Lopid 300 mg Capsule

Composition of Lopid 300 mg Capsule

Lopid 300 mg Capsule contains Gemfibrozil 300 mg capsule. It belongs to the Fibrate (PPAR-alpha agonist) class of medicines.

Uses of Lopid 300 mg Capsule

Treatment of high blood triglycerides (hypertriglyceridemia) and mixed dyslipidemia; used to reduce risk of pancreatitis in very high triglycerides and as an adjunct to diet and lifestyle changes.

Key benefits

• Lowers high triglycerides
• Reduces VLDL levels
• Modestly increases HDL cholesterol
• Helps reduce pancreatitis risk in very high triglycerides

How Lopid 300 mg Capsule works

Gemfibrozil is a fibrate that activates PPAR-α, increasing lipoprotein lipase activity and fatty-acid oxidation. This lowers triglycerides and VLDL and can modestly raise HDL cholesterol.

How to take Lopid 300 mg Capsule

Take orally as directed by a doctor, typically twice daily 30 minutes before morning and evening meals. Swallow capsule whole with water; continue diet/exercise and regular lipid monitoring.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely to cause immediate harm but may increase the risk of muscle and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lopid 300 mg Capsule

Most side effects of Lopid are mild and settle as the body adjusts. Reported side effects include:

• Dyspepsia
• abdominal pain
• nausea
• diarrhea
• headache
• dizziness
• rash
• increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lopid 300 mg Capsule

Warnings and precautions

Do not use in severe liver disease, severe kidney disease, or gallbladder disease. Risk of myopathy/rhabdomyolysis is increased when combined with statins (especially simvastatin) or in renal impairment; report muscle pain/weakness. May increase risk of gallstones and pancreatitis; monitor for abdominal pain. Periodic liver function tests and lipid levels are recommended.

Do not take Lopid if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy or while breastfeeding. Not for people with active liver disease.

Interactions with other medicines

Statins (especially simvastatin; avoid), warfarin/other anticoagulants (increased bleeding risk; monitor INR), repaglinide (contraindicated—risk of severe hypoglycemia), CYP2C8 substrates (e.g., pioglitazone; may increase levels), bile acid sequestrants (separate dosing), colchicine (increased myopathy risk)

How to store Lopid 300 mg Capsule

Store below 25°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Lopid 300 mg Capsule

Continue your diet, exercise and, above all, stopping smoking — the medicine adds to these, not replaces them. Get your lipid profile repeated as your doctor advises.

Manufacturer and class

Manufacturer:

PFIZER LTD`

Therapeutic class:

Antihyperlipidemic

Drug class:

Fibrate (PPAR-alpha agonist)