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Prescription requiredMsn LaboratoriesAnti-diabetic
Empaone-S 25/100 mg Tablet
Sitagliptin (100mg) + Empagliflozin (25mg)
₹204MRP ₹215In stock
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Empaone-S 25/100 mg Tablet is used for this medicine is used in the treatment of type 2 diabetes, heart failure and chronic kidney disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Sitagliptin (100mg) + Empagliflozin (25mg)
Available variants: tablet 100mg + 25mg 10`S
Best price: ₹204 (₹20.40 per tablet)
MRP: ₹215
Prescription: Required
Manufacturer: MSN LABORATORIES
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Same salt, lower price
Medicines with the same active ingredient and strength as Empaone-S 25/100 mg Tablet.
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Empaone-S 25/100 mg Tablet
tablet - 100mg + 25mg - 10 S
₹204
₹20.40 per tablet
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- Empazio M XR 25/1000MG Tab
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- Empatrol-S 25/100MG Tab
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Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Empaone-S 25/100 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Empaone-S 25/100 mg Tablet
Empaone-S 25/100 mg Tablet contains Sitagliptin (100mg) + Empagliflozin (25mg). It belongs to the DPP-4 inhibitor and SGLT2 inhibitor / GLP-1 analogue class of medicines.
Uses of Empaone-S 25/100 mg Tablet
- This medicine is used in the treatment of type 2 diabetes
- heart failure and chronic kidney disease.
Key benefits
- Weight neutral
- Low risk of hypoglycaemia when used alone
- Usually taken once a day
- Protects the heart and kidneys as well as lowering sugar
- Usually causes modest weight loss
How Empaone-S 25/100 mg Tablet works
This medicine combines 2 active ingredients: Sitagliptin and Empagliflozin. Sitagliptin lowers blood sugar by protecting the natural gut hormones that tell your pancreas to release insulin after a meal, so the effect is strongest when your sugar is highest. Empagliflozin lowers blood sugar by making your kidneys pass surplus glucose out in the urine, and also eases the load on the heart and kidneys.
How to take Empaone-S 25/100 mg Tablet
Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or without food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause dehydration and a fall in blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Empaone-S 25/100 mg Tablet
Most side effects of Empaone-S 25/100 mg are mild and settle as the body adjusts. Reported side effects include:
- Headache
- Sore throat
- Blocked or runny nose
- Nausea
- Stomach pain
- Passing urine more often
- Thirst
- Genital itching or thrush
- Urinary infection
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Empaone-S 25/100 mg Tablet
| Pregnancy | Not recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant. |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | Alcohol may worsen the side effects of this medicine. Limit it. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Warnings and precautions
Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs.
Do not take Empaone-S 25/100 mg if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.
Interactions with other medicines
Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea.
How to store Empaone-S 25/100 mg Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Empaone-S 25/100 mg Tablet
It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine.
Manufacturer and class
- Manufacturer:
- MSN LABORATORIES
- Therapeutic class:
- Anti-diabetic
- Drug class:
- DPP-4 inhibitor and SGLT2 inhibitor / GLP-1 analogue
Substitutes for Empaone-S 25/100 mg Tablet
Medicines with the same active ingredient (Sitagliptin (100mg) + Empagliflozin (25mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Empaone-S 25/100 mg Tablet |
|---|---|---|---|
| Euglif-S 25/100 mg TabletDELVIN | tablet · 10`S | ₹149 | 27% cheaper |
| Empazio M XR 25/1000 mg TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹162 | 21% cheaper |
| Empatrol-S 25/100 mg TabletARISTO PHARMACEUTICALS PVT LTD | tablet · 10`S | ₹165 | 19% cheaper |
| Alsita-E 25 mg TabletALKEM LAB | tablet · 10`S | ₹165 | 19% cheaper |
| Sitanorm-E 25 mg TabletMICRO LABS | tablet · 10`S | ₹176 | 14% cheaper |
| Empashield-S 25/100 mg TabletLARENON | tablet · 10`S | ₹177 | 13% cheaper |
| Sitahenz-E 25 TabletLARENON | tablet · 10`S | ₹177 | 13% cheaper |
| Empaglyn S 25/100 mg TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹187 | 8% cheaper |
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Empaone-S 25/100 mg Tablet FAQs
What is Empaone-S 25/100 mg Tablet used for?
Empaone-S 25/100 mg Tablet is commonly used for This medicine is used in the treatment of type 2 diabetes, heart failure and chronic kidney disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Empaone-S 25/100 mg Tablet?
Empaone-S 25/100 mg Tablet contains Sitagliptin (100mg) + Empagliflozin (25mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Empaone-S 25/100 mg Tablet?
Swallow the tablet whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Empaone-S 25/100 mg Tablet work?
This medicine combines 2 active ingredients: Sitagliptin and Empagliflozin.
Is Empaone-S 25/100 mg Tablet a prescription medicine?
Yes. Empaone-S 25/100 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Empaone-S 25/100 mg Tablet?
The side effects reported most often with Empaone-S 25/100 mg are Headache, Sore throat, Blocked or runny nose, Nausea, Stomach pain. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Empaone-S 25/100 mg Tablet be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Empaone-S 25/100 mg.
Can I drink alcohol while taking Empaone-S 25/100 mg Tablet?
Alcohol may worsen the side effects of this medicine.
What if I miss a dose of Empaone-S 25/100 mg Tablet?
Take it as soon as you remember.
Is Empaone-S 25/100 mg Tablet habit forming?
No. Empaone-S 25/100 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Empaone-S 25/100 mg Tablet?
Euglif-S 25/100 mg Tablet has the same active ingredient and strength and is listed from ₹149 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Empaone-S 25/100 mg Tablet cost on PingMeDoc Pharmacy?
Empaone-S 25/100 mg Tablet starts at ₹204 (MRP ₹215) on PingMeDoc Pharmacy. Available in tablet 100mg + 25mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Empaone-S 25/100 mg Tablet?
Empaone-S 25/100 mg Tablet is manufactured by MSN LABORATORIES. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Empaone-S 25/100 mg Tablet delivered?
Empaone-S 25/100 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Empaone-S 25/100 mg Tablet, Quick facts
- Salt
- Sitagliptin (100mg) + Empagliflozin (25mg)
- Form
- tablet
- Best price
- ₹204 (₹20.40 per tablet)
- MRP
- ₹215
- Prescription
- Required (Rx)
- Brand
- MSN LABORATORIES
- Manufacturer
- MSN LABORATORIES
- Therapeutic class
- Anti-diabetic
- Drug class
- DPP-4 inhibitor and SGLT2 inhibitor / GLP-1 analogue
- Habit forming
- No
- Variants
- tablet 100mg + 25mg 10`S
- Delivery
- Standard across India
References
The information on Empaone-S 25/100 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Empaone-S 25/100 mg Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.