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Prescription requiredBeat PharmaAnti-diabetic

Glimsafe 1Mf Plus Tablet

Glimepiride (1mg) + Metformin (500mg)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

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  • Zoryl-1₹59View
  • Metsmall 500 mg Tablet₹62View

Glimsafe 1Mf Plus Tablet is used for glimsafe MF 2mg/500mg Tablet is used in the treatment of type 2 diabetes.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Glimepiride (1mg) + Metformin (500mg)
Available variants: tablet 1mg + 500mg 10`S
Best price: ₹89 (₹8.91 per tablet)
MRP: ₹94
Prescription: Required
Manufacturer: BEAT PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Glimsafe 1Mf Plus Tablet.

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Glimsafe 1Mf Plus Tablet

tablet - 1mg + 500mg - 10 S

₹89

₹8.91 per tablet

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Glimsafe 1Mf Plus Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Glimsafe 1Mf Plus Tablet

Glimsafe 1Mf Plus Tablet contains Glimepiride (1mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.

Uses of Glimsafe 1Mf Plus Tablet

Glimsafe MF 2mg/500mg Tablet is used in the treatment of type 2 diabetes.

Key benefits

  • Lowers blood sugar quickly
  • Long-established and inexpensive
  • First-choice medicine for type 2 diabetes
  • Does not usually cause weight gain
  • Low risk of hypoglycaemia when used alone

How Glimsafe 1Mf Plus Tablet works

Glimsafe MF 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

How to take Glimsafe 1Mf Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glimsafe MF 2mg/500mg Tablet is to be taken with food.<br>Glimsafe MF 2mg/500mg Tablet may cause stomach upset if taken empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glimsafe 1Mf Plus Tablet

Most side effects of Glimsafe 1Mf Plus are mild and settle as the body adjusts. Reported side effects include:

  • Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glimsafe 1Mf Plus Tablet

PregnancyGlimsafe MF 2mg/500mg Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingGlimsafe MF 2mg/500mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholTaking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyGlimsafe MF 2mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glimsafe MF 2mg/500mg Tablet may be needed. Please consult your doctor.<br>Use of Glimsafe MF 2mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
LiverGlimsafe MF 2mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Glimsafe MF 2mg/500mg Tablet may be needed. Please consult your doctor.<br>Glimsafe MF 2mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Habit formingNo

Warnings and precautions

If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Glimsafe 1Mf Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Glimsafe 1Mf Plus Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Glimsafe 1Mf Plus Tablet

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glimsafe-1MF Tablet PR.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li>Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.</li> <li>It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. </li> <li>Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glimsafe-1MF Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.</li> <li>Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
BEAT PHARMA
Therapeutic class:
Anti-diabetic
Drug class:
Sulfonylurea and Biguanide

Substitutes for Glimsafe 1Mf Plus Tablet

Medicines with the same active ingredient (Glimepiride (1mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Glimsafe 1Mf Plus Tablet
Glimison M1 TabletUNISON PHARMACEUTICALStablet · 15`S₹3857% cheaper
Zoryl-1Intas Pharmaceuticals Ltd15`S₹5934% cheaper
Metsmall 500 mg TabletDr Reddys Laboratories Ltdtablet · 30`S₹6231% cheaper
Icarmet G2ICARUS HEALTHCARE10`S₹6725% cheaper
Yogamet gm 1 TabletHIGLANCEtablet · 10`S₹7021% cheaper
Gride M TabletEAST WEST PHARMAtablet · 10`S₹7515% cheaper
Glidot-M1 TabletMEDI DOT IN PHARMAtablet · 15`S₹873% cheaper
Zetaglim-M1 TabletELINOR PHARMACEUTICALS PVT LTDtablet · 15`S₹872% cheaper
Glimilan GM1 TabletCLEVELAND PHARMACEUTICALStablet · 10`S₹872% cheaper
Glisimet M1 TabletEYSYS PHARMAtablet · 14`S₹912% more
Glimibrit M 1 TabletElbrit LIfe Sciencestablet · 15 Tablet₹10114% more
Glimibrit M1 ForteElbrit LIfe Sciences15`S₹11023% more
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Glimsafe 1Mf Plus Tablet FAQs

What is Glimsafe 1Mf Plus Tablet used for?
Glimsafe 1Mf Plus Tablet is commonly used for Glimsafe MF 2mg/500mg Tablet is used in the treatment of type 2 diabetes. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Glimsafe 1Mf Plus Tablet?
Glimsafe 1Mf Plus Tablet contains Glimepiride (1mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Glimsafe 1Mf Plus Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Glimsafe 1Mf Plus Tablet work?
Glimsafe MF 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin.
Is Glimsafe 1Mf Plus Tablet a prescription medicine?
Yes. Glimsafe 1Mf Plus Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Glimsafe 1Mf Plus Tablet?
The side effects reported most often with Glimsafe 1Mf Plus are Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Glimsafe 1Mf Plus Tablet be taken during pregnancy?
Glimsafe MF 2mg/500mg Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Glimsafe 1Mf Plus.
Can I drink alcohol while taking Glimsafe 1Mf Plus Tablet?
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
What if I miss a dose of Glimsafe 1Mf Plus Tablet?
Take it as soon as you remember.
Is Glimsafe 1Mf Plus Tablet habit forming?
No. Glimsafe 1Mf Plus Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Glimsafe 1Mf Plus Tablet?
Glimison M1 Tablet has the same active ingredient and strength and is listed from ₹38 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Glimsafe 1Mf Plus Tablet cost on PingMeDoc Pharmacy?
Glimsafe 1Mf Plus Tablet starts at ₹89 (MRP ₹94) on PingMeDoc Pharmacy. Available in tablet 1mg + 500mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Glimsafe 1Mf Plus Tablet?
Glimsafe 1Mf Plus Tablet is manufactured by BEAT PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Glimsafe 1Mf Plus Tablet delivered?
Glimsafe 1Mf Plus Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Glimsafe 1Mf Plus Tablet, Quick facts

Salt
Glimepiride (1mg) + Metformin (500mg)
Form
tablet
Best price
₹89 (₹8.91 per tablet)
MRP
₹94
Prescription
Required (Rx)
Schedule
Schedule H
Brand
BEAT PHARMA
Manufacturer
BEAT PHARMA
Therapeutic class
Anti-diabetic
Drug class
Sulfonylurea and Biguanide
Habit forming
No
Variants
tablet 1mg + 500mg 10`S
Delivery
Standard across India

References

The information on Glimsafe 1Mf Plus Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Glimsafe 1Mf Plus Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.