
Advastat 10MG Tab
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Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (15mg)
Glynamic Mp1 Tablet is used for glynamic MP1 Tablet is used in the treatment of type 2 diabetes.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Glynamic Mp1 Tablet contains Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (15mg). It belongs to the Sulfonylurea, Biguanide and Oral anti-diabetic class of medicines.
Glynamic MP1 Tablet is used in the treatment of type 2 diabetes.
Glynamic MP1 Tablet is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glynamic MP1 Tablet is to be taken with food.<br>Glynamic MP1 Tablet may cause stomach upset if taken empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Glynamic Mp1 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Glynamic MP1 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Glynamic MP1 Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.<br>Monitor the breastfed baby’s blood sugar during treatment with Glynamic MP1 Tablet |
| Alcohol | It is unsafe to consume alcohol with Glynamic MP1 Tablet . |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Glynamic MP1 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glynamic MP1 Tablet may be needed. Please consult your doctor.<br>Use of Glynamic MP1 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. |
| Liver | Glynamic MP1 Tablet should be used with caution in patients with liver disease. Dose adjustment of Glynamic MP1 Tablet may be needed. Please consult your doctor.<br>Use of Glynamic MP1 Tablet is not recommended in patients with severe liver disease. |
| Habit forming | No |
If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. If a low-sugar episode happens while on an alpha-glucosidase inhibitor such as voglibose or acarbose, use glucose — ordinary sugar and sweets work more slowly. Tell your doctor about any new swelling of the ankles, breathlessness or sudden weight gain.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.
Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when combined with insulin or a sulfonylurea.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>Glynamic MP1 Tablet ER is a combination of three medicines that provides better blood sugar control than either medicine alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glynamic MP1 Tablet ER.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li><div>Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.</div></li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (15mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Glynamic Mp1 Tablet |
|---|---|---|---|
| Debistal gm Tablet | 1X10 | ₹90 | 23% cheaper |
| Triglimiprex 1 TabletARISTO PHARMACEUTICALS PVT LTD | tablet · 10`S | ₹131 | 11% more |

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The information on Glynamic Mp1 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.