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Ozone Pharmaceuticals Ltd - Tablet - 550mg + 13.8mg + 500mg + 0.5mg + 750mcg - 10 S
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Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: )
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Cynocal Plus Injection is used for treatment and prevention of B-complex vitamin deficiencies; supportive therapy in peripheral neuropathy/neuritis (e.g., diabetic or nutritional), neuralgia, megaloblastic anemia due to vitamin B12 deficiency, weakness and fatigue due to deficiency states (as advised by doctor).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Cynocal Plus Injection contains Methylcobalamin (Vitamin B12) injection + Pyridoxine (Vitamin B6) injection + Nicotinamide (Vitamin B3) injection + D-Panthenol (Vitamin B5) injection (strengths: ). It belongs to the Water-soluble vitamins (B-complex) class of medicines.
Methylcobalamin replenishes vitamin B12 needed for red blood cell formation and myelin (nerve sheath) synthesis, helping nerve repair and reducing neuropathic symptoms. Pyridoxine, nicotinamide and panthenol act as coenzymes in energy metabolism and neurotransmitter synthesis, correcting deficiency and supporting nerve and tissue function.
Injection to be administered by a healthcare professional via IM or IV route as prescribed. Dose and frequency depend on indication and severity; do not self-inject. Follow your doctor’s schedule; if on other vitamin supplements, inform your clinician.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It in very large doses taken over months can itself damage nerves, causing numbness and unsteadiness. It is not a realistic risk from a moisturiser used on the skin. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Cynocal Plus are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Generally considered safe while breastfeeding. |
| Alcohol | Use with caution |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | No dose change is usually needed in liver disease. |
| Habit forming | No |
Use only under medical supervision. Contraindicated in known hypersensitivity to any component. Caution in patients with liver disease (nicotinamide), severe renal impairment, or a history of allergy/asthma. Seek urgent help for signs of anaphylaxis (breathing difficulty, facial swelling, severe rash). Not intended to replace treatment of the underlying cause of anemia/neuropathy unless diagnosed.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Levodopa (without carbidopa/benserazide) may be antagonized by pyridoxine; isoniazid, penicillamine and hydralazine can increase vitamin B6 requirement; chloramphenicol may blunt hematologic response to vitamin B12; metformin and long-term acid-suppressants may reduce B12 levels; alcohol can worsen deficiency/neuropathy.
Store below 25°C. Protect from light. Do not freeze. Keep ampoules/vials in original packaging and out of reach of children.
A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for. Use lukewarm water, a soap substitute and short baths. Smooth it on in the direction the hair grows rather than rubbing it in hard. Keep using it when the skin looks normal — that is what prevents the next flare.

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The information on Cynocal Plus Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.