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Prescription requiredCipla LimitedDERMA

Lumacip Plus Cream

Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w)

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Lumacip Plus Cream is used for melasma.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w)
Available variants: cream 4%w/w + 0.05%w/w + 0.01%w/w 15GM
Best price: ₹165 (₹10.98 per g)
MRP: ₹173
Prescription: Required
Manufacturer: CIPLA LIMITED

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Lumacip Plus Cream

Lumacip Plus Cream contains Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w). It belongs to the Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor class of medicines.

Uses of Lumacip Plus Cream

Melasma

Benefits of Lumacip Plus Cream

In Skin conditions
Lumacip Plus treats the skin condition it was prescribed for, relieving itch, redness, dryness or infection so the skin can recover.
In Skin care
Lumacip Plus protects, soothes and maintains the skin as part of a daily routine.
In Acne
Lumacip Plus unblocks pores, reduces the bacteria and inflammation behind spots and helps prevent new ones forming. Improvement is gradual over several weeks.
In Blackheads and whiteheads
Lumacip Plus clears the blocked pores that form blackheads and whiteheads and keeps new ones from forming.
In Pigmentation
Lumacip Plus lightens dark marks left behind by spots, sun exposure or hormonal changes, evening out the skin tone over weeks of regular use.
In Rough skin
Lumacip Plus smooths rough, uneven skin by speeding up the shedding of dead surface cells.
In Eczema
Lumacip Plus calms the inflammation behind an eczema flare, quickly reducing the redness, itch and weeping so the skin can heal and the scratch-itch cycle is broken.
In Dermatitis
Lumacip Plus settles the red, itchy, inflamed skin of dermatitis, whether from an allergy, irritant or contact with something the skin reacts to.
In Psoriasis
Lumacip Plus reduces the thickening, scaling and redness of psoriasis plaques and relieves the itch.
In Skin inflammation and itching
Lumacip Plus relieves itching and inflammation of the skin from insect bites, rashes and reactions, so the skin can settle.

How Lumacip Plus Cream works

Lumacip Plus Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.

How to take Lumacip Plus Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Lumacip Plus Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. It can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lumacip Plus Cream

Most side effects of Lumacip Plus are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Local irritation
  • Redness
  • Itching
  • Dryness
  • Peeling
  • Burning or stinging
  • Increased sensitivity to sunlight
  • Thinning of the skin
  • Stretch marks
  • Acne
  • Change in skin colour

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lumacip Plus Cream

AlcoholCAUTION
Alcohol may worsen the side effects of this medicine. Limit it.
PregnancyUNSAFE
Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
Breast feedingUNSAFE
Not recommended while breastfeeding.
DrivingSAFE
Not expected to affect your ability to drive.
KidneyCAUTION
Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
LiverCONSULT YOUR DOCTOR
Consult your doctor if you have liver disease.

Warnings and precautions

For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds. Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted.

Do not take Lumacip Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.

How to store Lumacip Plus Cream

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Quick tips for Lumacip Plus Cream

  • Along with applying Lumacip Plus Cream, wear long-sleeved clothing, sunglasses, or a hat whenever you step outside in the hot sun for better protection.
  • Do not cover the area being treated with airtight dressings unless instructed by a doctor.
  • Use moisturizer regularly to overcome skin dryness during the course of treatment.
  • You may also use certain safe cosmetics (after consulting with your doctor) to lighten pigmentation.
  • Before using Lumacip Plus Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.

Manufacturer and class

Manufacturer:
CIPLA LIMITED
Therapeutic class:
DERMA
Drug class:
Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor

Substitutes for Lumacip Plus Cream

Medicines with the same active ingredient (Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lumacip Plus Cream
Triluma CreamGALDERMA INDIA PVT LTDcream · 15GM₹820398% more
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Lumacip Plus Cream FAQs

What is Lumacip Plus Cream used for?
Lumacip Plus Cream is commonly used for Melasma. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Lumacip Plus Cream?
Skin conditions: Lumacip Plus treats the skin condition it was prescribed for, relieving itch, redness, dryness or infection so the skin can recover. It is also used for skin care, acne, blackheads and whiteheads.
What is the salt in Lumacip Plus Cream?
Lumacip Plus Cream contains Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lumacip Plus Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lumacip Plus Cream work?
Lumacip Plus Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin).
Is Lumacip Plus Cream a prescription medicine?
Yes. Lumacip Plus Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lumacip Plus Cream?
The side effects reported most often with Lumacip Plus are Local irritation, Redness, Itching, Dryness, Peeling. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lumacip Plus Cream be taken during pregnancy?
Lumacip Plus Cream is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lumacip Plus.
Can I drink alcohol while taking Lumacip Plus Cream?
Limit alcohol while taking Lumacip Plus Cream; it can worsen the side effects.
What if I miss a dose of Lumacip Plus Cream?
If you miss a dose of Lumacip Plus Cream, apply it as soon as possible.
Is Lumacip Plus Cream habit forming?
No. Lumacip Plus Cream is not known to be habit forming when taken as prescribed.
How much does Lumacip Plus Cream cost on PingMeDoc Pharmacy?
Lumacip Plus Cream starts at ₹165 (MRP ₹173) on PingMeDoc Pharmacy. Available in cream 4%w/w + 0.05%w/w + 0.01%w/w 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lumacip Plus Cream?
Lumacip Plus Cream is manufactured by CIPLA LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lumacip Plus Cream delivered?
Lumacip Plus Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lumacip Plus Cream, Quick facts

Salt
Hydroquinone (4% w/w) + Tretinoin (0.05% w/w) + Fluocinolone acetonide (0.01% w/w)
Form
cream
Best price
₹165 (₹10.98 per g)
MRP
₹173
Prescription
Required (Rx)
Brand
CIPLA LIMITED
Manufacturer
CIPLA LIMITED
Therapeutic class
DERMA
Drug class
Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor
Habit forming
No
Variants
cream 4%w/w + 0.05%w/w + 0.01%w/w 15GM
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lumacip Plus Cream.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.