
Betamil-Gm
Procter & Gamble Health Ltd - 30 G
Prescription required
Vitamin D3 (200IU/5ml) + Cyanocobalamin (2.5mcg/5ml) + Calcium (210mg/5ml)
Osto-Polybion Syrup is used for this medicine is used in the treatment of vitamin d deficiency, low calcium, osteoporosis, bone health, vitamin b deficiency, nerve pain and tingling, anaemia and tiredness due to deficiency.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Osto-Polybion Syrup contains Vitamin D3 (200IU/5ml) + Cyanocobalamin (2.5mcg/5ml) + Calcium (210mg/5ml). It belongs to the Vitamin D / calcium supplement and B-complex vitamin class of medicines.
This medicine combines 3 active ingredients: Vitamin d, Methylcobalamin and Calcium. Vitamin d helps your gut absorb calcium and keeps the mineral level in your blood and bones where it should be. Methylcobalamin replaces a B vitamin your body needs to make red blood cells, to keep nerves healthy and to release energy from food. Calcium helps your gut absorb calcium and keeps the mineral level in your blood and bones where it should be.
Shake the bottle well before each dose and measure it with the cup, spoon or dropper supplied — a kitchen spoon is not an accurate measure. Take it with food. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can raise blood calcium dangerously, causing thirst, frequent urination, vomiting, confusion and kidney damage. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Osto-Polybion are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Generally considered safe in pregnancy. Tell your doctor if you are pregnant or planning to be. |
|---|---|
| Breastfeeding | Generally considered safe while breastfeeding. |
| Alcohol | Alcohol may worsen the side effects of this medicine. Limit it. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | No dose change is usually needed in liver disease. |
| Habit forming | No |
Do not take more than your doctor has advised. Vitamin D builds up in the body and too much raises blood calcium, causing thirst, frequent urination, nausea and confusion. High-dose weekly or monthly sachets are prescription strengths — do not repeat one because you missed a week. Tell your doctor if you have had kidney stones or have kidney disease. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a high blood calcium level, or with certain kidney stones.
Calcium reduces the absorption of thyroid tablets, several antibiotics and iron — separate them by a few hours. Water tablets of the thiazide group raise calcium further when combined. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.
Store below 30°C, away from direct sunlight. Do not freeze. Once opened, use it within the period printed on the pack. Keep out of the reach of children.
Take calcium with food, and split the day's total if you take a large amount. Sunlight helps your body make its own vitamin D. Have your level rechecked as your doctor advises rather than continuing high doses indefinitely. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.

Procter & Gamble Health Ltd - 30 G
Prescription required
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Prescription required

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Prescription required
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Prescription required

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Prescription required

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Prescription required
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Prescription required

East West Pharma - Tablet - 10 mg - 10 S
Prescription required
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Prescription required

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Prescription required

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Prescription required
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Prescription required

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Prescription required

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Prescription required
The information on Osto-Polybion Syrup is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.