Istamet D Ir 5/50/1000

Composition

Dapagliflozin 5 mg + Sitagliptin 50 mg + Metformin Hydrochloride 1000 mg (Immediate-release) per tablet

Uses of Istamet D Ir 5/50/1000

Type 2 diabetes mellitus: to improve glycaemic control as an adjunct to diet and exercise when treatment with these medicines is appropriate.

• •Helps reduce fasting and post-meal blood sugar
• •Improves insulin sensitivity and lowers glucose production
• •Promotes glucose removal via urine
• •Low risk of hypoglycaemia when used without insulin/secretagogues
• •May support weight and blood pressure reduction due to SGLT2 action

How it works

Metformin decreases hepatic glucose production and improves insulin sensitivity. Sitagliptin (a DPP-4 inhibitor) increases incretin levels, enhancing glucose-dependent insulin release and reducing glucagon. Dapagliflozin (an SGLT2 inhibitor) increases urinary glucose excretion by blocking glucose reabsorption in the kidney.

Directions for use

Oral tablet (IR). Take as prescribed by your doctor, usually with meals to reduce stomach upset. Swallow whole with water; do not crush/chew. Maintain adequate hydration; follow diet/exercise advice and monitor blood glucose.

Side effects

Common side effects of Istamet D Ir 5/50/1000 may include:

• •Nausea
• •diarrhoea
• •