
8X Cream
Cipla Limited - Cream - 1%W/W - 30 G
Save ₹12.66
Prescription required
Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Lumacip Plus Cream is used for melasma.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Lumacip Plus Cream contains Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w). It belongs to the Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor class of medicines.
Melasma
Lumacip Plus Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Lumacip Plus Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. It can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Lumacip Plus are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds. Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.
No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Medicines with the same active ingredient (Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Lumacip Plus Cream |
|---|---|---|---|
| Triluma CreamGALDERMA INDIA PVT LTD | cream · 15GM | ₹820 | 398% more |

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Prescription required

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.