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Prescription requiredSun Pharmaceutical Industries LtdAnti-diabetic

Istamet 50/500 Tablet

Metformin (500mg) + Sitagliptin (50mg)

₹171In stock
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Delivered across India. ₹49 delivery, free above ₹999.

This medicine needs a prescription.

You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.

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A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.

Istamet 50/500 Tablet is used for controls blood sugar levels, prevents complications, easy to take.

  • Original brandsFrom authorised distributors or the brand's own supply chain.

  • The price on the packYou pay the printed MRP. No inflated MRPs, no fake strike-throughs.

  • Licensed pharmacyPrescription medicines are checked by our pharmacist before packing.

  • 7 days to report a problemReport a wrong or damaged item within 7 days of delivery and our team reviews a return.

Key details

Salt: Metformin (500mg) + Sitagliptin (50mg)
Available variants: tablet 15 Tablet, tablet 15 Tablet 15 Tablet
Price: ₹171 (₹11.40 per tablet)
Prescription: Required
Manufacturer: Sun Pharmaceutical Industries Ltd

Ordering notes

Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Istamet 50/500 Tablet in Bangladesh

27 brands registered in Bangladesh with the same salt, strength and form.

  • Glipita M 50/500Beximco Pharmaceuticals Ltd.
  • Glucodip-M XR 500Sun Pharmaceuticals (EZ) Ltd., Narayanganj
  • JanmetThe ACME Laboratories Ltd.
  • M-SIT XR 50/500 TABLETNIPRO JMI Pharma Limited
  • MesicomVeritas Pharmaceuticals Ltd.
  • N-SitametNavana Pharmaceuticals Ltd.
  • Radiglip-M 50 mg/500 mgRadiant Pharmaceuticals Ltd.
  • SB-Metsita 500/50Sunman-Birdem Pharma Ltd.
  • SGN PlusPacific Pharmaceuticals Ltd.
  • SiglimetSquare Pharmaceuticals PLC, Pabna
  • Siglimet 50/500Square Lifesciences Limited, Pabna
  • Siglimet 50/500 TabletSquare Pharmaceuticals PLC, Gazipur
Show all 27 brands
  • Sigtil-MThe White Horse Pharmaceuticals Ltd.
  • Silinor-M 50/500Healthcare Pharmaceuticals Ltd.
  • Sitacret MRenata PLC
  • Sitafit 500Team Pharmaceuticals Ltd.
  • Sitagil M 500/500 ER TabIncepta Pharmaceuticals Ltd.
  • Sitaglap MEuro Pharma Ltd.
  • Sitalia M 500Delta Pharma PLC.
  • Sitastar-M 500Goodman Pharmaceuticals Ltd
  • Sitavia-M 50/500Sharif Pharmaceuticals Ltd.
  • Sitazid M 50/500Eskayef Pharmaceuticals Ltd., Tongi,Gazipur
  • Sitomet 50/500Advanced Chemical Industries PLC.
  • Sliptin-MDrug International Ltd.
  • Sliptin-M 500 ERDrug International Ltd., Gopalpur
  • Sucosit-M TabletGlobe Pharmaceuticals Ltd.
  • Taglimet 50/500Ibn Sina Pharmaceutical Ind. Ltd.

Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.

Compare medicine alternatives

Medicines with the same active ingredient and strength as Istamet 50/500 Tablet.

You are viewing

Istamet 50/500 Tablet

tablet - 15 Tablet

₹171

₹11.40 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Istamet 50/500 Tablet. The brand name, manufacturer, inactive ingredients and price can differ, and so can release form, so a substitute is not automatically interchangeable.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Istamet 50/500 Tablet

Istamet 50/500 Tablet contains Metformin (500mg) + Sitagliptin (50mg). It belongs to the Biguanide and DPP-4 inhibitor class of medicines.

Uses of Istamet 50/500 Tablet

  • Controls blood sugar levels
  • Prevents complications
  • Easy to take

Benefits of Istamet 50/500 Tablet

In Type 2 diabetes
Istamet 50/500 lowers the amount of sugar your liver releases and helps your body use its own insulin, so blood sugar stays in a steadier range through the day. Keeping sugar controlled over the years protects the eyes, kidneys, nerves and heart from the damage diabetes causes.

How Istamet 50/500 Tablet works

Decreases hepatic glucose production and improves insulin sensitivity; acts in liver and gut.

How to take Istamet 50/500 Tablet

Take as directed by the physician, with or after food. Swallow it whole. Do not chew, crush, or break it.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Istamet 50/500 Tablet

Most side effects of Istamet 50/500 are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • GI upset (nausea, diarrhea)
  • rare risk of lactic acidosis

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Istamet 50/500 Tablet

Alcohol
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
PregnancyCONSULT YOUR DOCTOR
Istamet 50mg/500mg Tablet is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Breast feedingSAFE
Istamet 50mg/500mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
DrivingSAFE
Not expected to affect your ability to drive.
KidneyUNSAFE
Istamet 50mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Istamet 50mg/500mg Tablet may be needed. Please consult your doctor.Use of Istamet 50mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
LiverCONSULT YOUR DOCTOR
Istamet 50mg/500mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Istamet 50mg/500mg Tablet may not be needed in these patients. Please consult your doctor.

Warnings and precautions

Inform clinician about kidney problems; withhold around iodinated contrast when advised.

Do not take Istamet 50/500 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis.

Interactions with other medicines

Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.

How to store Istamet 50/500 Tablet

Store below 25°C; protect from moisture.

Quick tips for Istamet 50/500 Tablet

  • Your doctor may check your kidney and liver function before starting treatment and regularly thereafter.
  • Inform your doctor if you develop symptoms such as abdominal pain, fatigue, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.

People taking Istamet 50/500 are often asked to check these from time to time. Your doctor decides which and how often.

Manufacturer and class

Manufacturer:
Sun Pharmaceutical Industries Ltd
Therapeutic class:
Anti-diabetic
Drug class:
Biguanide and DPP-4 inhibitor

Substitutes for Istamet 50/500 Tablet

Medicines with the same active ingredient (Metformin (500mg) + Sitagliptin (50mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Istamet 50/500 Tablet
Galitz M 500 TabletSAAN LAB LLPtablet · 10`S₹9942% cheaper
Suitglip -M XR 50/500 mg TabletIPCA LABORATORIES LTD`tablet · 10`S₹10937% cheaper
Sitamax M 50/500 mg TabletAJANTA PHARMAtablet · 10`S₹11135% cheaper
Sitavas M 50/500 mg TabletCRESHA LIFESCIENCEStablet · 10S₹11235% cheaper
Ziasit 100 mg TabletSTATURE LIFE SCIENCES PRIVATEtablet · 10`S₹11235% cheaper
Macsita M XR 50/500Macleods Pharmaceuticals Pvt Ltd10S₹11931% cheaper
Sita OD Met 50/500 TabletMacleods Pharmaceuticals Pvt Ltdtablet · 10`S₹12030% cheaper
Alsita M 50 TabletALKEM LABtablet · 10`S₹12129% cheaper
Sita OD Msr 100/500 TabletMacleods Pharmaceuticals Pvt Ltdtablet · 10`S₹12825% cheaper
Sitaearth M 500 TabletD EARTH PHARMACEUTICALStablet · 10`S₹13422% cheaper
Ziomet Life 50/500 TabletLIFELINE HEALTHCAREtablet · 15`S₹1654% cheaper
Sugaray - M 50/500 mg TabletLLOYD HEALTHCAREtablet · 15`S₹1682% cheaper
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Istamet 50/500 Tablet FAQs

What is Istamet 50/500 Tablet used for?
Istamet 50/500 Tablet is commonly used for controls blood sugar levels, prevents complications, easy to take. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Istamet 50/500 Tablet?
Type 2 diabetes: Istamet 50/500 lowers the amount of sugar your liver releases and helps your body use its own insulin, so blood sugar stays in a steadier range through the day. Keeping sugar controlled over the years protects the eyes, kidneys, nerves and heart from the damage diabetes causes.
What is the salt in Istamet 50/500 Tablet?
Istamet 50/500 Tablet contains Metformin (500mg) + Sitagliptin (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Istamet 50/500 Tablet?
Take as directed by the physician, with or after food. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Istamet 50/500 Tablet work?
Decreases hepatic glucose production and improves insulin sensitivity; acts in liver and gut.
Is Istamet 50/500 Tablet a prescription medicine?
Yes. Istamet 50/500 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Istamet 50/500 Tablet?
The side effects reported most often with Istamet 50/500 are GI upset (nausea, diarrhea), rare risk of lactic acidosis. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Istamet 50/500 Tablet be taken during pregnancy?
Consult your doctor before taking Istamet 50/500 Tablet in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Istamet 50/500.
Can I drink alcohol while taking Istamet 50/500 Tablet?
Ask your doctor before drinking alcohol while on Istamet 50/500 Tablet.
What if I miss a dose of Istamet 50/500 Tablet?
Take it as soon as you remember.
Is Istamet 50/500 Tablet habit forming?
No. Istamet 50/500 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Istamet 50/500 Tablet?
Galitz M 500 Tablet has the same active ingredient and strength and is listed from ₹99 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Istamet 50/500 Tablet cost on PingMeDoc Pharmacy?
Istamet 50/500 Tablet starts at ₹171 on PingMeDoc Pharmacy. Available in tablet 15 Tablet, tablet 15 Tablet 15 Tablet. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Istamet 50/500 Tablet?
Istamet 50/500 Tablet is manufactured by Sun Pharmaceutical Industries Ltd. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Istamet 50/500 Tablet delivered?
Istamet 50/500 Tablet is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.

Istamet 50/500 Tablet, Quick facts

Salt
Metformin (500mg) + Sitagliptin (50mg)
Form
tablet
Price
₹171 (₹11.40 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Sun Pharmaceutical Industries Ltd
Manufacturer
Sun Pharmaceutical Industries Ltd
Therapeutic class
Anti-diabetic
Drug class
Biguanide and DPP-4 inhibitor
Habit forming
No
Variants
tablet 15 Tablet, tablet 15 Tablet 15 Tablet
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Istamet 50/500 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.