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Prescription requiredIpca Laboratories Ltd`Antihypertensive / Heart failure therapy

Sacumada 100 Tablet

Sacubitril (49mg) + Valsartan (51mg)

Sacumada 100 Tablet is used for treatment of chronic heart failure (particularly heart failure with reduced ejection fraction, HFrEF) to reduce the risk of cardiovascular death and hospitalization.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹407₹29.06 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Sacubitril (49mg) + Valsartan (51mg)
Available variants: tablet tablet 14`S
Best price: ₹407 (₹29.06 per tablet)
Prescription: Required
Manufacturer: IPCA LABORATORIES LTD`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

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Sacumada 100 Tablet

tablet - 14 S

₹407

₹29.06 per tablet

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Sacumada 100 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Sacumada 100 Tablet

Sacumada 100 Tablet contains Sacubitril (49mg) + Valsartan (51mg). It belongs to the ARNI (Angiotensin Receptor Neprilysin Inhibitor) class of medicines.

Uses of Sacumada 100 Tablet

  • Treatment of chronic heart failure (particularly heart failure with reduced ejection fraction
  • HFrEF) to reduce the risk of cardiovascular death and hospitalization.

Key benefits

  • Reduces risk of hospitalization in chronic heart failure
  • Reduces cardiovascular death risk in HFrEF
  • Improves symptoms like breathlessness and fatigue
  • Helps reduce fluid overload and cardiac workload

How Sacumada 100 Tablet works

Sacubitril inhibits neprilysin, increasing levels of beneficial natriuretic peptides leading to vasodilation and reduced fluid overload. Valsartan blocks angiotensin II (AT1) receptors, reducing vasoconstriction and aldosterone effects. Together they lower cardiac workload and improve heart failure outcomes.

How to take Sacumada 100 Tablet

Take as prescribed by the doctor, usually twice daily, with or without food. Swallow the tablet whole with water; do not crush or chew. Dose is titrated based on blood pressure, kidney function and tolerance; do not stop abruptly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sacumada 100 Tablet

Most side effects of Sacumada are mild and settle as the body adjusts. Reported side effects include:

  • Low blood pressure (hypotension)
  • dizziness
  • raised potassium (hyperkalaemia)
  • kidney function changes
  • increased creatinine
  • cough
  • diarrhoea
  • angioedema (rare but serious)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sacumada 100 Tablet

PregnancyNot recommended (contraindicated in pregnancy); consult doctor immediately if pregnant or planning pregnancy.
BreastfeedingHefcard 49mg/51mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AlcoholUse with caution; alcohol may increase dizziness and blood pressure lowering effects.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyAlsectan 49mg/51mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Alsectan 49mg/51mg Tablet may be needed. Please consult your doctor.Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
LiverSacumada 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Sacumada 100 Tablet may be needed. Please consult your doctor.No dose adjustment is recommended in patients with mild to moderate liver disease.
Habit formingNo

Warnings and precautions

Contraindicated with a history of angioedema related to ACE inhibitors/ARBs. Do not use together with an ACE inhibitor; maintain a 36-hour washout when switching from an ACE inhibitor due to angioedema risk. Use with caution in low blood pressure, dehydration, kidney impairment, hyperkalaemia, severe liver disease; monitor BP, serum potassium and renal function. Avoid in pregnancy; can harm the unborn baby. Seek emergency care for facial/lip/tongue swelling or breathing difficulty.

Do not take Sacumada if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines.

Interactions with other medicines

ACE inhibitors (contraindicated; 36-hour washout required),aliskiren (avoid in diabetes; caution in renal impairment),potassium supplements/potassium-sparing diuretics (e.g., spironolactone, eplerenone, amiloride) and salt substitutes (hyperkalaemia),NSAIDs (may worsen kidney function),lithium (increased lithium levels/toxicity),other antihypertensives/diuretics (additive hypotension)

How to store Sacumada 100 Tablet

Store below 30°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Expert advice for Sacumada 100 Tablet

Blood pressure medicines work only while you take them — do not stop because you feel well. Tell your doctor at once if you become pregnant or are planning a pregnancy. Keep a home blood-pressure record if your doctor has asked for one.

Manufacturer and class

Manufacturer:
IPCA LABORATORIES LTD`
Therapeutic class:
Antihypertensive / Heart failure therapy
Drug class:
ARNI (Angiotensin Receptor Neprilysin Inhibitor)

Substitutes for Sacumada 100 Tablet

Medicines with the same active ingredient (Sacubitril (49mg) + Valsartan (51mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Sacumada 100 Tablet
Arnx 50 mg TabletZYDUS HEALTHCARE PHARMAtablet · 10`S₹22645% cheaper
Arnx 100 mg TabletZYDUS HEALTHCARE PHARMAtablet · 10`S₹25737% cheaper
Saculysin 50 mg TabletLARENONtablet · 14`S₹27433% cheaper
Sacutan 100 TabletMSN LABORATORIEStablet · 14`S₹33917% cheaper
Arnicor 100 TabletCIPLA LIMITEDtablet · 10`S₹34016% cheaper
Sacustart-100 mg TabletSANZ PHARMACEUTICALStablet · 14`S₹3924% cheaper
Arnipin 100 TabletLUPIN LABtablet · 10`S₹3963% cheaper
Azmarda 100 mg TabletJB CHEMICALStablet · 14`S₹939131% more
Vymada 100 mg TabletNovartis India Ltdtablet · 2X14`S₹1,889364% more
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Sacumada 100 Tablet FAQs

What is Sacumada 100 Tablet used for?
Sacumada 100 Tablet is commonly used for Treatment of chronic heart failure (particularly heart failure with reduced ejection fraction, HFrEF) to reduce the risk of cardiovascular death and hospitalization. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Sacumada 100 Tablet?
Sacumada 100 Tablet contains Sacubitril (49mg) + Valsartan (51mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Sacumada 100 Tablet?
Take as prescribed by the doctor, usually twice daily, with or without food. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Sacumada 100 Tablet work?
Sacubitril inhibits neprilysin, increasing levels of beneficial natriuretic peptides leading to vasodilation and reduced fluid overload.
Is Sacumada 100 Tablet a prescription medicine?
Yes. Sacumada 100 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Sacumada 100 Tablet?
The side effects reported most often with Sacumada are Low blood pressure (hypotension), dizziness, raised potassium (hyperkalaemia), kidney function changes, increased creatinine. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Sacumada 100 Tablet be taken during pregnancy?
Not recommended (contraindicated in pregnancy); consult doctor immediately if pregnant or planning pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Sacumada.
Can I drink alcohol while taking Sacumada 100 Tablet?
Use with caution; alcohol may increase dizziness and blood pressure lowering effects.
What if I miss a dose of Sacumada 100 Tablet?
Take it as soon as you remember.
Is Sacumada 100 Tablet habit forming?
No. Sacumada 100 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Sacumada 100 Tablet?
Arnx 50 mg Tablet has the same active ingredient and strength and is listed from ₹226 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Sacumada 100 Tablet cost on PingMeDoc Pharmacy?
Sacumada 100 Tablet starts at ₹407 on PingMeDoc Pharmacy. Available in tablet tablet 14`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Sacumada 100 Tablet?
Sacumada 100 Tablet is manufactured by IPCA LABORATORIES LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Sacumada 100 Tablet delivered?
Sacumada 100 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Sacumada 100 Tablet, Quick facts

Salt
Sacubitril (49mg) + Valsartan (51mg)
Form
tablet
Best price
₹407 (₹29.06 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
IPCA LABORATORIES LTD`
Manufacturer
IPCA LABORATORIES LTD`
Therapeutic class
Antihypertensive / Heart failure therapy
Drug class
ARNI (Angiotensin Receptor Neprilysin Inhibitor)
Habit forming
No
Variants
tablet tablet 14`S
Delivery
Standard across India

References

The information on Sacumada 100 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/prescribing information,Established medical literature (heart failure guidelines),Class monographs for sacubitril/valsartan
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Sacumada 100 Tablet.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.