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Prescription requiredOzone Pharmaceuticals LtdVitamins and Minerals / Nutritional supplement (Injectable)

Cynocal Plus Injection

Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: )

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Cynocal Plus Injection is used for treatment and prevention of B-complex vitamin deficiencies; supportive therapy in peripheral neuropathy/neuritis (e.g., diabetic or nutritional), neuralgia, megaloblastic anemia due to vitamin B12 deficiency, weakness and fatigue due to deficiency states (as advised by doctor).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: )
Available variants: injection 5X2ML
Best price: ₹125
MRP: ₹131
Prescription: Required
Manufacturer: OZONE PHARMACEUTICALS LTD

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Cynocal Plus Injection

Cynocal Plus Injection contains Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: ). It belongs to the Water-soluble vitamins (B-complex) class of medicines.

Uses of Cynocal Plus Injection

  • Treatment and prevention of B-complex vitamin deficiencies; supportive therapy in peripheral neuropathy/neuritis (e.g.
  • diabetic or nutritional)
  • neuralgia
  • megaloblastic anemia due to vitamin B12 deficiency
  • weakness and fatigue due to deficiency states (as advised by doctor).

Key benefits

  • Helps correct vitamin B-complex deficiency
  • Supports nerve repair and reduces neuropathic symptoms
  • Helps in megaloblastic anemia due to B12 deficiency
  • Improves energy metabolism and reduces fatigue

How Cynocal Plus Injection works

Methylcobalamin replenishes vitamin B12 needed for red blood cell formation and myelin (nerve sheath) synthesis, helping nerve repair and reducing neuropathic symptoms. Pyridoxine, nicotinamide and panthenol act as coenzymes in energy metabolism and neurotransmitter synthesis, correcting deficiency and supporting nerve and tissue function.

How to take Cynocal Plus Injection

Injection to be administered by a healthcare professional via IM or IV route as prescribed. Dose and frequency depend on indication and severity; do not self-inject. Follow your doctor’s schedule; if on other vitamin supplements, inform your clinician.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It in very large doses taken over months can itself damage nerves, causing numbness and unsteadiness. It is not a realistic risk from a moisturiser used on the skin. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Cynocal Plus Injection

Most side effects of Cynocal Plus are mild and settle as the body adjusts. Reported side effects include:

  • Injection site pain
  • redness or swelling
  • nausea
  • vomiting
  • diarrhea
  • headache
  • dizziness
  • flushing
  • rash
  • itching
  • allergic reactions (rare)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Cynocal Plus Injection

PregnancyConsult doctor
BreastfeedingGenerally considered safe while breastfeeding.
AlcoholUse with caution
DrivingNot expected to affect your ability to drive.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverNo dose change is usually needed in liver disease.
Habit formingNo

Warnings and precautions

Use only under medical supervision. Contraindicated in known hypersensitivity to any component. Caution in patients with liver disease (nicotinamide), severe renal impairment, or a history of allergy/asthma. Seek urgent help for signs of anaphylaxis (breathing difficulty, facial swelling, severe rash). Not intended to replace treatment of the underlying cause of anemia/neuropathy unless diagnosed.

Do not take Cynocal Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Levodopa (without carbidopa/benserazide) may be antagonized by pyridoxine; isoniazid, penicillamine and hydralazine can increase vitamin B6 requirement; chloramphenicol may blunt hematologic response to vitamin B12; metformin and long-term acid-suppressants may reduce B12 levels; alcohol can worsen deficiency/neuropathy.

How to store Cynocal Plus Injection

Store below 25°C. Protect from light. Do not freeze. Keep ampoules/vials in original packaging and out of reach of children.

Expert advice for Cynocal Plus Injection

A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for. Use lukewarm water, a soap substitute and short baths. Smooth it on in the direction the hair grows rather than rubbing it in hard. Keep using it when the skin looks normal — that is what prevents the next flare.

Manufacturer and class

Manufacturer:
OZONE PHARMACEUTICALS LTD
Therapeutic class:
Vitamins and Minerals / Nutritional supplement (Injectable)
Drug class:
Water-soluble vitamins (B-complex)

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Cynocal Plus Injection FAQs

What is Cynocal Plus Injection used for?
Cynocal Plus Injection is commonly used for Treatment and prevention of B-complex vitamin deficiencies; supportive therapy in peripheral neuropathy/neuritis (e.g., diabetic or nutritional), neuralgia, megaloblastic anemia due to vitamin B12 deficiency, weakness and fatigue due to deficiency states (as advised by doctor). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Cynocal Plus Injection?
Cynocal Plus Injection contains Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: ). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Cynocal Plus Injection?
Injection to be administered by a healthcare professional via IM or IV route as prescribed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Cynocal Plus Injection work?
Methylcobalamin replenishes vitamin B12 needed for red blood cell formation and myelin (nerve sheath) synthesis, helping nerve repair and reducing neuropathic symptoms.
Is Cynocal Plus Injection a prescription medicine?
Yes. Cynocal Plus Injection is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Cynocal Plus Injection?
The side effects reported most often with Cynocal Plus are Injection site pain, redness or swelling, nausea, vomiting, diarrhea. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Cynocal Plus Injection be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Cynocal Plus.
Can I drink alcohol while taking Cynocal Plus Injection?
Use with caution
What if I miss a dose of Cynocal Plus Injection?
Take it as soon as you remember.
Is Cynocal Plus Injection habit forming?
No. Cynocal Plus Injection is not known to be habit forming when taken as prescribed.
How much does Cynocal Plus Injection cost on PingMeDoc Pharmacy?
Cynocal Plus Injection starts at ₹125 (MRP ₹131) on PingMeDoc Pharmacy. Available in injection 5X2ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Cynocal Plus Injection?
Cynocal Plus Injection is manufactured by OZONE PHARMACEUTICALS LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Cynocal Plus Injection delivered?
Cynocal Plus Injection is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Cynocal Plus Injection, Quick facts

Salt
Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: )
Form
injection
Best price
₹125
MRP
₹131
Prescription
Required (Rx)
Brand
OZONE PHARMACEUTICALS LTD
Manufacturer
OZONE PHARMACEUTICALS LTD
Therapeutic class
Vitamins and Minerals / Nutritional supplement (Injectable)
Drug class
Water-soluble vitamins (B-complex)
Habit forming
No
Variants
injection 5X2ML
Delivery
Standard across India

References

The information on Cynocal Plus Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert, established medical literature on B-complex injectables
  2. Indian Pharmacopoeia monographs for individual vitamins
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Cynocal Plus Injection.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.