Metolar XR 12.5

Composition of Metolar XR 12.5

Metolar XR 12.5 contains Metoprolol succinate extended-release 12.5 mg (per tablet). It belongs to the Cardioselective beta-blocker (beta-1 adrenergic blocker) class of medicines.

Uses of Metolar XR 12.5

• Hypertension (high blood pressure)
• angina (chest pain)
• chronic stable heart failure (as adjunct therapy)
• rate control in certain tachyarrhythmias; may be used for secondary prevention after myocardial infarction as per physician advice

Key benefits

• Lowers blood pressure
• Reduces angina episodes
• Helps control heart rate
• Improves symptoms/outcomes in stable chronic heart failure
• Provides 24-hour control with once-daily dosing

How Metolar XR 12.5 works

Metoprolol is a cardioselective beta-1 adrenergic blocker. It reduces heart rate and contractility, lowering blood pressure and myocardial oxygen demand. The XR formulation releases medicine slowly to provide 24-hour control.

How to take Metolar XR 12.5

Take by mouth once daily at the same time each day, with or without food. Swallow the extended-release tablet whole; do not crush/chew/split unless advised. Dose is individualized; do not stop suddenly without medical supervision.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Metolar XR 12.5

Most side effects of Metolar XR are mild and settle as the body adjusts. Reported side effects include:

• Tiredness
• dizziness
• slow heart rate (bradycardia)
• low blood pressure
• headache
• nausea
• cold hands/feet
• sleep disturbances

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Metolar XR 12.5

Warnings and precautions

Do not stop abruptly (may worsen angina/trigger heart attack). Use with caution in asthma/COPD (may cause bronchospasm), diabetes (may mask hypoglycaemia symptoms), thyroid disorders, peripheral vascular disease, liver impairment, and in patients with low heart rate/heart block. Contraindicated in severe bradycardia, second/third-degree AV block, cardiogenic shock, and acute decompensated heart failure unless directed by a specialist. Monitor pulse and blood pressure regularly.

Do not take Metolar XR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma.

Interactions with other medicines

Other antihypertensives (additive hypotension), calcium channel blockers like verapamil/diltiazem (risk of bradycardia/heart block), antiarrhythmics (e.g., amiodarone), digoxin, clonidine (rebound hypertension if stopped improperly), NSAIDs (may reduce antihypertensive effect), CYP2D6 inhibitors such as fluoxetine/paroxetine/quinidine (may increase metoprolol levels), insulin/oral antidiabetics (masked hypoglycaemia)

How to store Metolar XR 12.5

Store at room temperature (below 25°C), protected from moisture and light. Keep in original blister pack and out of reach of children.

Expert advice for Metolar XR 12.5

Take it at the same time each day and do not miss doses. Learn to check your own pulse, and report a persistently slow one.

Manufacturer and class

Manufacturer:

CIPLA LIMITED

Therapeutic class:

Antihypertensive, Antianginal, Heart failure therapy

Drug class:

Cardioselective beta-blocker (beta-1 adrenergic blocker)