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Prescription requiredGlenmark PharmaceuticalsAntidiabetic
Zita Pio Met 1000 Tablet
Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 1000 mg (as metformin hydrochloride) tablet
₹170MRP ₹1795% offIn stock
Order on WhatsAppDelivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.
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Zita Pio Met 1000 Tablet is used for type 2 diabetes mellitus: to improve glycaemic control in adults when diet and exercise plus other antidiabetic medicines are not adequate.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 1000 mg (as metformin hydrochloride) tablet
Available variants: tablet 100mg + 15mg + 1000mg 10`S
Best price: ₹170 (₹16.97 per tablet)
MRP: ₹179
Prescription: Required
Manufacturer: GLENMARK PHARMACEUTICALS
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Same salt, lower price
Medicines with the same active ingredient and strength as Zita Pio Met 1000 Tablet.
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Zita Pio Met 1000 Tablet
tablet - 100mg + 15mg + 1000mg - 10 S
₹170
₹16.97 per tablet
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ARISTO PHARMACEUTICALS PVT LTD · tablet - 1000mg + 15mg + 100mg - 15 S · Rx
Save 29%₹180
₹11.97 per tablet
- Sitaglo Mp 1000MG Tab
ARISTO PHARMACEUTICALS PVT LTD · tablet - 1000 mg - 10 S · Rx
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₹15.28 per tablet
Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Zita Pio Met 1000 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Zita Pio Met 1000 Tablet
Zita Pio Met 1000 Tablet contains Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 1000 mg (as metformin hydrochloride) tablet. It belongs to the DPP-4 inhibitor + Thiazolidinedione (TZD) + Biguanide class of medicines.
Uses of Zita Pio Met 1000 Tablet
Type 2 diabetes mellitus: to improve glycaemic control in adults when diet and exercise plus other antidiabetic medicines are not adequate
Key benefits
- Lowers fasting and post-meal blood glucose
- Improves insulin sensitivity
- Reduces hepatic glucose output
- Helps achieve better HbA1c control in type 2 diabetes
How Zita Pio Met 1000 Tablet works
Sitagliptin (DPP-4 inhibitor) increases incretin hormones, which raise insulin release and reduce glucagon after meals. Metformin reduces liver glucose production and improves insulin sensitivity. Pioglitazone (TZD) increases insulin sensitivity in muscle and adipose tissue, improving glucose uptake.
How to take Zita Pio Met 1000 Tablet
Oral tablet; take exactly as prescribed. Usually taken with meals to reduce stomach upset; swallow whole with water. Monitor blood glucose regularly; do not stop abruptly without medical advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It may cause low blood sugar and marked stomach upset. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Zita Pio Met 1000 Tablet
Most side effects of Zita Pio Met are mild and settle as the body adjusts. Reported side effects include:
- Nausea
- diarrhoea
- abdominal discomfort
- headache
- dizziness
- peripheral oedema (swelling)
- weight gain
- upper respiratory tract infection
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Zita Pio Met 1000 Tablet
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Warnings and precautions
For type 2 diabetes only; not for type 1 diabetes or diabetic ketoacidosis. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, severe infection, alcoholism, or hypoxia; assess renal function before and during treatment and stop temporarily before iodinated contrast/surgery as advised. Pioglitazone can cause fluid retention and may worsen heart failure; monitor for rapid weight gain/shortness of breath. Risk of hypoglycaemia increases when used with insulin or sulfonylureas. Sitagliptin has been associated with pancreatitis and severe joint pain; seek care for severe abdominal pain. Use caution in liver disease; monitor liver enzymes. Periodic vitamin B12 monitoring may be needed with long-term metformin.
Do not take Zita Pio Met if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Interactions with other medicines
Alcohol (increases lactic acidosis risk with metformin), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate/acetazolamide), cationic drugs eliminated by renal secretion (e.g., cimetidine), insulin and sulfonylureas (increased hypoglycaemia risk), corticosteroids/thyroid hormones/diuretics (may raise glucose), rifampicin (may reduce pioglitazone effect), gemfibrozil (may increase pioglitazone levels)
How to store Zita Pio Met 1000 Tablet
Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.
Expert advice for Zita Pio Met 1000 Tablet
It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with the first mouthful of your meal so it can act on that meal. Expect some wind in the first weeks; it usually settles. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.
Manufacturer and class
- Manufacturer:
- GLENMARK PHARMACEUTICALS
- Therapeutic class:
- Antidiabetic
- Drug class:
- DPP-4 inhibitor + Thiazolidinedione (TZD) + Biguanide
Substitutes for Zita Pio Met 1000 Tablet
Medicines with the same active ingredient (Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 1000 mg (as metformin hydrochloride) tablet). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Zita Pio Met 1000 Tablet |
|---|---|---|---|
| Sitaglo Mp 1000 mg TabletARISTO PHARMACEUTICALS PVT LTD | tablet · 10`S | ₹153 | 10% cheaper |
| Sitaglo M Forte 50/1000 TabletARISTO PHARMACEUTICALS PVT LTD | tablet · 15`S | ₹180 | 6% more |
| Alsita Mp 1000 TabletALKEM LAB | tablet · 10`S | ₹218 | 29% more |
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Zita Pio Met 1000 Tablet FAQs
What is Zita Pio Met 1000 Tablet used for?
Zita Pio Met 1000 Tablet is commonly used for Type 2 diabetes mellitus: to improve glycaemic control in adults when diet and exercise plus other antidiabetic medicines are not adequate. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zita Pio Met 1000 Tablet?
Zita Pio Met 1000 Tablet contains Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 1000 mg (as metformin hydrochloride) tablet. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zita Pio Met 1000 Tablet?
Oral tablet; take exactly as prescribed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zita Pio Met 1000 Tablet work?
Sitagliptin (DPP-4 inhibitor) increases incretin hormones, which raise insulin release and reduce glucagon after meals.
Is Zita Pio Met 1000 Tablet a prescription medicine?
Yes. Zita Pio Met 1000 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zita Pio Met 1000 Tablet?
The side effects reported most often with Zita Pio Met are Nausea, diarrhoea, abdominal discomfort, headache, dizziness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zita Pio Met 1000 Tablet be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zita Pio Met.
Can I drink alcohol while taking Zita Pio Met 1000 Tablet?
Avoid
What if I miss a dose of Zita Pio Met 1000 Tablet?
Take it as soon as you remember.
Is Zita Pio Met 1000 Tablet habit forming?
No. Zita Pio Met 1000 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Zita Pio Met 1000 Tablet?
Sitaglo Mp 1000 mg Tablet has the same active ingredient and strength and is listed from ₹153 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Zita Pio Met 1000 Tablet cost on PingMeDoc Pharmacy?
Zita Pio Met 1000 Tablet starts at ₹170 (MRP ₹179) on PingMeDoc Pharmacy. Available in tablet 100mg + 15mg + 1000mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zita Pio Met 1000 Tablet?
Zita Pio Met 1000 Tablet is manufactured by GLENMARK PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zita Pio Met 1000 Tablet delivered?
Zita Pio Met 1000 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Zita Pio Met 1000 Tablet, Quick facts
- Salt
- Sitagliptin 100 mg + Pioglitazone 15 mg + Metformin 1000 mg (as metformin hydrochloride) tablet
- Form
- tablet
- Best price
- ₹170 (₹16.97 per tablet)
- MRP
- ₹179
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- GLENMARK PHARMACEUTICALS
- Manufacturer
- GLENMARK PHARMACEUTICALS
- Therapeutic class
- Antidiabetic
- Drug class
- DPP-4 inhibitor + Thiazolidinedione (TZD) + Biguanide
- Habit forming
- No
- Variants
- tablet 100mg + 15mg + 1000mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling
- CDSCO/drug safety communications, established medical literature (DPP-4 inhibitors, metformin, pioglitazone)
- Indian Pharmacopoeia (general standards)
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Zita Pio Met 1000 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.