Macpril H 2.5

Composition of Macpril H 2.5

Macpril H 2.5 contains Ramipril (2.5mg) + Hydrochlorothiazide (12.5mg). It belongs to the Angiotensin receptor blocker / ACE inhibitor and Water tablet class of medicines.

Uses of Macpril H 2.5

Macpril H 2.5 Tablet is used in the treatment of high blood pressure.

Key benefits

• Protects the kidneys in diabetes
• Reduces the long-term risk of stroke and heart attack
• Usually taken once a day
• Relieves swelling and breathlessness caused by fluid
• Long-established blood pressure treatment
• Inexpensive and once daily

How Macpril H 2.5 works

Macpril H 2.5 Tablet is a combination of two medicines: Ramipril and hydrochlorothiazide which lower blood pressure effectively. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

How to take Macpril H 2.5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macpril H 2.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. It can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Macpril H 2.5

Most side effects of Macpril H are mild and settle as the body adjusts. Reported side effects include:

• Nausea Indigestion Taste change Diarrhea Stomach pain Headache Dizziness Weakness Glucose intolerance Increased uric acid level in blood Increased blood lipid level Electrolyte imbalance Cough Decreased blood pressure

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Macpril H 2.5

Warnings and precautions

Stand up slowly for the first few days — dizziness on rising is common when you start or your dose goes up. Stop and seek urgent care if your lips, tongue, face or throat swell, or you have difficulty breathing. A persistent dry, tickly cough can be caused by the ACE inhibitor group; tell your doctor rather than stopping on your own, as an alternative exists. Your doctor will check your kidney function and potassium after starting and after any dose change. Do not use salt substitutes containing potassium without asking your doctor. Take it in the morning so that passing urine does not disturb your sleep. Your doctor will check your salts and kidney function with blood tests — do not skip them. Report muscle cramps, marked weakness, confusion or an irregular heartbeat; these can be signs your potassium or sodium has fallen. In hot weather or during an illness with vomiting or loose motions, tell your doctor — you may become dehydrated quickly.

Do not take Macpril H if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Anti-inflammatory painkillers reduce the effect and can harm the kidneys when combined. Potassium supplements, potassium-sparing water tablets and salt substitutes can push potassium too high. Lithium levels rise when taken with these medicines. Anti-inflammatory painkillers blunt the effect and can strain the kidneys. Lithium and digoxin levels are affected; tell your doctor if you take either. Potassium-sparing types must not be combined with potassium supplements without supervision.

How to store Macpril H 2.5

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Macpril H 2.5

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Ramipres-H Tablet for the treatment of high blood pressure.</li> <li>It also lowers your risk of stroke and heart attack.</li> <li>Take it in the morning with breakfast, to avoid getting up at night to urinate.</li> <li>Ramipres-H Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.</li> <li>To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.</li> <li>Inform you doctor about any cough, or throat irritation that doesn't go away.</li> <li>Ramipres-H Tablet may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.</li> <li>Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.</li> <li>Do not take Ramipres-H Tablet if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:

MACLEODS PHARMACEUTICALS LTD

Therapeutic class:

Anti-hypertensive and Diuretic

Drug class:

Angiotensin receptor blocker / ACE inhibitor and Water tablet