Meplol T 40/50 Tablet

Composition of Meplol T 40/50 Tablet

Meplol T 40/50 Tablet contains Telmisartan 40 mg + Metoprolol succinate (extended-release) 50 mg. It belongs to the Angiotensin II receptor blocker (ARB) + Beta-1 selective beta-blocker class of medicines.

Uses of Meplol T 40/50 Tablet

• Treatment of hypertension (high blood pressure)
• especially when a single medicine is not sufficient; helps reduce risk of cardiovascular events associated with uncontrolled BP as advised by physician

Key benefits

• Lowers high blood pressure
• Improves BP control when single drug is insufficient
• Reduces heart rate and cardiac workload
• Helps protect heart and kidneys in hypertension

How Meplol T 40/50 Tablet works

Telmisartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking angiotensin II effects, lowering blood pressure. Metoprolol succinate is a cardioselective beta-blocker that slows heart rate and reduces the force of contraction, lowering blood pressure and cardiac workload.

How to take Meplol T 40/50 Tablet

Oral tablet; take exactly as prescribed, usually once daily at the same time. Can be taken with or without food; swallow whole with water (do not crush/chew if extended-release). Do not stop suddenly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. It can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Meplol T 40/50 Tablet

Most side effects of Meplol T 40/50 are mild and settle as the body adjusts. Reported side effects include:

• dizziness
• headache
• tiredness
• slow heart rate (bradycardia)
• low blood pressure
• nausea
• diarrhea
• cold extremities

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Meplol T 40/50 Tablet

Warnings and precautions

Monitor BP and pulse regularly. May cause dizziness—use caution while driving. Do not stop metoprolol abruptly (risk of angina/arrhythmia). Use with caution in asthma/COPD, diabetes (may mask hypoglycemia symptoms), heart block, bradycardia, heart failure, liver/kidney impairment, dehydration. Telmisartan can affect kidney function and potassium—monitor creatinine and potassium; avoid potassium supplements/salt substitutes unless advised. Contraindicated in pregnancy; avoid in patients with history of hypersensitivity to components.

Do not take Meplol T 40/50 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma.

Interactions with other medicines

Other antihypertensives (additive hypotension), diuretics (first-dose hypotension), NSAIDs (reduced antihypertensive effect, kidney risk), potassium supplements/potassium-sparing diuretics (hyperkalemia), lithium (toxicity), digoxin (levels may increase with telmisartan), verapamil/diltiazem/amiodarone (bradycardia/heart block), clonidine (rebound hypertension if stopped improperly), insulin/oral antidiabetics (masked hypoglycemia), CYP2D6 inhibitors like fluoxetine/paroxetine/quinidine (increase metoprolol levels)

How to store Meplol T 40/50 Tablet

Store below 25°C in a cool, dry place; protect from moisture and light; keep in original blister pack and out of reach of children.

Expert advice for Meplol T 40/50 Tablet

Blood pressure medicines work only while you take them — do not stop because you feel well. Tell your doctor at once if you become pregnant or are planning a pregnancy. Keep a home blood-pressure record if your doctor has asked for one. Take it at the same time each day and do not miss doses. Learn to check your own pulse, and report a persistently slow one.

Manufacturer and class

Manufacturer:

MYK PHARMACEUTICALS

Therapeutic class:

Antihypertensive

Drug class:

Angiotensin II receptor blocker (ARB) + Beta-1 selective beta-blocker