Met XL D 50/10 mg Tablet

Composition of Met XL D 50/10 mg Tablet

Met XL D 50/10 mg Tablet contains Metoprolol succinate (extended-release) 50 mg + Amlodipine 10 mg. It belongs to the Beta-blocker (beta-1 selective) + Calcium channel blocker (dihydropyridine) class of medicines.

Uses of Met XL D 50/10 mg Tablet

Treatment of hypertension (high blood pressure); may be used in patients requiring combination therapy to control BP and reduce cardiovascular risk.

Key benefits

• Lowers high blood pressure
• Helps prevent complications of hypertension (stroke/heart attack risk reduction)
• Controls heart rate and reduces cardiac workload
• Improves blood vessel relaxation and blood flow

How Met XL D 50/10 mg Tablet works

Metoprolol is a beta-1 selective beta blocker that slows heart rate and reduces the force of contraction, lowering blood pressure. Amlodipine is a calcium channel blocker that relaxes blood vessels by inhibiting calcium entry into vascular smooth muscle, improving blood flow and reducing BP.

How to take Met XL D 50/10 mg Tablet

Tablet for oral use. Take exactly as prescribed, preferably at the same time each day. Swallow whole with water; do not crush/chew (extended-release). Can be taken with or without food. Do not stop abruptly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. It can cause a severe fall in blood pressure and a dangerously slow or irregular heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Met XL D 50/10 mg Tablet

Most side effects of Met XL D 50/10 mg are mild and settle as the body adjusts. Reported side effects include:

• Dizziness
• fatigue
• headache
• slow heart rate (bradycardia)
• low blood pressure
• ankle/feet swelling (edema)
• flushing
• palpitations
• nausea
• constipation

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Met XL D 50/10 mg Tablet

Warnings and precautions

Prescription medicine. Do not stop metoprolol suddenly (risk of chest pain/heart attack in susceptible patients). Use with caution in asthma/COPD (may worsen breathing), diabetes (may mask low-sugar symptoms), thyroid disorders, peripheral vascular disease, and in patients with slow heart rate/heart block or heart failure unless supervised. Monitor BP and pulse. Amlodipine may cause ankle swelling and dizziness. Caution while driving if dizzy. Inform doctor before surgery/anesthesia.

Do not take Met XL D 50/10 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma. Not for people with very low blood pressure or with severe narrowing of the aortic valve.

Interactions with other medicines

Other antihypertensives (additive BP lowering), verapamil/diltiazem/digoxin/antiarrhythmics (risk of bradycardia/heart block), clonidine (rebound hypertension on withdrawal), NSAIDs (may reduce antihypertensive effect), CYP3A4 inhibitors like clarithromycin/azoles/grapefruit (increase amlodipine levels), CYP3A4 inducers like rifampicin/phenytoin/carbamazepine (reduce amlodipine effect), alcohol (increases dizziness/hypotension)

How to store Met XL D 50/10 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Met XL D 50/10 mg Tablet

Take it at the same time each day and do not miss doses. Learn to check your own pulse, and report a persistently slow one. Raising your legs when sitting, and reducing salt, helps with ankle swelling. Do not stop suddenly without asking your doctor.

Manufacturer and class

Manufacturer:

AJANTA PHARMA

Therapeutic class:

Antihypertensive

Drug class:

Beta-blocker (beta-1 selective) + Calcium channel blocker (dihydropyridine)