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Drs Choice Pharmaceuticals - Tablet - 10 S
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Glimepiride 2 mg + Metformin Hydrochloride 500 mg (modified/extended release)
Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.
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Glimefort-M2 Tablet is used for type 2 diabetes mellitus (adult) to control high blood sugar when diet and exercise alone are not sufficient.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Glimefort-M2 Tablet contains Glimepiride 2 mg + Metformin Hydrochloride 500 mg (modified/extended release). It belongs to the Sulfonylurea + Biguanide class of medicines.
Type 2 diabetes mellitus (adult) to control high blood sugar when diet and exercise alone are not sufficient
Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, helping the body use glucose better.
Oral tablet. Take exactly as prescribed, usually once daily with/after a main meal (preferably breakfast). Swallow whole; do not crush/chew if modified/extended-release. Monitor blood glucose regularly and follow diet/exercise advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Glimefort-M2 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended / Consult doctor (insulin preferred in pregnancy) |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Prescription-only antidiabetic. Risk of hypoglycaemia (especially with missed meals, alcohol, heavy exercise, or with other antidiabetics); carry glucose. Metformin may rarely cause lactic acidosis—risk higher in kidney impairment, dehydration, severe infection, heart/respiratory failure, alcohol use; assess renal function before and during therapy. Hold metformin before/after iodinated contrast procedures and major surgery as advised. Use caution in elderly and in liver disease. Not for type 1 diabetes or diabetic ketoacidosis.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Alcohol (increases hypoglycaemia and lactic acidosis risk),insulin/other antidiabetics (additive hypoglycaemia),ACE inhibitors (may enhance glucose-lowering),beta-blockers (mask hypoglycaemia symptoms),corticosteroids/thiazide diuretics/sympathomimetics (raise blood glucose),rifampicin (reduces glimepiride effect),fluconazole/azoles (increase sulfonylurea effect),iodinated contrast media (metformin—lactic acidosis risk)
Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.
Medicines with the same active ingredient (Glimepiride 2 mg + Metformin Hydrochloride 500 mg (modified/extended release)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Glimefort-M2 Tablet |
|---|---|---|---|
| Glimefort-M2 Pro TabletDRS CHOICE PHARMACEUTICALS | tablet · 10`S | ₹80 | 35% more |
| Glimiact M2 TabletMIRTH PHARMACEUTICALS | tablet · 10`S | ₹95 | 60% more |
| Glimigrand M2 TabletD EARTH PHARMACEUTICALS | tablet · 15`S | ₹137 | 131% more |

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.