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Unison Pharmaceuticals - Tablet - 10 S
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Dapagliflozin (10mg) + Metformin (500mg) + Sitagliptin (100mg)
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Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Sitason Dm 500 Tablet is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Sitason Dm 500 Tablet contains Dapagliflozin (10mg) + Metformin (500mg) + Sitagliptin (100mg). It belongs to the SGLT2 inhibitor / GLP-1 analogue, Biguanide and DPP-4 inhibitor class of medicines.
Treatment of Type 2 diabetes mellitus
Sitason-M 50/500 Tablet is a combination of two medicines: sitagliptin and metformin. Sitagliptin helps your pancreas produce more insulin, facilitates effective use of insulin by the body, and reduces excess sugar that your liver makes. Metformin is a biguanide that lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitason-M 50/500 Tablet should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Sitason-M 50/500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Sitason Dm are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take Sitason-M 50/500 Tablet with food to lower your chance of having an upset stomach. Take it in addition to regular exercise and a healthy diet to lower blood sugar levels. The chances of weight gain and low blood sugar are lower than with other diabetes medicines. Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Sitason-M 50/500 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Medicines with the same active ingredient (Dapagliflozin (10mg) + Metformin (500mg) + Sitagliptin (100mg)). Ask your doctor or pharmacist before switching brands.
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|---|---|---|---|
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| Dapahenz Sm 500 TabletLARENON | tablet · 10`S | ₹245 | 139% more |

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The information on Sitason Dm 500 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.