
Aceclo 100MG
Aristo Pharmaceuticals Pvt Ltd - 100 mg - 10 S
Prescription required
Amlodipine (5mg) + Metoprolol Succinate (25mg)
Amlosafe Mt 25 is used for treatment of hypertension (high blood pressure); management of chronic stable angina (chest pain) and reduction of blood pressure in patients requiring combination therapy.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Amlosafe Mt 25 contains Amlodipine (5mg) + Metoprolol Succinate (25mg). It belongs to the Calcium channel blocker + Beta-1 selective beta-blocker (extended-release) class of medicines.
Treatment of hypertension (high blood pressure); management of chronic stable angina (chest pain) and reduction of blood pressure in patients requiring combination therapy
Amlodipine is a calcium channel blocker that relaxes blood vessels, improving blood flow and lowering blood pressure. Metoprolol succinate is a cardioselective beta-blocker that slows heart rate and reduces the force of contraction, lowering blood pressure and decreasing cardiac workload.
Take by mouth as directed by the doctor, usually once daily at the same time each day. Swallow the tablet whole with water; do not crush or chew (extended-release component). Can be taken with or without food; avoid stopping suddenly without medical advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Amlosafe MT 25 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Amlosafe Mt than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Amlosafe Mt are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding CAUTION |
| Alcohol | Use with caution |
| Driving | Driving CAUTION |
| Kidney | Kidney CONSULT YOUR DOCTOR |
| Liver | Liver UNSAFE |
| Habit forming | No |
Do not stop metoprolol abruptly (risk of worsening angina/heart issues). Use with caution in asthma/COPD, diabetes (may mask hypoglycemia), heart block, severe bradycardia, heart failure, and liver disease. Monitor blood pressure and pulse regularly; may cause dizziness—use caution while driving. Seek urgent care for fainting, very slow pulse, severe breathlessness, or swelling suggestive of heart failure.
Other antihypertensives (additive BP lowering),verapamil/diltiazem/amiodarone/digoxin (risk of bradycardia/heart block),clonidine (withdrawal interactions),CYP3A4 inhibitors like clarithromycin/itraconazole (increase amlodipine),rifampicin (may reduce amlodipine),NSAIDs (may reduce antihypertensive effect),insulin/oral antidiabetics (beta-blocker may mask hypoglycemia),MAO inhibitors (caution)
Store below 25°C in a cool, dry place protected from light and moisture. Keep in original strip and out of reach of children.
It may cause dizziness. Get up slowly when rising from a sitting or lying position. Do not stop taking the medication suddenly without talking to your doctor as it can cause sudden increase in your blood pressure. Let your doctor know if you are pregnant or planning for pregnancy.
Medicines with the same active ingredient (Amlodipine (5mg) + Metoprolol Succinate (25mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Amlosafe Mt 25 |
|---|---|---|---|
| Saanbeta XL 25 TabletSAAN LAB LLP | tablet · 10`S | ₹48 | 38% cheaper |
| Saanbeta XL Am 25 TabletSAAN LAB LLP | tablet · 10`S | ₹53 | 32% cheaper |
| Prolomet AM 25 TabletSUN PHARMA | tablet · 10 Tablet | ₹131 | 71% more |
| Met Stamlo Capsule | capsule · 10 Capsules | ₹162 | 110% more |

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Prescription required

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The information on Amlosafe Mt 25 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.