Crestor 40 Tablet

Composition of Crestor 40 Tablet

Crestor 40 Tablet contains Rosuvastatin 40 mg. It belongs to the Statin (HMG‑CoA reductase inhibitor) class of medicines.

Uses of Crestor 40 Tablet

• Treatment of high cholesterol (hypercholesterolaemia) and mixed dyslipidaemia; lowering LDL-C and triglycerides and increasing HDL-C; prevention of cardiovascular events (heart attack
• stroke) in high-risk patients along with diet and lifestyle changes.

Key benefits

• Lowers LDL (bad cholesterol)
• Reduces triglycerides
• Raises HDL (good cholesterol)
• Helps prevent heart attack and stroke in high-risk patients

How Crestor 40 Tablet works

Rosuvastatin is a statin that inhibits HMG‑CoA reductase, the key enzyme for cholesterol synthesis in the liver. This increases hepatic LDL-receptor activity, leading to greater removal of LDL cholesterol from the blood and reduced triglycerides.

How to take Crestor 40 Tablet

Tablet for oral use. Take once daily at the same time each day, with or without food, as prescribed. Swallow whole with water; continue cholesterol-lowering diet and exercise. Do not stop without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely to cause immediate harm but may increase the risk of muscle and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Crestor 40 Tablet

Most side effects of Crestor are mild and settle as the body adjusts. Reported side effects include:

• Headache
• muscle pain (myalgia)
• abdominal pain
• nausea
• constipation
• weakness
• dizziness
• increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Crestor 40 Tablet

Warnings and precautions

High dose (40 mg) has higher risk of muscle injury (myopathy/rhabdomyolysis); seek care for unexplained muscle pain/weakness, fever or dark urine. Use with caution in liver disease, heavy alcohol use, hypothyroidism, kidney impairment, elderly, or history of statin-related muscle problems. Monitor liver enzymes and lipid profile as advised. Contraindicated in active liver disease; generally avoid in severe renal impairment unless specialist advises. Stop and consult doctor if pregnancy occurs.

Do not take Crestor if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy or while breastfeeding. Not for people with active liver disease.

Interactions with other medicines

Cyclosporine (contraindicated/avoid), gemfibrozil and other fibrates (↑ myopathy risk), niacin (↑ myopathy risk), protease inhibitors (e.g., lopinavir/ritonavir, atazanavir/ritonavir) (↑ rosuvastatin levels), warfarin (may ↑ INR—monitor), ezetimibe (↑ muscle risk), antacids containing aluminium/magnesium (reduce absorption—separate by ~2 hours)

How to store Crestor 40 Tablet

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Expert advice for Crestor 40 Tablet

Continue your diet, exercise and, above all, stopping smoking — the medicine adds to these, not replaces them. Get your lipid profile repeated as your doctor advises.

Manufacturer and class

Manufacturer:

ASTRAZENECAPHARMA INDIA LTD

Therapeutic class:

Antihyperlipidaemic

Drug class:

Statin (HMG‑CoA reductase inhibitor)