Diablin E 5/25 mg Tablet

Composition of Diablin E 5/25 mg Tablet

Diablin E 5/25 mg Tablet contains Empagliflozin 25 mg + Linagliptin 5 mg tablet. It belongs to the SGLT2 inhibitor + DPP-4 inhibitor combination class of medicines.

Uses of Diablin E 5/25 mg Tablet

Type 2 diabetes mellitus: to improve glycaemic control in adults when diet and exercise alone are not sufficient; can be used with other antidiabetic medicines as advised by doctor.

Key benefits

• Lowers HbA1c and fasting/post-meal glucose
• Once-daily convenient combination
• Low risk of hypoglycaemia when used without insulin/sulfonylureas
• May aid modest weight reduction and blood pressure lowering due to SGLT2 effect

How Diablin E 5/25 mg Tablet works

Empagliflozin is an SGLT2 inhibitor that lowers blood sugar by increasing urinary glucose excretion through the kidneys. Linagliptin is a DPP-4 inhibitor that increases incretin levels, enhancing insulin release and reducing glucagon secretion in a glucose-dependent manner.

How to take Diablin E 5/25 mg Tablet

Take orally as prescribed, usually once daily at the same time each day, with or without food. Swallow whole with water; do not crush/chew. Monitor blood glucose regularly and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Diablin E 5/25 mg Tablet

Most side effects of Diablin E 5/25 mg are mild and settle as the body adjusts. Reported side effects include:

• Increased urination
• genital fungal infection
• urinary tract infection
• thirst
• low blood sugar (especially with insulin/sulfonylureas)
• nasopharyngitis
• headache
• nausea

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Diablin E 5/25 mg Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Risk of dehydration/low blood pressure especially in elderly, on diuretics, or with low fluid intake; maintain hydration. Empagliflozin may increase risk of genital infections and UTIs; seek care for fever, pain/burning urination. Monitor kidney function before and during treatment; use with caution/avoid in severe renal impairment as advised by doctor. Stop and seek medical help if symptoms of pancreatitis occur (severe abdominal pain) or severe allergic reactions. Withhold before major surgery or during acute illness/fasting as SGLT2 inhibitors can rarely cause euglycaemic ketoacidosis.

Do not take Diablin E 5/25 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk),diuretics (increased dehydration/hypotension),other antidiabetics,rifampicin/carbamazepine/phenytoin/phenobarbital (may reduce linagliptin effect),strong P-gp/CYP3A4 inducers,alcohol (may increase hypoglycaemia/dehydration risk)

How to store Diablin E 5/25 mg Tablet

Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original pack and out of reach of children.

Expert advice for Diablin E 5/25 mg Tablet

Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them.

Manufacturer and class

Manufacturer:

PRIMUS PHARMA

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + DPP-4 inhibitor combination