas; dose adjustment may be needed.

Do not take Dapaone S 10/100 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension risk), rifampicin and other strong enzyme inducers (may reduce sitagliptin exposure), digoxin (sitagliptin may increase levels—monitor), alcohol (increases dehydration/ketoacidosis risk)

How to store Dapaone S 10/100

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Dapaone S 10/100

Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them.

Manufacturer and class

Manufacturer:

MSN LABORATORIES

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + DPP-4 inhibitor