
Acuclav 375
Macleods Pharmaceuticals Pvt Ltd - 10 S
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Dapagliflozin (5mg) + Sitagliptin (50mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Macsita D 50/5 mg Tablet is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Macsita D 50/5 mg Tablet.
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Macsita D 50/5 mg Tablet
tablet - 5mg + 50mg - 10 S
₹126
₹12.65 per tablet
D EARTH PHARMACEUTICALS · tablet - 5mg + 50mg - 10 S · Rx
₹90
₹9.03 per tablet
Zuventus Healthcare Ltd · tablet - 5mg + 50mg - 10 S · Rx
₹97
₹9.69 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Macsita D 50/5 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Macsita D 50/5 mg Tablet contains Dapagliflozin (5mg) + Sitagliptin (50mg). It belongs to the SGLT2 inhibitor / GLP-1 analogue and DPP-4 inhibitor class of medicines.
Treatment of Type 2 diabetes mellitus
Macsita-D 50/5 Tablet is a combination of two antidiabetic medications. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Sitagliptin reduces the amount of glucose produced by the liver by raising insulin levels and decreasing the levels of glucagon (the hormone that increases blood glucose levels).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macsita-D 50/5 Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Macsita-D 50/5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause dehydration and a fall in blood pressure. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Macsita D 50/5 mg are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CAUTION |
| Kidney | Kidney UNSAFE |
| Liver | Liver CAUTION |
| Habit forming | No |
Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.
Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Macsita-D 50/5 Tablet is used alone or together with other diabetes medicines to control blood sugar and avoid long-term complications. It also reduces the risk of heart attack, heart failure, or other cardiovascular events. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) along with Macsita-D 50/5 Tablet. It may cause your body to lose too much fluid (dehydration), or you may urinate more often. Drink plenty of water and stay hydrated. It can cause genital fungal and/or urinary tract infections (UTIs) in both females and males, so practice good hygiene. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool, pale skin, tremor, and anxiety. Inform your doctor immediately if you experience constant dizziness, joint pain, cold-like symptoms, or unexplained nausea/vomiting. Monitor your blood sugar regularly while taking this medicine.
Medicines with the same active ingredient (Dapagliflozin (5mg) + Sitagliptin (50mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Macsita D 50/5 mg Tablet |
|---|---|---|---|
| Dapaearth-S 5/50 mg TabletD EARTH PHARMACEUTICALS | tablet · 10`S | ₹90 | 29% cheaper |
| Zensita -D 50/5 mg TabletZuventus Healthcare Ltd | tablet · 10`S | ₹97 | 23% cheaper |
| Sitadapa 50/5 mg TabletMacleods Pharmaceuticals Pvt Ltd | tablet · 10`S | ₹139 | 10% more |
| Dapacose 5 mg TabletJB CHEMICALS | tablet · 10`S | ₹143 | 13% more |
| Sitara D 50/5 TabletIntas Pharmaceuticals Ltd | tablet · 10S | ₹149 | 17% more |
| Stalix D 5+50 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹164 | 29% more |
| Dapaneu-S 5/50 TabletNEUCURE HEALTHCARE PVT LTD | tablet · 15`S | ₹220 | 74% more |

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The information on Macsita D 50/5 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.