Complamina Retard 500 mg Tablet

Composition of Complamina Retard 500 mg Tablet

Complamina Retard 500 mg Tablet contains Pentoxifylline 500 mg (sustained/extended release) tablet. It belongs to the Methylxanthine derivative (hemorheologic agent; non-selective phosphodiesterase inhibitor) class of medicines.

Uses of Complamina Retard 500 mg Tablet

Peripheral arterial occlusive disease (intermittent claudication) due to poor blood circulation; adjunct in peripheral vascular disease to improve walking distance and reduce leg pain/cramps

Key benefits

• Improves blood circulation in limbs
• Reduces leg pain/cramps during walking (intermittent claudication)
• Improves walking distance
• Enhances microcirculation and tissue oxygenation

How Complamina Retard 500 mg Tablet works

Pentoxifylline is a hemorheologic agent that improves blood flow by increasing red blood cell flexibility and reducing blood viscosity. It also reduces platelet aggregation and improves microcirculation, helping oxygen delivery to tissues.

How to take Complamina Retard 500 mg Tablet

Tablet (extended-release): take exactly as prescribed, usually after meals to reduce stomach upset. Swallow whole with water; do not crush, chew, or split. Take at the same time each day.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can seriously disturb the heart's rhythm and blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Complamina Retard 500 mg Tablet

Most side effects of Complamina Retard are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• abdominal discomfort
• diarrhea
• dizziness
• headache
• flushing
• palpitations

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Complamina Retard 500 mg Tablet

Warnings and precautions

Use with caution in patients with bleeding disorders, recent cerebral/retinal hemorrhage, peptic ulcer disease, severe coronary artery disease, or hypotension. May increase bleeding risk especially with anticoagulants/antiplatelets; monitor for unusual bleeding/bruising. Caution in renal or hepatic impairment; dose adjustment/monitoring may be needed. Stop and seek care if severe chest pain, fainting, allergic reaction, or bleeding occurs.

Do not take Complamina Retard if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will check that this is suitable for your particular heart condition.

Interactions with other medicines

Anticoagulants (warfarin), antiplatelets (aspirin, clopidogrel), NSAIDs (ibuprofen, diclofenac), antihypertensives (may increase hypotension), theophylline (increased theophylline levels), ciprofloxacin/cimetidine (may increase pentoxifylline levels)

How to store Complamina Retard 500 mg Tablet

Store at room temperature (below 25°C), protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Complamina Retard 500 mg Tablet

Take it at the same time each day and do not miss doses. Keep an up-to-date list of your medicines with you.

Manufacturer and class

Manufacturer:

GERMAN REMEDIES

Therapeutic class:

Peripheral vasodilator / Hemorheologic agent

Drug class:

Methylxanthine derivative (hemorheologic agent; non-selective phosphodiesterase inhibitor)