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Prescription requiredSun PharmaUROLOGY

Natrise 30

Tolvaptan (30mg)

₹980MRP ₹1,031In stock
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Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Natrise 30 is used for syndrome of inappropriate antidiuretic hormone secretion (SIADH) Treatment of Low levels of sodium in the blood.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Tolvaptan (30mg)
Available variants: NA 4`S
Best price: ₹980
MRP: ₹1,031
Prescription: Required
Manufacturer: SUN PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Natrise 30

Natrise 30 contains Tolvaptan (30mg). It belongs to the Water tablet class of medicines.

Uses of Natrise 30

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Treatment of Low levels of sodium in the blood

Key benefits

  • In Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a condition where the body retains too much water
  • leading to low sodium levels in the blood. This can cause symptoms such as headache
  • nausea
  • confusion
  • weakness
  • and swelling. Natrise 30 Tablet helps remove excess water from the body without significant loss of sodium
  • which helps raise sodium levels to normal. This improves symptoms
  • restores fluid balance
  • and supports overall health and daily functioning. In Treatment of Low levels of sodium in the blood Low levels of sodium may be caused due to multiple reasons such as excess of body fluids
  • heart disease
  • and kidney problems. There may be many symptoms such as nausea
  • headache confusion and the person may even need to get hospitalized. Natrise 30 Tablet helps to get rid of the excess fluids and retains sodium in the blood. This restores the normal sodium levels in our body and prevents further complications such as memory loss. Show More

How Natrise 30 works

Natrise 30 Tablet is a vasopressin antagonist. It works by blocking the effect of the hormone vasopressin in the body. This increases urine production, reduces the amount of water in the blood and raises the blood sodium level.

How to take Natrise 30

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Natrise 30 Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Natrise 30 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Natrise 30

Most side effects of Natrise are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Natrise 30

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol CAUTION
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Take it in the morning so that passing urine does not disturb your sleep. Your doctor will check your salts and kidney function with blood tests — do not skip them. Report muscle cramps, marked weakness, confusion or an irregular heartbeat; these can be signs your potassium or sodium has fallen. In hot weather or during an illness with vomiting or loose motions, tell your doctor — you may become dehydrated quickly.

Do not take Natrise if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Anti-inflammatory painkillers blunt the effect and can strain the kidneys. Lithium and digoxin levels are affected; tell your doctor if you take either. Potassium-sparing types must not be combined with potassium supplements without supervision.

How to store Natrise 30

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Natrise 30

Natrise 30 Tablet treats low sodium levels in the blood. It also improves urine flow without causing the body to lose too much sodium as you urinate. Take it at the same time everyday. Take it according to the dose and duration prescribed by your doctor. To avoid dehydration, it is best to drink something as soon as you feel thirsty, but avoid alcoholic drinks. Do not take Natrise 30 Tablet if you are unable to urinate, if you are unable to tell when you are thirsty, or if you are severely dehydrated. You will need to be in a hospital under observation any time you start or restart treatment with Natrise 30 Tablet. Inform your doctor if you notice problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, or mood changes. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Manufacturer and class

Manufacturer:
SUN PHARMA
Therapeutic class:
UROLOGY
Drug class:
Water tablet
Chemical class:
Benzamide derivative

Substitutes for Natrise 30

Medicines with the same active ingredient (Tolvaptan (30mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Natrise 30
Tolvat 30 TabletMSN LABORATORIEStablet · 4`S₹1,0527% more
Tolvat 30 mg 15S+15FreeMSN LABORATORIES30`S₹3,946303% more
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Natrise 30 FAQs

What is Natrise 30 used for?
Natrise 30 is commonly used for Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Treatment of Low levels of sodium in the blood. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Natrise 30?
Natrise 30 contains Tolvaptan (30mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Natrise 30?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Natrise 30 work?
Natrise 30 Tablet is a vasopressin antagonist.
Is Natrise 30 a prescription medicine?
Yes. Natrise 30 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Natrise 30?
The side effects reported most often with Natrise are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Natrise 30 be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Natrise.
Can I drink alcohol while taking Natrise 30?
Alcohol CAUTION
What if I miss a dose of Natrise 30?
If you miss a dose of Natrise 30 Tablet, take it as soon as possible.
Is Natrise 30 habit forming?
No. Natrise 30 is not known to be habit forming when taken as prescribed.
How much does Natrise 30 cost on PingMeDoc Pharmacy?
Natrise 30 starts at ₹980 (MRP ₹1,031) on PingMeDoc Pharmacy. Available in NA 4`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Natrise 30?
Natrise 30 is manufactured by SUN PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Natrise 30 delivered?
Natrise 30 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Natrise 30, Quick facts

Salt
Tolvaptan (30mg)
Best price
₹980
MRP
₹1,031
Prescription
Required (Rx)
Brand
SUN PHARMA
Manufacturer
SUN PHARMA
Therapeutic class
UROLOGY
Drug class
Water tablet
Chemical class
Benzamide derivative
Action class
Vasopressin Antagonists
Habit forming
No
Variants
NA 4`S
Delivery
Standard across India

References

The information on Natrise 30 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Natrise 30.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.