
8X Cream
Cipla Limited - Cream - 1%W/W - 30 G
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Calcium (250mg) + Vitamin D3 (400IU) + Risedronate (35mg)
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Risofos 75 is used for risofos 35mg/250mg/400IU Kit is used in the treatment of osteoporosis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Risofos 75 contains Calcium (250mg) + Vitamin D3 (400IU) + Risedronate (35mg). It belongs to the Vitamin D / calcium supplement and Hormone preparation class of medicines.
Risofos 35mg/250mg/400IU Kit is used in the treatment of osteoporosis.
Risofos 35mg/250mg/400IU Kit is a combination of two medicines: Risedronate, Calcium and Vitamin D3 which treat osteoporosis. Risedronate is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bone and minimizes the risk of fractures. Calcium helps build and maintain bones, while Vitamin D3 helps your body effectively absorb Calcium. Vitamin D3 additionally supports the muscles needed to avoid falls.
Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Risofos 35mg/250mg/400IU Kit is to be taken empty stomach.<br/>Take it in the morning right after getting up from the bed. Do not drink or eat anything atleast for 30 minutes after taking this medicine.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can raise blood calcium dangerously, causing thirst, frequent urination, vomiting, confusion and kidney damage. It may cause nausea, vomiting and withdrawal bleeding. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Risofos are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Risofos 35mg/250mg/400IU Kit may be unsafe to use during pregnancy.<br/>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Risofos 35mg/250mg/400IU Kit is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | Interaction with alcohol is unknown. Please consult your doctor. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Risofos 35mg/250mg/400IU Kit is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Risofos 35mg/250mg/400IU Kit may not be needed in these patients. Please consult your doctor. |
| Liver | Risofos 35mg/250mg/400IU Kit is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Risofos 35mg/250mg/400IU Kit may not be needed in these patients. Please consult your doctor. |
| Habit forming | No |
Do not take more than your doctor has advised. Vitamin D builds up in the body and too much raises blood calcium, causing thirst, frequent urination, nausea and confusion. High-dose weekly or monthly sachets are prescription strengths — do not repeat one because you missed a week. Tell your doctor if you have had kidney stones or have kidney disease. Take a hormonal medicine at the same time every day; the effect depends on a steady level. Seek urgent care for sudden chest pain, breathlessness, severe headache, weakness on one side, or pain and swelling in a calf — hormone preparations can raise the risk of clots. Tell your doctor if you smoke, have migraine with aura, high blood pressure, or a family history of clots or breast cancer, before starting. Report any unusual or heavy vaginal bleeding to your doctor.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a high blood calcium level, or with certain kidney stones. Not for people with a history of blood clots, certain hormone-sensitive cancers, or active liver disease. Several are contraindicated in pregnancy.
Calcium reduces the absorption of thyroid tablets, several antibiotics and iron — separate them by a few hours. Water tablets of the thiazide group raise calcium further when combined. Rifampicin, several anti-epileptics and St John's wort make hormonal contraception unreliable. Tell your doctor about every medicine, supplement and herbal product you take.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>Take it first thing in the morning on an empty stomach. Do not lie down after taking the medicine.</div></li> <li><div>Wait at least 1 hour before taking any other medication or eating or drinking anything.</div></li> <li><div>Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Risofos 35mg/250mg/400IU Kit.</div></li> <li><div>Inform your doctor if you experience pain in jaw. This problem may be seen after dental work.</div></li> <li>Your doctor will monitor your response to Risofos 35mg/250mg/400IU Kit by testing your bone mineral density (BMD). This is usually done every 1-3 years.</li></ul></div></div></div></div></div></div>

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.