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Prescription requiredR.b.pharmaceuticalsNeuropathic pain agent, Antidepressant and Vitamin supplement
Remethyl Pro Vanilla
Pregabalin (75mg) + Nortriptyline (10mg) + Mecobalamin (1500mcg)
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹237
Remethyl Pro Vanilla is used for remethyl PN Tablet is used in the treatment of neuropathic pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Pregabalin (75mg) + Nortriptyline (10mg) + Mecobalamin (1500mcg)
Available variants: NA 200GM
Best price: ₹237 (₹1.18 per g)
MRP: ₹249
Prescription: Required
Manufacturer: R.B.PHARMACEUTICALS
Ordering notes
This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Remethyl Pro Vanilla
Remethyl Pro Vanilla contains Pregabalin (75mg) + Nortriptyline (10mg) + Mecobalamin (1500mcg). It belongs to the Gabapentinoid, Antidepressant and B-complex vitamin class of medicines.
Uses of Remethyl Pro Vanilla
Remethyl PN Tablet is used in the treatment of neuropathic pain.
Key benefits
- Works on nerve pain that ordinary painkillers do not touch
- Also used to control fits
- Effective for depression and anxiety disorders
- Also relieves nerve pain and prevents migraine
- Usually taken once a day
- Corrects a deficiency that causes tiredness and nerve symptoms
- Supports the formation of healthy red blood cells
- Generally well tolerated
How Remethyl Pro Vanilla works
Remethyl PN Tablet is a combination of three medicines: Pregabalin, Nortriptyline and Methylcobalamin/Mecobalamin. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin/Mecobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
How to take Remethyl Pro Vanilla
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Remethyl PN Tablet may be taken with or without food, but it is better to take it at a fixed time.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. It can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Remethyl Pro Vanilla
Most side effects of Remethyl Pro Vanilla are mild and settle as the body adjusts. Reported side effects include:
- Drowsiness
- Dizziness
- Swelling of the ankles and feet
- Weight gain
- Blurred vision
- Unsteadiness
- Nausea
- Dry mouth
- Drowsiness or difficulty sleeping
- Headache
- Weight change
- Reduced sexual desire
- Constipation
- Stomach upset
- Harmless bright yellow urine
- Loose motions
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Remethyl Pro Vanilla
| Pregnancy | Remethyl PN Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Remethyl PN Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Remethyl PN Tablet may cause excessive drowsiness and calmness with alcohol. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Remethyl PN Tablet should be used with caution in patients with kidney disease. Dose adjustment of Remethyl PN Tablet may be needed. Please consult your doctor. |
| Liver | Remethyl PN Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Remethyl PN Tablet may not be needed in these patients. Please consult your doctor. |
| Habit forming | Yes |
Warnings and precautions
This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry. These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.
Do not take Remethyl Pro Vanilla if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Interactions with other medicines
Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours. Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.
How to store Remethyl Pro Vanilla
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Remethyl Pro Vanilla
Take the larger part of the dose at night if drowsiness is a problem. Rise slowly from sitting or lying, especially in the first weeks. Keep your review appointment so the dose can be adjusted to the lowest that controls your pain. Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.
Manufacturer and class
- Manufacturer:
- R.B.PHARMACEUTICALS
- Therapeutic class:
- Neuropathic pain agent, Antidepressant and Vitamin supplement
- Drug class:
- Gabapentinoid, Antidepressant and B-complex vitamin
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Remethyl Pro Vanilla FAQs
What is Remethyl Pro Vanilla used for?
Remethyl Pro Vanilla is commonly used for Remethyl PN Tablet is used in the treatment of neuropathic pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Remethyl Pro Vanilla?
Remethyl Pro Vanilla contains Pregabalin (75mg) + Nortriptyline (10mg) + Mecobalamin (1500mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Remethyl Pro Vanilla?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Remethyl Pro Vanilla work?
Remethyl PN Tablet is a combination of three medicines: Pregabalin, Nortriptyline and Methylcobalamin/Mecobalamin.
Is Remethyl Pro Vanilla a prescription medicine?
Yes. Remethyl Pro Vanilla is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Remethyl Pro Vanilla?
The side effects reported most often with Remethyl Pro Vanilla are Drowsiness, Dizziness, Swelling of the ankles and feet, Weight gain, Blurred vision. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Remethyl Pro Vanilla be taken during pregnancy?
Remethyl PN Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Remethyl Pro Vanilla.
Can I drink alcohol while taking Remethyl Pro Vanilla?
Remethyl PN Tablet may cause excessive drowsiness and calmness with alcohol.
What if I miss a dose of Remethyl Pro Vanilla?
Take it as soon as you remember.
Is Remethyl Pro Vanilla habit forming?
Yes Take Remethyl Pro Vanilla only as directed and for the duration your doctor advises.
How much does Remethyl Pro Vanilla cost on PingMeDoc Pharmacy?
Remethyl Pro Vanilla starts at ₹237 (MRP ₹249) on PingMeDoc Pharmacy. Available in NA 200GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Remethyl Pro Vanilla?
Remethyl Pro Vanilla is manufactured by R.B.PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Remethyl Pro Vanilla delivered?
Remethyl Pro Vanilla is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.
Remethyl Pro Vanilla, Quick facts
- Salt
- Pregabalin (75mg) + Nortriptyline (10mg) + Mecobalamin (1500mcg)
- Best price
- ₹237 (₹1.18 per g)
- MRP
- ₹249
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- R.B.PHARMACEUTICALS
- Manufacturer
- R.B.PHARMACEUTICALS
- Therapeutic class
- Neuropathic pain agent, Antidepressant and Vitamin supplement
- Drug class
- Gabapentinoid, Antidepressant and B-complex vitamin
- Habit forming
- Yes
- Variants
- NA 200GM
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Remethyl Pro Vanilla.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.