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Prescription requiredSystopic LabAnti-diabetic
Dapagain-M
Metformin (500mg) + Dapagliflozin (10mg)
₹114MRP ₹1205% offIn stock
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Dapagain-M is used for this medicine is used in the treatment of type 2 diabetes, heart failure and chronic kidney disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Metformin (500mg) + Dapagliflozin (10mg)
Available variants: NA 15`S
Best price: ₹114
MRP: ₹120
Prescription: Required
Manufacturer: SYSTOPIC LAB
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Dapagain-M
Dapagain-M contains Metformin (500mg) + Dapagliflozin (10mg). It belongs to the Biguanide and SGLT2 inhibitor / GLP-1 analogue class of medicines.
Uses of Dapagain-M
- Type 2 diabetes
- Heart failure
- Chronic kidney disease
Benefits of Dapagain-M
- In Type 2 diabetes
- Dapagain-M lowers the amount of sugar your liver releases and helps your body use its own insulin, so blood sugar stays in a steadier range through the day. Keeping sugar controlled over the years protects the eyes, kidneys, nerves and heart from the damage diabetes causes.
- In Heart failure
- Dapagain-M reduces the strain on a weakened heart and lowers the chance of being admitted to hospital with fluid build-up or breathlessness.
- In Chronic kidney disease
- Dapagain-M slows the decline in kidney function and reduces protein leaking into the urine, protecting the kidneys over the long term.
How Dapagain-M works
This medicine combines 2 active ingredients: Metformin and Dapagliflozin. Metformin lowers blood sugar by reducing the amount of glucose your liver releases and by helping your muscles respond better to your own insulin. It does not force your pancreas to make more insulin, which is why it rarely causes low blood sugar on its own. Dapagliflozin lowers blood sugar by making your kidneys pass surplus glucose out in the urine, and also eases the load on the heart and kidneys.
How to take Dapagain-M
Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It can cause dehydration and a fall in blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Dapagain-M
Most side effects of Dapagain-M are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Nausea
- Loose motions
- Stomach pain
- Metallic taste
- Loss of appetite
- Flatulence
- Passing urine more often
- Thirst
- Genital itching or thrush
- Urinary infection
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Dapagain-M
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyUNSAFE
- Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
- Breast feedingUNSAFE
- Not recommended while breastfeeding.
- DrivingCAUTION
- May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
- KidneyCONSULT YOUR DOCTOR
- Consult your doctor if you have kidney disease.
- LiverCONSULT YOUR DOCTOR
- Consult your doctor if you have liver disease.
Warnings and precautions
Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs.
Do not take Dapagain-M if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.
Interactions with other medicines
Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea.
How to store Dapagain-M
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Quick tips for Dapagain-M
- Take it with or just after food to reduce stomach upset.
- Keep taking it even when your sugar readings look normal.
- That is the medicine working.
- Continue your diet and physical activity; this medicine works alongside them, not instead of them.
- Take it in the morning so the extra urine does not disturb your sleep.
- Keep up your fluid intake and maintain genital hygiene.
- Tell any doctor treating you for an acute illness that you take this medicine.
Related lab tests
People taking Dapagain-M are often asked to check these from time to time. Your doctor decides which and how often.
Manufacturer and class
- Manufacturer:
- SYSTOPIC LAB
- Therapeutic class:
- Anti-diabetic
- Drug class:
- Biguanide and SGLT2 inhibitor / GLP-1 analogue
Substitutes for Dapagain-M
Medicines with the same active ingredient (Metformin (500mg) + Dapagliflozin (10mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Dapagain-M |
|---|---|---|---|
| Dapa Cad M 500 TabletSHRRISHTI HEALTHCARE PRODUCTS(I) PVT LTD | tablet · 10`S | ₹91 | 20% cheaper |
| Cipdapla M 10/500 Tablet | 1X10 | ₹98 | 14% cheaper |
| Dapacose M 10 TabletJB CHEMICALS | tablet · 10`S | ₹143 | 25% more |
| Zucapride M 500 TabletMICRO LABS | tablet · 10`S | ₹149 | 30% more |
| Oxramet S XR 1000 mg TabletSUN PHARMA | tablet · 7`S | ₹160 | 40% more |
| Dapanorm M 10 TabletALKEM LAB | tablet · 10`S | ₹162 | 42% more |
| Justoza M 10/500 TabletMANKIND (PHARMA) | tablet · 15 Tablet | ₹168 | 47% more |
| Dapanorm M 10 Forte TabletALKEM LAB | tablet · 10`S | ₹170 | 49% more |
| Dapabite M 10/500TabCorona Remedies Pvt Ltd | tablet · 10`S | ₹170 | 49% more |
| Glifoprime M 10/500PRIMUS PHARMA | 15`S | ₹187 | 64% more |
| Sugaflo-M TabletLLOYD HEALTHCARE | tablet · 15`S | ₹211 | 85% more |
| Dapalex M 10/500 mg TabletAJANTA PHARMA | tablet · 15`S | ₹241 | 112% more |
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Dapagain-M FAQs
What is Dapagain-M used for?
Dapagain-M is commonly used for type 2 diabetes, heart failure and chronic kidney disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Dapagain-M?
Type 2 diabetes: Dapagain-M lowers the amount of sugar your liver releases and helps your body use its own insulin, so blood sugar stays in a steadier range through the day. Keeping sugar controlled over the years protects the eyes, kidneys, nerves and heart from the damage diabetes causes. It is also used for heart failure, chronic kidney disease.
What is the salt in Dapagain-M?
Dapagain-M contains Metformin (500mg) + Dapagliflozin (10mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Dapagain-M?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Dapagain-M work?
This medicine combines 2 active ingredients: Metformin and Dapagliflozin.
Is Dapagain-M a prescription medicine?
Yes. Dapagain-M is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Dapagain-M?
The side effects reported most often with Dapagain-M are Nausea, Loose motions, Stomach pain, Metallic taste, Loss of appetite. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Dapagain-M be taken during pregnancy?
Dapagain-M is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Dapagain-M.
Can I drink alcohol while taking Dapagain-M?
No. Do not drink alcohol while taking Dapagain-M.
What if I miss a dose of Dapagain-M?
Take it as soon as you remember.
Is Dapagain-M habit forming?
No. Dapagain-M is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Dapagain-M?
Dapa Cad M 500 Tablet has the same active ingredient and strength and is listed from ₹91 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Dapagain-M cost on PingMeDoc Pharmacy?
Dapagain-M starts at ₹114 (MRP ₹120) on PingMeDoc Pharmacy. Available in NA 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Dapagain-M?
Dapagain-M is manufactured by SYSTOPIC LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Dapagain-M delivered?
Dapagain-M is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Dapagain-M, Quick facts
- Salt
- Metformin (500mg) + Dapagliflozin (10mg)
- Best price
- ₹114
- MRP
- ₹120
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- SYSTOPIC LAB
- Manufacturer
- SYSTOPIC LAB
- Therapeutic class
- Anti-diabetic
- Drug class
- Biguanide and SGLT2 inhibitor / GLP-1 analogue
- Habit forming
- No
- Variants
- NA 15`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Dapagain-M.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.