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Prescription requiredLupin LtdRESPIRATORY

Esiflo 125 Transhaler

Salmeterol (25mcg) + Fluticasone Propionate (125mcg)

Esiflo 125 Transhaler is used for treatment of Asthma Treatment of Chronic obstructive pulmonary disease (COPD).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹637MRP ₹70810% off
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Salmeterol (25mcg) + Fluticasone Propionate (125mcg)
Available variants: inhale 120 MDI
Best price: ₹637
MRP: ₹708
Prescription: Required
Manufacturer: Lupin Ltd

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Esiflo 125 Transhaler

Esiflo 125 Transhaler contains Salmeterol (25mcg) + Fluticasone Propionate (125mcg). It belongs to the Inhaled bronchodilator / corticosteroid class of medicines.

Uses of Esiflo 125 Transhaler

Treatment of Asthma Treatment of Chronic obstructive pulmonary disease (COPD)

Key benefits

  • In Treatment of Asthma Esiflo Hfa 125 Transhaler can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust
  • pollen
  • pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing
  • coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms. In Treatment of Chronic obstructive pulmonary disease (COPD) Esiflo Hfa 125 Transhaler helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest
  • shortness of breath
  • wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor. Show More

How Esiflo 125 Transhaler works

Esiflo Hfa 125 Transhaler is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

How to take Esiflo 125 Transhaler

Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Esiflo Hfa 125 Transhaler, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esiflo 125 Transhaler

Most side effects of Esiflo are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esiflo 125 Transhaler

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CAUTION
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving UNSAFE
KidneyKidney
LiverLiver
Habit formingNo

Warnings and precautions

Know which of your inhalers is the reliever and which is the preventer. A preventer must be used every day even when you feel well; a reliever is for symptoms. Seek emergency care if your reliever is not working, if you cannot speak a full sentence, or if you are using the reliever far more often than usual. Rinse your mouth with water and spit it out after every steroid inhaler dose to prevent thrush and hoarseness. Ask your doctor or pharmacist to watch your technique — poor technique is the commonest reason an inhaler seems not to work. Use a spacer if one has been advised, particularly for children.

Do not take Esiflo if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.

Interactions with other medicines

Beta blockers, including eye drops for glaucoma, can tighten the airways and reduce the effect of your reliever.

How to store Esiflo 125 Transhaler

Store below 30°C, away from direct sunlight and heat. Do not puncture or burn the canister, even when empty. Keep out of the reach of children.

Expert advice for Esiflo 125 Transhaler

This medicine is for inhalation only. The tablet should not be swallowed. It should be taken at the same time each day. It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help. Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat. Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using. Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Esiflo Hfa 125 Transhaler can lower blood potassium level. Only miniscule amounts of Esiflo Hfa 125 Transhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Manufacturer and class

Manufacturer:
Lupin Ltd
Therapeutic class:
RESPIRATORY
Drug class:
Inhaled bronchodilator / corticosteroid

Substitutes for Esiflo 125 Transhaler

Medicines with the same active ingredient (Salmeterol (25mcg) + Fluticasone Propionate (125mcg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Esiflo 125 Transhaler
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Esiflo 125 Transhaler FAQs

What is Esiflo 125 Transhaler used for?
Esiflo 125 Transhaler is commonly used for Treatment of Asthma Treatment of Chronic obstructive pulmonary disease (COPD). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Esiflo 125 Transhaler?
Esiflo 125 Transhaler contains Salmeterol (25mcg) + Fluticasone Propionate (125mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Esiflo 125 Transhaler?
Check the label for directions before use. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Esiflo 125 Transhaler work?
Esiflo Hfa 125 Transhaler is a combination of two medicines: Salmeterol and Fluticasone Propionate.
Is Esiflo 125 Transhaler a prescription medicine?
Yes. Esiflo 125 Transhaler is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Esiflo 125 Transhaler?
The side effects reported most often with Esiflo are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Esiflo 125 Transhaler be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Esiflo.
Can I drink alcohol while taking Esiflo 125 Transhaler?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Esiflo 125 Transhaler?
If you miss a dose of Esiflo Hfa 125 Transhaler, use it as soon as possible.
Is Esiflo 125 Transhaler habit forming?
No. Esiflo 125 Transhaler is not known to be habit forming when taken as prescribed.
How much does Esiflo 125 Transhaler cost on PingMeDoc Pharmacy?
Esiflo 125 Transhaler starts at ₹637 (MRP ₹708) on PingMeDoc Pharmacy. Available in inhale 120 MDI. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Esiflo 125 Transhaler?
Esiflo 125 Transhaler is manufactured by Lupin Ltd. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Esiflo 125 Transhaler delivered?
Esiflo 125 Transhaler is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Esiflo 125 Transhaler, Quick facts

Salt
Salmeterol (25mcg) + Fluticasone Propionate (125mcg)
Form
inhale
Best price
₹637
MRP
₹708
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Lupin Ltd
Manufacturer
Lupin Ltd
Therapeutic class
RESPIRATORY
Drug class
Inhaled bronchodilator / corticosteroid
Habit forming
No
Variants
inhale 120 MDI
Delivery
Standard across India

References

The information on Esiflo 125 Transhaler is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Esiflo 125 Transhaler.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.